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ARTILECT PARACLINICAL PRELIMS

Total questions: 29

Worksheet time: 14mins

Name
Class
Date
1.

1. This is a biopsy finding of a person presenting with haematuria, proteinuria (>3gm/day), oliguria and red cell casts in the urine. What is the most probable diagnosis?

a)

Post Streptococcal Glomerulonephritis

b)

Minimal Change Disease

c)

IgA Nephropathy

d)

Rapidly Progressive Glomerulonephritis

2.

Which of the following about Monoclonal Antibodies is not true?

a)

“zu” in Certolizumab indicates it is humanized Monoclonal Antibody.

b)

“u” in Raxibacumab indicates it is 100% human Monoclonal Antibody.

c)

mu” in Adalimumab indicates it is 100% murine Monoclonal Antibody.

d)

“xi” in Abciximab indicates it is more murine and less human Monoclonal Antibody.

3.

Which of the following is not true about CD markers and the type of Acute Leukemia?

a)

Cells are CD34+, CD19+ -> B-lymphocyte ALL

b)

Cells are CD34+, CD19+, MPO+ -> Biphenotypic Acute Leukemia

c)

Cells are CD34+, CD19+, CD117+ -> Biphenotypic Acute Leukemia

d)

A) Some cells are CD34+, CD19+ and some cells are CD34+, MPO+ -> Mixed Phenotypic Acute Leukemia

4.

What is the drug used in the treatment of pneumonia caused by vancomycin-resistant Staph. Aureus (VRSA) according to the latest guidelines?

a)

Daptomycin

b)

5th generation Cephalosporins

c)

Linezolid

d)

Rifabutin

5.

Which of the following statements about the given image is false?

a)

It is used to detect toxin of C.diphtheriae.

b)

It is used to detect capsular antigen of Cryptococcus.

c)

This is a two-dimensional double immunodiffusion test.

d)

Antibody is placed in central well and the surrounding wells are filled with various antigens.

6.

A 17 year old female develops palpitations within half an hour after a gunshot wound to the abdomen.

O/E: Her HR= 112/min.;BP= 80/30mmHg.Her skin is cool& clammy to touch.Which of the following organ specific change is most likely to occur within 48 hours?

a)

Renal Passive Congestion

b)

Acute hepatic infarction

c)

Cerebral Basal Ganglia Haemorrhage

d)

Pulmonary Diffuse Alveolar Damage

7.

Which of the following stains is used for measuring the density of neurons

a)

Luxol-fast blue stain

b)

VGE

c)

Nissl stain

d)

Holzer stain

8.

A patient complains of developing erythema, tenderness, tingling, numbness, dry rash and desquamation over the palms and soles.


The patient was undergoing a treatment and the doctor diagnosed this as an adverse effect of a particular drug in the patient’s therapeutic regimen.

Which of the following drugs is associated with this condition?

a)

Vancomycin

b)

Amiodarone

c)

Capecitabine

d)

Theophylline

9.

Which of the following microbes is most commonly associated with the neoplastic condition shown in the histopathological slide given above?

a)

Human T-lymphotropic virus-1

b)

Human herpes virus -8

c)

Hepatitis C virus

d)

Epstein-Barr virus

10.

A 55yr old man presented with fatigue,weight loss,night sweats and splenomegaly.Peripheral blood smear examination revealed basophilia and FISH study revealed the shown image.


What is the drug of choice for this condition?

a)

Rituximab

b)

Imatinib

c)

Bevacizumab

d)

Bortezomib

11.

The IHC study of breast biopsy of a woman revealed the shown combination of images.


What is the molecular classification of the breast carcinoma?

a)

Luminal A

b)

Basal

c)

Claudin low

d)

Her 2 neu enriched

12.

(Continuation Q)

The IHC study of breast biopsy of a woman revealed the given combination of images.


Can hormonal therapy be added in her treatment- the answer goes YES!


If yes then what will be drug used if the women is of 50yrs age?

a)

Letrozole

b)

Tamoxifen

c)

Trastuzumab

d)

Fulvestrant

13.

Identify the disease

a)

Melanoma

b)

actinic keratosis

c)

basal cell CA

d)

squamous cell CA

14.

A 65 yr old female suffering from severe psoriasis is taking methotrexate 5mg once a week for 3 months ,suddenly she developed bleeding from gums what should she be prescribed to stop the bleeding immediately before doing the complete blood count and taking further steps?

a)

aspirin

b)

oral vit K agonists

c)

Tranexamic acid

d)

alteplase

15.

A 19 yr old girl admitted to emergency after an intentional acetaminophen overdose.You have been asked to review some blood test reports. Which of the following metabolic abnormality most strongly suggest severe poisoning by the drug?

a)

Hyperkalemia

b)

hypoglycemia

c)

hypokalemia

d)

hyponatremia

16.

Which of the following is not true about the given conditions

a)

A is toxaemia not a bacteremia

b)

B is non toxin mediated

c)

In B bacteria is non invasive, present only at the pharynx

d)

there is increasing trend of B nowadays especially in vaccinated children

17.

The organism shown in the following electron micrographic image belongs to the which of the following class?

a)

Cestoda

b)

Nematoda

c)

Virus

d)

Spirochaete (bacteria)

18.

The given serology report of a Hepatitis B patient Is most likely in which stage?

a)

Chronic HBV infection

b)

Acute HBV infection with recovery

c)

Window period

d)

Carrier state

19.

Which of the following organism other than the commonly known one causes similar lesions as shown in image?

a)

Molluscum contagiosum

b)

Sporothrix schenkii

c)

Penicillium marneffei

d)

Borrelia burgdorferi

20.

c-kit point mutations are associated with all of the following tumors except

a)

Seminoma

b)

Mastocytosis

c)

GIST

d)

Colorectal cancer

21.

The figure below shows DNA electrophoresis in a patient. Choose the false statement about the type of cell death depicted by pattern A ?

a)

Plasma membrane is intact.

b)

The major mechanism in mammalian cells is the death-receptor initiated pathway.

c)

Adjacent inflammation is absent

d)

Can be seen even in physiological conditions

22.

According to Vaughan William classification of anti-arrhythmic drugs, all of the following can cause QT-Prolongation except

a)

Class 3

b)

Class 1a

c)

Class 1b

d)

Class 1c

23.

All of these organisms are associated with cat bite or scratch except

a)

Rabies

b)

Pasturella multocida

c)

Toxoplasma gondii

d)

Bartonella henselae

24.

All the following are associated with chicken-wire like findings on histopathology except

a)

Oligodendroglioma

b)

Chondroblastoma

c)

Pemphigus vulgaris

d)

Alcoholic cirrhosis

25.

You have injected a patient with intra arterial thiopentone during the start of an elective and non emergency surgical procedure. After realizing the mistake what would you do.

a)

Keep on injecting more thiopentone through the cannula as IA dose is higher. Give systemic arterial dilators. Continue the surgery

b)

Immediately remove he cannula. Give IV thiopentone continue the surgery.

c)

Keep the cannula in place, dilute with saline and give Intra arterial Local anesthetic +- vasodilator.

d)

Continue with the anesthetic procedure. No modification in course of treatment is required

26.

A patient of DM type1 taking insulin if takes any Beta blocker along with it ,all the warning symptoms in hypogylcemia will be lost except

a)

tachycardia

b)

palpitation

c)

tremors

d)

sweating

27.

In senile dementia (Alzheimers disease) drugs like donepezil,rivastigmine are used as the etiology of such dementia is

a)

degeneration of peripheral nerve

b)

demyelination of nerves

c)

degeneration of cholinergic neurons in the basal nucleus of Meyernet

d)

loss of nerve cells in substantia nigra

28.

Your name, COLLEGE, YEAR


(MUST MATCH WITH REGISTRATION, OTHERWISE DISQUALIFIED)

4 lines
29.

score our performance on following parameters


(Quality, thoughtfulness, Team effort, TEAM SPIRIT)

a)

5 (Awesome)

b)

4

c)

3

d)

2

e)

1 (Pathetic)