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Revision: Chapters 7 and 8

Total questions: 21

Worksheet time: 14mins

Name
Class
Date
1.

Select the true statement

a)

all immunogens are antigens

b)

all antigens are immunogens

c)

antigens are produced by T lymphocytes to defend against non-self antigens

d)

antigens are produced by B lymphocytes to defend against immunogens

2.

Do all antigens elicit an immune response?

a)

Yes

b)

No

3.

Thick waxy cuticles are an example of

a)

Physical Barriers

b)

Chemical Barriers

c)

Microbiological Barriers

4.

Epithelial cells in animals would be an example of

a)

Physical barriers

b)

Chemical barriers

c)

Microbiological barriers

5.

Acidic vaginal secretions would be an example of

a)

Physical barrier

b)

Chemical barrier

c)

Microbiological barrier

6.

Innate immune responses include (select one or more)

a)

Occur within hours

b)

Typically take weeks

c)

Are fixed responses

d)

Lead to memory

e)

Don't lead to memory

7.

Select the different types of innate immune cells

a)

Basophil

b)

Macrophage

c)

Mast cell

d)

Chemokines

e)

Dendritic cell

8.

Complement proteins circulate in the lymph vessels and help kill foreign cells

a)

True

b)

False

9.

Interferons are non-specific and will act on any virus

a)

true

b)

false

10.

Select all the cells/molecules involved in inflammation

a)

Mast cells

b)

Neutrophils

c)

Basophils

d)

Cytokines

e)

Histamines

11.

A fever will decrease the replication of pathogens like viruses and bacteria by destroying the genetic material within the pathogens.

a)

True

b)

False

12.

Pus contains leukocytes

a)

Yes

b)

No

13.

immunity in an organism

a)

causes it develop a disease after exposure to a pathogen

b)

makes it unable to respond to an infective agent

c)

makes it able to resist infection

d)

is the absence of a vaccination

14.

During the great plague in the seventeenth century millions of people died. Others, many who often tended sick people, remained unaffected.


It is most likely that these unaffected people had:

a)

systems were unable to identify the plague-causing organism

b)

systems that were unable to produce T and B cells

c)

a natural immunity to the plague-causing organisms

d)

been vaccinated against the plague-causing organism

15.

Inflammation involves the

a)

decrease of blood flow to an area

b)

generation of heat in an area

c)

decrease of capillary permeability

d)

removal of white blood cells near the area

16.

An event that leads to the development of inflammation is

a)

taking oral medicine to treat an infection

b)

phagocytes engulfing bacteria

c)

an infective agent entering a cut in the skin

d)

applying ointment to a wound area

17.

Innate immune responses are critical to maintaining the health of an individual because:

a)

they are specific to the antigens on the pathogenic organisms

b)

the innate response produces antigens which bind antibodies to mast cells

c)

they provide immediate and continuous protection against foreign antibodies

d)

none of the above

18.

Natural active immunity is achieved as a result of:

a)

exposure to live attenuated vaccines

b)

infection by a particular bacteria or virus

c)

the administration of antibodies or antitoxin specific to a particular microorganism

d)

adequate breast-feeding in newborn infants

19.

Lupus is a condition that results in the increased secretion of antibodies that attach themselves to healthy cells in a patient’s body. The accumulation of these antibodies causes inflammation, joint pain, rash, fatigue and fever.


Lupus is an example of

a)

an allergic reaction.

b)

an autoimmune disease.

c)

an immune deficiency disease.

d)

a complement protein response.

20.

Antigen-presenting cells deliver antigens to lymphocytes found within lymphoid tissue. These lymphocytes recognise these antigens as being non-self, causing the lymphocytes to become activated and increase in number. Which of the following lymphocytes are activated by antigen-presenting cells?

a)

T helper cells

b)

dendritic cells

c)

plasma cells

d)

neutrophils

21.

mAb's that have been attached to a chemotherapy drug, toxin or radioactive particle are an example of:

a)

Bispecific mAb's

b)

Chimeric mAb's

c)

Humanised mAb's

d)

Conjugated mAb's