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BIO615 quiz 3

Total questions: 20

Worksheet time: 12mins

Name
Class
Date
1.
What is the purpose of PCR?
a)
To produce millions of copies of DNA.
b)
To produce millions of copies of a specific region of DNA
c)
To add nucleotides to a DNA sequence
d)
To watch polymerase work.
2.
From where does Taq polymerase come?
a)
Bacteria that live in hydrothermal vents/hot springs.
b)
Cambodia
c)
The rain forest
d)
The CDC
3.
At what temperature does the Denature step of PCR occur?
a)
94-96° C
b)
50-65° C
c)
72° C
d)
Any temperature
4.
What is the function of a primer?
a)
To identify the particular region of DNA to be copied by PCR.
b)
To copy DNA.
c)
To create DNA nucleotides.
d)
To maintain the temperature of the PCR reaction.
5.
Why does PCR require a specific type of polymerase?
a)
Taq polymerase can withstand the range of temperatures in PCR without denaturing.
b)
Taq polymerase is the most inexpensive type of polymerase.
c)
Taq polymerase is the most common type of polymerase.
d)
A specific type of polymerase is unnecessary.
6.

A student performed a gel electrophoresis experiment. The results are represented in the diagram

below. Compared to the fragments at the top of the gel, the fragments at the lower end are

a)

larger, and move slower

b)

larger, and move faster

c)

smaller, and move faster

d)

smaller, and move slower

7.
Why do the fragments of DNA in gel electrophoresis travel away from the negative electrode?
a)
DNA is negatively charged so attracted to the positive end of the unit
b)
DNA is positively charged to attracted to the negative end of the unit
c)
the agarose gel in negatively charged
d)
the agarose gel is positively charged
8.
What is the purpose of gel electrophoresis?
a)
helps cut DNA
b)
count the genes in DNA
c)
separates DNA based on size
d)
allows for an exact replicated organism
9.
What applications can gel electrophoresis be used for?
a)
Parental Testing
b)
Criminal Investigations
c)
Sequence Endangered Species DNA
d)
All of the above
10.

How are buffers used in Electrophoresis?

a)

Conduct electricity

b)

Remove salts

c)

Add extension energy

d)

Dissolve excess DNA

11.

Southern blot is the technique for _____________ blot

a)

RNA

b)

Lipid

c)

DNA

d)

Protein

12.

In Southern blotting, ___________ type paper is used for blot transfer

a)

Nitrocellulose membrane or Nylon membrane filter

b)

Whatman filter paper

c)

Paper towel filter paper

d)

None

13.

Which technique is used for visualising the hybridised DNA fragments?

a)

Chromatography

b)

Autoradiography

c)

Crystallography

d)

Centrifugation

14.

A student researcher overexpresses an exogenous protein in cell culture and wants to determine if that protein, is in fact, overexpressed. What technique would best demonstrate that this protein is expressed in these cells?

a)

Northern blot

b)

Southern blot

c)

Western blot

d)

Eastern blot

15.

Which of the following techniques would be most useful to study gene expression?

a)

Northern blot

b)

Western blot

c)

Southern blot

d)

Eastern blot

16.
Based on these results whose blood was found in the blood stain at the crime scene?
a)
Bob
b)
Sue
c)
John
d)
Lisa
17.

Which two bear species are most closely related?

a)

Bear 1 and Bear 2

b)

Bear 1 and Bear 3

c)

Bear 2 and Bear 3

d)

There’s no way to tell

18.
Which suspect is likely guilty?
a)
Suspect #1
b)
Suspect #2
c)
Suspect #3
19.

A newly discovered RNA virus has been causing a pandemic. You are required to detect the virus from nasal swab. Identify the method that you have to use.

a)

rt-PCR

b)

PCR

c)

qPCR

d)

Southern Blotting

20.

Dideoxynucleoside triphosphates (ddNTPs) are used in Sanger sequencing because

a)

ddNTPs are fluorescent

b)

ddNTPs are incorporated very efficiently into DNA by DNA polymerase

c)

ddNTPs cannot be incorporated into DNA by DNA polymerase

d)

ddNTPs prevent further DNA synthesis once they are incorporated into the sequence