Font size
WorksheetsChemotherapy of reproductive system cancers
Total questions: 7
Worksheet time: 11mins
A 55-year-old woman is taking tamoxifen for breast cancer. She complains of vaginal bleeding. She enquires with the Oncologist the reason for her having vaginal bleeding.
Which of the following is the best explanation?
It has estrogen agonist effect of both the breast and uterus
causing endometrial hyperplasia on the uterus.
It is an estrogen antagonist in the breast and uterus, leading to loss of endometrial cells.
It has no effect on uterus, the bleeding is due to antiplatelet effect.
It has an antagonist effect on the breast but an agonist effect on the uterus.
A 48-year-old woman presented with a 3-cm nodule in the left breast and a dull hip pain for more than six months. Workup revealed bone metastases including the pelvis and low-volume malignant pleural effusion in the right lung. Biopsy and subsequent pathology findings revealed HER2+ breast cancer. She is given a standard chemotherapy regimen including cisplatin together with one of the drugs from the options below?
Which is the most appropriate drug to be added to the chemotherapy regimen in this case?
Tamoxifen
Trastuzumab
Fulvestrant
Exemestane
A 70-year-old man has severe urinary hesitancy associated with benign prostatic hyperplasia. His physician prescribes a drug that acts on the prostate to reduce the size.
Which of the following drugs did the physician most likely prescribe?
Leuprolide
Prazosin
Finasteride
Bicalutamide
A 67-year-old man with metastatic prostate cancer is administered weekly im depot leuprolide acetate.
Which is the best explanation for the mechanism of action of leuprolide?
It increases in LH, FSH and acts as GnRH agonist
Downregulation of GnRH receptors in pituitary.
Inhibits 5 alpha reductase
Blocks the effect of androgen on androgen receptors in pituitary.
Cisplatin is a/an
alkylating agent
anthracycline
taxane
vinca alkaloid
A 71-year-old woman is diagnosed with hormonally-dependent breast cancer. Her Oncologist wants to prescribe an anticancer drug.
Which of the following is the most likely drug to be prescribed?
Tamoxifen
Bicalutamide
Exemestane
Trastuzumab
Targeted drugs are
A. anticancer drugs that kill all cells.
anticancer drugs that inhibit cancer cell proliferation
anticancer drugs that prevent growth and proliferation of cancer cells.
anticancer drugs that only inhibits DNA synthesis.
