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WorksheetsMedicinal Chemistry-III
Total questions: 10
Worksheet time: 10mins
Which of the following is the general mechanism of action for erythromycin?
Inhibition of a metabolic enzyme
Inhibition of cell wall synthesis
Disruption of protein synthesis
Inhibition of nucleic acid transcription and replication enzyme
Which of the following antibiotics is a macrolide?
Chloramphenicol
Doxycycline
Erythromycin
Streptomycin
The antibiotic with an imine functionality is
Amphicillin
Roxithromycin
Doxycycline
Chloramphenicol
Macrolide antibiotics do not have
a large lactone ring
glycosidically linked amino sugar
a spiroketal group
a ketone group
Cycloguanil pamoate belongs to the class of
Antimalarials
Antihistaminics
Anidiabetics
Antiarrythymics
Removal of para nitro group of chloramphenicol
Decreases the toxicity
Increases the toxicity
Renders the compound water soluble
Decreases the potency
What is a prodrug ?
Pyrimethamine is a derivative of
Acridines
Biguanides
Pyrimidines
Quinolines
Which one of the following is acid labile
Erythromycin
Roxithromycin
Clarithromycin
Azithromycin
Chloramphenicol is assayed by
Acidimetry-alkalimetry
Colorimetric estimation of the diazotized compound
Non aqueous titration
Gravimetry
