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chapter 14 chromosomes and human inheritance

Total questions: 50

Worksheet time: 54mins

Name
Class
Date
1.

In a pedigree, such as the one in Figure 14–4, a circle represents a(an)

a)

male.

b)

female.

c)

child.

d)

adult.

2.
Human males have
a)
one X chromosome only.
b)
two X chromosomes.
c)
one X and one Y chromosome.
d)
two Y chromosomes.
3.
How many chromosomes are shown in a normal human karyotype?
a)
2
b)
23
c)
44
d)
46
4.
Which of the following combinations of sex chromosomes represents a female?
a)
XY
b)
XXY
c)
XXXY
d)
XX
5.

How many generations are shown in the pedigree in Figure 14–5?

a)

2

b)

4

c)

6

d)

8

6.
_______________ is a sex linked hereditary disease in which clotting factors are missing from the blood. 
a)
PKU
b)
Sickle Cell Anemia
c)
Cystic Fibrosis
d)
hemophillia
7.
What genetic disorder causes the body to produce unusually thick mucus in the lungs and intestines? 
a)
Cystic Fibrosis
b)
Sickle Cell
c)
Down Syndrome
d)
Hemophilia
8.
Karyotypes are useful for detecting _______.
a)
Missing or extra chromosomes
b)
All genetic disorders
c)
Cystic Fibrosis
d)
Huntington's Disease
9.
A person with Down syndrome has ______ copies of chromosome 21.
a)
1
b)
2
c)
3
d)
4
10.
In a pedigree the circle represents a 
a)
male
b)
female
c)
child
d)
adult
11.
Gene located on the X or Y chromosome
a)
Homozygous dominant
b)
nondisjunction
c)
Sex-linked gene
d)
Autosomal Disorder
12.
What is the name of the protein that is not normal in people with sickle-cell disease?
a)
mucus
b)
clotting protein
c)
karyotype
d)
hemoglobin
13.

On a pedigree chart fully shaded squares are___

a)

male affected

b)

female affected

c)

male not affected

d)

female not affected

14.

A half shaded square tells us that the individual is

a)

male affected

b)

female affected

c)

male carrier

d)

female carrier

15.

Diagrammed family history that is used to study inheritance patterns of a trait through several generations and that can be used to predict disorders in future offspring.

a)

Pedigree

b)

Carrier

c)

Autosome

d)

Karyotype

16.

What is the genotype of I-1?

a)

XhY

b)

XhXh

c)

Hh

d)

hh

17.

What is the mode of inheritance?

a)

Sex linked recessive

b)

Autosomal recessive

c)

Autosomal dominant

18.

What is the mode of inheritance?

a)

Sex linked recessive

b)

Autosomal recessive

c)

Autosomal dominant

19.

What is the genotype of I-1?

a)

AA

b)

A-

c)

Aa

d)

XAXa

20.

What is the mode of inheritance?

a)

Sex linked recessive

b)

Autosomal recessive

c)

Autosomal dominant

21.

What is the genotype of III-11?

a)

XAXa

b)

Aa

c)

aa

d)

XAX-

22.

What is the genotype of II-2?

a)

XHXh

b)

Hh

c)

hh

d)

XHX-

23.

What is the mode of inheritance?

a)

Sex linked recessive

b)

Autosomal recessive

c)

Autosomal dominant

24.

What is the genotype of II-3?

a)

XAXa

b)

aa

c)

Aa

d)

A-

25.

What is the mode of inheritance?

a)

Sex linked recessive

b)

Autosomal recessive

c)

Autosomal dominant

26.

What is the mode of inheritance?

a)

Sex linked recessive

b)

Autosomal recessive

c)

Autosomal dominant

27.

What is the genotype of II-7?

a)

aa

b)

XaY

c)

A-

d)

XAY

28.

A picture of all the chromosomes in a cell arranged in pairs

a)

genetic disorder

b)

Punnett Square

c)

Pedigree

d)

karyotype

29.

Chromosomes that determine the sex of an individual

a)

sex-linked trait

b)

Punnett Square

c)

sex chromosomes

d)

karyotype

30.

What is this a picture of?

a)

pedigree

b)

karyotype

c)

genome

d)

chromosome

31.
Besides genetics, what can alter or change a gene? (HINT: Height is an example.)
a)
cancer
b)
environment
c)
doctors
d)
television
32.
What can affect a person's height? 
a)
Genetics 
b)
Environmental factors 
c)
Parents
d)
Genetics and environmental factors
33.
A person that has hemophilia
a)
will die
b)
bleeds easily
c)
has too much mucus built up in their bodies
d)
is colorblind
34.

An example of a sex-linked trait is

a)

widow's peak

b)

hitchhiker's thumb

c)

red-green color blindness

d)

earlobe attachment

35.

The failure of replicated chromosomes to separate during meiosis is called

a)

nondisjunction

b)

gene cloning

c)

genetic engineering

36.
How are individuals III-2 and II-4 related?
a)
Cousins
b)
Dad and Daughter
c)
Uncle and Niece
d)
Grandpa and Granddaughter
37.
How many girls in this family express this recessive disorder?
a)
4
b)
5
c)
6
d)
7
38.

___________ is a type of medical test that looks for changes in chromosomes, genes, and proteins.

a)

Stem cell

b)

Cloning

c)

Genetic screening

39.

Genetic screening can be used to determine _______________

a)

•if a person has a specific genetic condition

b)

•if a person has a chance to pass on specific genetic conditions to offspring

c)

•if a person is particularly vulnerable or resistant to certain viruses or bacteria

d)

•if a person is likely to develop a genetic disorder later in life

e)

All of the above

40.

In the US, all newborn babies must undergo genetic screening for certain conditions. An example is a _________ test.

a)

MLB

b)

NFL

c)

PKU

d)

DMV

41.

In this human chromosomal variation which affects the 21st chromosome, an extra copy of the 21st chromosome adheres to another chromosome. It is the rarest form of trisomies and the only inherited type.

a)

Mosaic Down's syndrome

b)

Trisomy 21

c)

Translocation

d)

Deletion

42.

This invasive procedure requires the extraction of fluid from the amniotic sac of the mother.

a)

Chorionic Villus Sampling

b)

Amniocentesis

43.

PKU is when the body...

a)

cannot process high protein foods

b)

only makes proteins

c)

cannot digest lipids

d)

cannot digest carbohydrates

44.
What is an ultrasound
a)
An invasive test
b)
A non invasive test
45.
What is an amniocentesis? 
a)
An invasive test
b)
A non invasive test
46.

Aneuploids

a)

Always have too many chromosomes

b)

Are organisms with the typical number of chromosomes

c)

Are organisms that do not live long

d)

Have numbers of chromosomes that are different from the expected diploid number

47.

The karyotype shown in the image is of an individual who has aneuploidy due to

a)

Too many copies of chromosome 21

b)

Too many copies of chromosome 22

c)

Too many copies of chromosome 1

d)

Too many copies of the X chromosome

48.

Polyploidy is when

a)

A chromosome is present in more than the typical diploid number

b)

When there are too many multiples of ALL the chromosomes

c)

There are many cells

d)

There are many chromosomes

49.
Nondisjunction can result in 
a)
trisomy conditions
b)
monosomy conditions
c)
additional sex chromosomes
d)
all of these
50.
Down's syndrome occurs because of a(n)
a)
missing sex chromosome
b)
extra sex chromosome
c)
additional 21st chromosome
d)
additional 18th chromosome

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