The most important factor which governs diffusion of drugs across capillaries other than those in the brain is:

If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is:

The choline ester resistant to both true and pseudocholinesteraseis:

The organophosphates produce irreversible inhibitionof cholinesterase because:

Which of the following is a prodrug of adrenaline used topically in glaucoma:

High anticholinergic property is present in the following antihistaminic:

Tachyphylaxisto many actions on repeated injection is a feature of the following autacoid:

Choose the ergot alkaloid that is well absorbed orally, has weak vascular but prominent uterine stimulant action:

The following antitussive is present in opium but has no analgesic or addicting properties:

The rare but characteristic adverse effect of HMGCoAreductase inhibitors is:

Choose the correct statement(s) about inhaled glucocorticoids in chronic obstructive pulmonary disease (COPD):

Indications of somatostatin include:

Overtreatment with the following thyroid inhibitor results in enlargement of the thyroid:

The second generation sulfonylurea hypoglycaemicsdiffer from the first generation ones in that they:

Select the muscle relaxant that is used to control spasticity associated with upper motor neurone paralysis:

The following local anaesthetic raises BP instead of tending to cause a fall:

The following class of gastric antisecretory drug also reduce gastric motility and have primary effect on juice volume, with less marked effect on acid and pepsin content:

Select the drug that antagonises diazepam action noncompetitively:

The following antiepileptic drug is most likely to impair learning and memory, and produce behavioural abnormalities in children:

Select the antiparkinsonian drug which directly activates dopaminergic D2 receptors in the striatum:

Which of the following is an atypical neuroleptic drug:

Select the anxiolytic benzodiazepine that has additional mild antidepressant property:

Which antiemetic selectively blocks levodopa induced vomiting without blocking its antiparkinsonian action:

Strychnine produces convulsions by:

The following angiotensin converting enzyme inhibitor can reduce cardiac contractility:

Digoxin is contraindicated in:

Glyceryltrinitrate is used in CHF for:

The most significant feature of the antiarrhythmic action of lignocaine is:

Loss of taste sensation can be a side effect of the following antihypertensive drug:

The following drug is used to treat angioedema

Thiazide diuretics and furosemide have directionally

opposite effect on the net renal excretion of the

following substance:

Nonsteroidalantiinflammatory drugs reduce the diuretic action of furosemide by:

A patient of chronic renal failure maintained on intermittent haemodialysis has anaemia not responding to iron therapy. Which of the following additional drug is indicated:

Which fibrinolytic agent(s) selectively activate(s) fibrin bound plasminogen rather than circulating plasminogen: