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Chromosome organization and molecular structure

Total questions: 16

Worksheet time: 8mins

Name
Class
Date
1.

Which of the following supports the argument that viruses are nonliving?

a)

Their DNA does not encode proteins

b)

They have RNA rather than DNA

c)

They are not cellular

d)

They do not evolve

2.

What kind of genetic material can be found in viruses?

a)

dsDNA

b)

RNA

c)

ssDNA

d)

All of the above

3.

Viruses _____.

a)

use the host cell to copy themselves and then viruses to synthesize their own proteins

b)

metabolize food to produce their own ATP

c)

use the host cell to copy themselves and make viral proteins

d)

manufacture their own ATP, proteins, and nucleic acids

4.

Which of the following features would characterize a lytic cycle of viral infection?

a)

it endows the host bacterium with the ability to cause disease

b)

it always leads to lyses of the host cell

c)

it is seen only with viruses that infect bacteria

d)

it is seen only with viruses that infect plants

5.

Which statement is incorrect about bacterial chromosomes

a)

Are circular in shape

b)

There can be multiple copies of chromosomes in a bacterial cell

c)

Consist of only structural genes

d)

There is a single origin of replication

6.

How are circular bacterial chromosomes compacted to fit a bacteria cell?

a)

First the circular chromosome get folded into loop domains then further supercoiled

b)

First the circular chromosome get supercoiled then further folded into loop domains

c)

First the circular chromosome enters the cell and produces copies of itself with the host material

d)

First the circular chromosome become uncoiled then cut using enzymes

7.

Negative supercoiling is mediated by DNA Gyrase to introduce twists in the circular chromosome

a)

True

b)

False

8.

Positive supercoiling relaxes the twisting of the chromosome back into circular shape and is mediated by Topoisomerase I

a)

True

b)

False

9.

Why is the genome size not an indicator of the number of genes

a)

The big size can be due to multiple genes that encode proteins

b)

The big size can be due to accumulation of repetitive sequences

c)

The big size can be due to the size of the organism itself is big

d)

The big size can be due to genotypic variation and environment

10.

In eukaryotic chromosomes, what are required for chromosomal replication and segregation.

a)

Origins of replication

b)

Centromeres

c)

Telomeres

d)

All of the above

11.

What is sequence complexity?

a)

the amount of structural genes found throughout the genome

b)

the number of nonrepetitive sequences throughout the genome

c)

the number of times a particular base sequence appears throughout the genome

d)

the amount of moderately repetitive and highly repetitive sequences that appears throughout the genome

12.

What is the repeating structure unit in a eukaryotic chromosome?

a)

histone

b)

nucleosome

c)

nucleotide

d)

protein

13.

A nucleosome is best described as

a)

nucleosomes coiled around each other

b)

a DNA strand wrapped around histone proteins

c)

one fully-packaged DNA molecule

d)

one strand of DNA double-helix

14.

Which is TRUE concerning the 30nm fiber

a)

is though to be in a solenoid formation

b)

The histone H1 linker is involved in the formation

c)

involves the folding of strands into radial loop domains

d)

connected to a protein scaffold

15.

.... is the fourth level of chromosomal compaction before further compaction into a ....

a)

nucleosome, 30nm fiber

b)

30nm fiber, radial loop domain

c)

radial loop domain, chromatin

d)

chromatin, chromosome

16.

Which of the following is NOT a benefit of DNA packaging?

a)

all of a cell's DNA can fit into the nucleus

b)

DNA is protected from damage

c)

genes can be accessed as-needed

d)

chromosomes can be reshuffled frequently