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Total questions: 10

Worksheet time: 20mins

Name
Class
Date
1.

In a clinical dose range, renal failure will significantly alter the termination of action of which drug?

a)

Vecuronium

b)

Succinylcholine

c)

Sevoflurane

d)

Fentanyl

e)

Propofol

2.

Which class of medications is the most common cause of anesthetic drug induced anaphylaxis?

a)

muscle relaxants

b)

propofol

c)

opioids

d)

ester local anesthetics

e)

antibiotics

3.

Which of the following correctly identifies the number of subunits in a nicotinic acetylcholine-gated ion channel?

a)

2

b)

3

c)

4

d)

5

e)

7

4.

A nondepolarizing muscle relaxant (NMDR) binds to which subunit of the nicotinic acetylcholine receptor (nAChR)?

a)

alpha

b)

beta

c)

delta

d)

epsilon

e)

gamma

5.

Liver failure will have the most significant effect on the duration of action of which nondepolarizing muscle relaxant (NMDR)?

a)

vecuronium

b)

cisatracurium

c)

rocuromium

d)

atracurium

e)

succinylcholine

6.

a patient has received a nondepolarizing muscle relaxant (NMDR) for many hours in the ICU and becomes hypotensive. The hypotension is thought to be due to elevated levels of laudanosine. Which NMDR did the patient receive?

a)

vecuronium

b)

rocuronium

c)

atracurium

d)

cis-atracurium

e)

pacuronium

7.

During surgery an adult patient is given a second dose of succinylcholine approximately 5 minutes after the first dose. This scenario increases the risk of which of the following side effects of succinylcholine?

a)

malignant hyperthermia

b)

prolonged paralysis

c)

postoperative myalgias

d)

bradycardia

e)

histamine release

8.

Administration of succinylcholine can increase potassium levels, and in susceptible patients this can lead to significant hyperkalemia. In which of the following conditions is succinylcholine safe to use?

a)

burn injury

b)

Guillain-Barre' syndrome

c)

massive trauma

d)

chronic renal failure

e)

closed head injury

9.

Inhaled anesthetics and TIVA can potentiate the effects of nondepolarizing muscle relaxants (NMDRs). Which of the following is the most potent?

a)

desflurane

b)

sevoflurane

c)

isoflurane

d)

nitrous oxide

e)

propofol

10.

Many antibiotics can potentiate the effects of nondepolarizing muscle relaxants (NMDRs). Which antibiotic has NO effect on neuromuscular blockade?

a)

gentamicin

b)

lincomycin

c)

clindamycin

d)

cefazolin

e)

tetracycline