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Paper 1 Biology

Total questions: 40

Worksheet time: 41mins

Name
Class
Date
1.

Which is correct about the organelles listed in the table?

a)

1 and 3

b)

1 and 4

c)

2 and 3

d)

2 and 4

2.
The graticule and stage micrometer are used to measure cells. Which is the correct reason why the graticule is calibrated?
a)
The graticule can be used to make measurements
b)
The graticule is magnified by the objective lens
c)
The graticule magnifies the specimen
d)
The graticule makes comparison
3.

The following are all features of eukaryotic cells (1) chloroplast (2) Golgi apparatus (3) lysosome (4) mitochondrion (5) nucleus. Which of these has a single membrane?

a)

1 and 2

b)

2 and 3

c)

3 and 4

d)

4 and 5

4.

A piece of mammalian tissue was homogenised and centrifuged. The biochemical activity of four subcellular fractions was investigated. Which diagram indicates the fraction with maximum synthesis of messenger RNA?

a)

A

b)

B

c)

C

d)

D

5.

A piece of mammalian tissue was homogenised and centrifuged. The biochemical activity of four subcellular fractions was investigated. Which diagram indicates the fraction with maximum synthesis of ATP?

a)

A

b)

B

c)

C

d)

D

6.

From the table, which rows show the chemical groups present in the biological molecules listed?

a)

1, 2 and 3

b)

1, 2 and 4

c)

1, 3 and 4

d)

2, 3 and 4

7.

Which molecular bonds will be broken by hydrolysis when a molecule of glycogen is converted to glucose

a)

A

b)

B

c)

C

d)

D

8.

The formation of glycosidic and peptide bonds is responsible for polymerisation in some biological molecules. With reference to the table, which bonds are found in which molecules?

a)

A

b)

B

c)

C

d)

D

9.
Which is correct for a non-competitive inhibitor of enzyme action? (1) increasing the concentration of the enzyme's substrate will reduce its effect (2) it reduces the activation energy requried for a reaction to take place (3) it reduces the maximum rate of reaction
a)
1 only
b)
3 only
c)
1 and 3 only
d)
2 and 3 only
10.
The rate of enzyme-catalysed reactions in human cells is regulated. Which may be involved in such regulation? (1) a change in enzyme concentration (2) a change in substrate concentration (3) inhibition by the final product of the reaction
a)
1 and 2 only
b)
1 and 3 only
c)
2 and 3 only
d)
1, 2 and 3
11.

The effect of substrate concentration on an enzyme-catalysed reaction was measured in three different conditions: with no inhibitor, with a competitive inhibitor, with a non-competitive inhibitor. The graph shows the results. Which statement is correct?

a)

X is a competitive inhibitor which binds to a site other than the active site of the enzyme

b)

X is a non-competitive inhibitor which has as similar shape to the active site of the enzyme

c)

Y is a competitive inhibitor which has a similar shape to the active site of the enzyme

d)

Y is a non-competitive inhibitor which binds to a site other than the active site of the enzyme

12.

Which words from the table correctly complete the paragraph about enzymes? When the pH of an environment is decreased below the optimum pH of an enzyme, ……….(1)......... bonds between adjacent ……….(2)........ groups, holding the ……….(3)......... structure, are disrupted.

a)

A

b)

B

c)

C

d)

D

13.
Which of these features increases the efficiency of ion uptake by a root hair cell? (1) many mitochondria in the cell (2) high concentration of ions in the vacuole (3) proteins carriers in the cell surface membrane
a)
1, 2 and 3
b)
1 and 3 only
c)
1 only
d)
2 and 3 only
14.
What can increase the fluidity of the cell surface membrane at low temperature? (1) double bonds between carbon atoms in the fatty acid chains (2) cholesterol (3) fatty acids having shorter chains
a)
1, 2 and 3
b)
1 and 3 only
c)
1 only
d)
2 and 3 only
15.

A student observed the cells in the growing region (meristem) of an onion and obtained the data shown in the table. Which percentage of cells contains chromosomes that appear as two chromatids?

a)

7.3

b)

8.9

c)

95.9

d)

97.5

16.
During which phase of the cell cycle does DNA replication take place?
a)
G1
b)
G2
c)
M
d)
S
17.

Strips of potato tuber tissue were immersed in distilled water or in sucrose solution of different concentrations. The graph shows the percentage change in length of the strips. Which statement explains the change that occurred in the potato strips immersed in 0.1 mol/dm3 sucrose solution?

a)

Sucrose molecules diffused into the potato cells

b)

Sucrose molecules were actively transported into the potato cells

c)

The water potential of the sucrose solution was less negative than the water potential inside the cells

d)

The water potential of the sucrose solution was more negative than the water potential inside the cells

18.

To which of the processes shown does mitosis make a contribution?

a)

A

b)

B

c)

C

d)

D

19.
Which process would allow the movement of large protein molecules OUT of the cell?
a)
Active transport
b)
Exocytosis
c)
Facilitated Diffusion
d)
Phagocytosis
20.
How does increasing substate concentration affect the rate of an enzyme-catalysed reaction in the presence of a competitive inhibitor?
a)
The rate of the reaction decreases
b)
The rate of the reaction decrease initially and then recovers
c)
The rate of the reaction increases
d)
The rate of the reaction is not affected
21.

The diagram shows some adjacent cells from the root of a plant. Which is the symplastic pathway of water movement?

a)

A

b)

B

c)

C

22.
What determines the rate of water movement from the roots to the leaves?
a)
absorption of water through the root hair cells
b)
development of a less negative water potential in the leaves
c)
diffusion of water through the stomata
d)
evaporation of water from the mesophyll cell walls
23.

The diagrams show where an inhibitor becomes attached to an enzyme and whether it is permanent or temporary. Which diagram represents a non-competitive inhibitor?

a)

1 and 2 only

b)

2 and 3 only

c)

3 and 4 only

d)

1, 2 and 3 only

24.

Polymers of molecule X or polymers of molecule Y can be formed using glycosidic bonds. Which statement is correct?

a)

Many of molecule X join to form amylose

b)

Many of molecule X join to form cellulose

c)

Many of molecule Y join to form amylopectin

d)

Many of molecule Y join to form glycogen

25.
Which process does not occur during the formation of messenger RNA?
a)
Condensation
b)
Polymerisation
c)
Replication
d)
Transcription
26.
How do single-celled organisms survive wihtout a specialise transport system?
a)
Their cell surface membranes are totally permeable
b)
They do not move very often
c)
They do not need to absorb oxygen
d)
They have a large surface area to volume ratio
27.
What occurs during movement of water through the apoplast pathway? (1) water enters cell wall (2) water enters cytoplasm through plasma membrane (3) water enters vacuoles (4) water moves from cell to cell through plasmodesmata (5) water moves from cell wall to cell wall through intercellular spaces
a)
1 and 5
b)
2 and 4
c)
1, 3 and 4
d)
2, 3 and 5
28.

The graph shows the dissociation of oxygen from haemoglobin at two different pHs. Which curve represent the lower pH and in which tissue might the data have been recorded?

a)

lower pH: curve 1. tissue: active muscle

b)

lower pH: curve 1. tissue: resting muscle

c)

lower pH: curve 2. tissue: active muscle

d)

lower pH: curve 2. tissue resting muscle

29.

The diagram shows the changes in pressure in the left side of the heart during the cardiac cycle. Which statement about the heart valves is correct?

a)

At P, the atrioventricular valve opens

b)

At Q, the semilunar valve opens

c)

At R the semilunar valves opens

d)

At S, the atrioventricular valve closes

30.

From the table, which row correctly shows all the blood vessels that have the features listed?

a)

A

b)

B

c)

C

d)

D

31.

Which row shows the effects of chronic bronchitis?

a)

A

b)

B

c)

C

d)

D

32.
Which reactions take place in the capillary in the lungs? (1) carbonic acid is formed from carbon dioxide and water (2) carbaminohaemoglobin is formed from carbon dioxide and haemoglobin (3) haemoglobinic acid is formed from haemoglobin and hydrogen ions (4) carbon dioxide and water are formed from hydrogen carbonate ions and hydrogen ions
a)
1 and 2
b)
3 and 4
c)
3 only
d)
4 only
33.

From the table, which changes to the water potential and the volume of liquid in the phloem occur when carbohydrate is taken out of a root into phloem sieve tubes?

a)

A

b)

B

c)

C

d)

D

34.
Some symptoms of COPD are listed (1) bursting of alveoli (2) increase in secretion of mucus (3) loss of elastic fibres (4) narrowing of airways (5) reduction in surface area for gaseous exchange. Which of these are also the symptoms of emphysema?
a)
1, 2 and 4
b)
1, 3 and 5
c)
2, 3 and 4
d)
2, 4 and 5
35.
What describes the function of a macrophage?
a)
They are found in tissues and secrete cytokines in response to infection.
b)
They can leave the blood and accumulate at sites of inflammation.
c)
They can leave the blood and secrete cytotoxins when exposed to damaged cells.
d)
They circulate in the blood and produce antigens in response to infection.
36.
Smallpox was eradicated from the human population by a worldwide preventative programme. Which type of immunity was triggered in people who were treated as part of this programme?
a)
Artificial active immunity
b)
artificial passive immunity
c)
natural active immunity
d)
natural passive immunity
37.
Which pathogens are spread by droplet infection? (1) Mycobacterium tuberculosis (2) Vibrio cholerae (3) Morbillivirus
a)
1, 2 and 3
b)
1 and 2 only
c)
1 and 3 only
d)
2 and 3 only
38.
The antibiotic penicillin prevents the formation of cross-links between peptidoglycans during bacterial cell wall synthesis by blocking the enzyme transpeptidase. Which statements describe the action of penicillin on bacteria? (1) It is an enzyme inhibitor. (2) It weakens the bacterial cell wall. (3) It will work at any stage during the bacterial life cycle.
a)
1, 2 and 3
b)
1 and 2 only
c)
1 and 3 only
d)
2 and 3 only
39.

With reference to the photomicrograph, what is the functions of tissues X and Y?

a)

X secretes mucus and Y prevents collapse of the airway

b)

X supports the airway and Y dilates the airway

c)

X traps dust and dirt and Y secretes mucus

d)

X waft dust and dirt upward and Y constrict airway

40.

Which flow diagram correctly describes the effect of tar entering the lungs?

a)
b)
c)
d)

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