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WorksheetsMARCH 2020 Local Anesthesia : Dr Untalan
Total questions: 10
Worksheet time: 6mins
1. The primary mechanism of action of local anesthetics involves the blockade of which of the following ion channels?
Inactivated, voltage-gated, Na+ channels
Resting, voltage-gated ,K+ channels
Inactivated, ligand-gated, K+ channels
Resting, ligand-gated, Na+ channels
2. Which of the following nerve fibers are most sensitive to the action of local anesthetics?
Fiber of small diameter
Rapidly firing fibers
Unmyelinated fibers
Fiber of large diameter
3. When a local anesthetic is applied to a nerve fiber, which of the following nerve properties will most likely increase?
Rate of rise of the action potential
Amplitude of the action potential
Refractory period of the nerve
Conduction velocity of the nerve
4. The last to be blocked function after a local anesthetic is applied to a nerve?
Motor function
Pain sensation
Sympathetic function
Proprioception
5. The neutral form of local anesthetics is mainly responsible for which of the following properties of the drug?
Potency
Systemic toxicity
Facilitates entry of the drug
Half-life
6. The application of local anesthetic directly to an infected wound would result to a decrease in potency due to?
Highly vascularized
Poorly vascularized
High extracellular K+ concentration
Low extracelluar pH
7. Which of the following local anesthetics is mainly metabolized via hepatic carboxylesterase?
Bupivacaine
Cocaine
Tetracaine
Benzocaine
8. Which of the following local anesthetic agent is the most cardiotoxic?
Ropivacaine
Tetracaine
Lidocaine
Bupivacaine
9. Which of the following are the main purposes for adding a vasoconstrictor drug to a local anesthetics?
To speed up the onset of the anesthetic effect
To increase the duration of anesthetic effect
To decrease the risk of allergic reactions of the drug
To increase the affinity of the drug for the Na+ channels
10. A 20 y/o male patient was scheduled for elective varicocoelectomy under spinal anesthesia.
Upon detailed history taking, patient revealed an anaphylactic reaction 6 months ago apparently due to a para-aminobenzoic acid containing facial cream. Which of the following local anesthetic would be appropriate for this patient?
Tetracaine
Bupivcaine
Benzocaine
Cocaine
