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WorksheetsAntihistamines
Total questions: 13
Worksheet time: 8mins
A 43-year-old heavy machine operator complains of seasonal allergies. Which one of the following medications would be most appropriate for management of his allergy symptoms?
Cyclizine
Doxylamine
Hydroxyzine
Fexofenadine
Which one of the following statements concerning
H1 antihistamines is correct?
Second-generation H1 antihistamines are relatively free of adverse effects.
Because of the established long-term safety of first-generation H1 antihistamines, they are the first choice for allergic rhinitis.
The motor coordination involved in driving an automobile is not affected by the use of first-generation H1 antihistamines.
H1 antihistamines can be used in the treatment of acute anaphylaxis.
Both first- and second-generation H1 antihistamines readily penetrate the blood–brain barrier.
Which of the following medications has the most potential to significantly impair the ability to drive an automobile?
Diphenhydramine
Levocetirizine
Fexofenadine
Ranitidine
Which of the following histamine receptor antagonists is known to enter the central nervous system readily and is known to be sedative?
Hydroxyzine
Cetirizine
Desloratadine
Loratadine
Fexofenadine
Which of the following statements about histamine receptor antagonists is MOST ACCURATE?
Most antihistamines have no antimuscarinic effects.
α-Adrenergic effects of antihistamines may cause hypertension.
First-generation antihistamines have no sedative side effects.
Because of their cholinergic properties, antihistamines may not be effective in the relief of vertigo associated with motion sickness.
Headache may be associated with some second-generation antihistamines
A passenger sitting next to you in a plane boasts that he was a famous biochemist. He said he carboxylated a sedating antihistamine, and it is now only partially sedating and is a very well-known drug in the market. Which drug is he talking about?
Hydroxyzine
Cetirizine
Diphenhydramine
Doxylamine
Cyproheptadine
Which of the following is an H1-receptor antagonist that also has serotonin receptor antagonism on the appetite center with the ability to stimulate appetite?
Hydroxyzine
Loratadine
Diphenhydramine
Cetirizine
Cyproheptadine
Your neighbor said she used an H1 antihistamine that was available over-the-counter (OTC), and it caused her marked drowsiness and dry mouth and she slept quite longer than usual. Which is the most possible drug that she used?
Loratadine
Levocetirizine
Diphenhydramine
Fexofenadine
Desloratadine
A patient is going on a deep sea fishing trip and is worried about motion sickness. Which of the following would be the most appropriate?
Dimenhydrinate 1 hour prior to departure
Desloratadine 1 hour prior to departure
Doxylamine 1 hour prior to departure
Meclizine at onset of symptoms
A patient has a severe ear infection that is associated with significant vertigo. Which of the following might be helpful?
Azelastine
Brompheniramine
Meclizine
Olopatadine
A 23-year-old woman suffers from recurrent episodes of angioneurotic edema with release of histamine and other mediators. Which of the following drugs is the most effective physiologic antagonist of histamine in smooth muscle?
Cetirizine
Epinephrine
Granisetron
Ranitidine
Sumatriptan
A 20-year-old woman is taking diphenhydramine for severe hay fever. Which of the following adverse effects is she most likely to report?
Muscarinic increase in bladder tone
Nausea
Nervousness, anxiety
Sedation
Vertigo
The hospital Pharmacy Committee is preparing a formulary for staff use. Which of the following is a correct application of the drug mentioned?
Alosetron: for obstetric bleeding
Cetirizine: for hay fever
Ergonovine: for Alzheimer’s disease
Ondansetron: for acute migraine headache
Ranitidine: for Parkinson’s disease
