WorksheetsSurface epithelial tumors of ovary
Total questions: 25
Worksheet time: 14mins
Arrange the following cancers in decreasing order of incidence:
A: Cervical cancer
B: Ovarian cancer
C: Endometrial cancer
A, B, C
A, C, B
B, A, C
C, A, B
Ovarian surface epithelial tumors are those which usually arise from the surface epithelium of the ovary and undergo neoplastic transformation
True
False
Which of the following is not a malignancy that occurs in the ovary?
Choriocarcinoma
Endometrioid carcinoma
Cystadenofibroma
Embryonal carcinoma
Type 2 ovarian neoplasms are most commonly:
Mucinous type
Serous type
Endometrioid type
Clear cell type
Which of the following is not a risk factor for producing serous ovarian carcinomas ?
Nulliparity
Oral contraceptives
BRCA1 mutation
Gonadal dysgenesis
Match these genes with their respective grades of serous carcinoma as low (L) or high (H)
1) RB
2) NF1
3) KRAS
4) TP53
L - 1
H - 2, 3, 4
L - 2, 3
H - 1, 4
L - 3
H - 1, 2, 4
L - 3, 4
H - 1, 2
KRAS mutation does not produce STIC
True
False
The gross anatomy of an ovarian solitary cyst shows conspicuous dense and closely packed papillary projections.
The specimen would show microscopical features of:
Budding
Psammoma bodies
Non-stratification
Multinucleation
Microscopic analysis of a tumor shows widespread invasion of the underlying stroma and marked nuclear atypia. The appropriate statement(s) regarding it is:
KRAS gene mutation is involved
Gross specimen would reveal hemorrhage and necrosis
Usually bilateral
Type 1 tumor
Organ involved in both hematogenous spread and loca spread in serous carcinoma:
Appendix
Liver
Stomach
Lungs
Which of the following statements regarding incidence of mucinous tumors is true?
Primary ovarian mucinous carcinomas constitute ~30% of all ovarian neoplasms
Mucinous tumors constitute less than 5% of all ovarian tumors
Mucinous tumor is rare in a 68 year old
About 15% are borderline
A recently married woman after giving birth to her first child came to the OP with complaints of a mass in her abdomen. She was a habitual smoker. Which of the following is most likely?
Serous adenofibroma
Mucinous cystadenoma
Serous cystadenocarcinoma
Pseudomyxoma peritonei
KRAS mutation is not involved in:
Mucinous tumors
Serous tumors
Endometrioid tumors
Brenner tumors
Minimum cell thickness of the epithelium seen in mucinous tumors:
3
4
5
2
False statement about pseudomyxoma peritonei:
Cystic implants on peritoneum
Develops due to mucocele
Mostly caused by primary tumors
Intestinal obstruction may be seen
Which of the following genes are not important in endometrioid tumor?
PTEN
ARID1A
CTNNB1
NF1
Endometriosis poses a higher risk for endometrioid tumors than carcinoma endometrium
True
False
Cells with eosinophilic cytoplasm and abundant glycogen are seen in:
Mucinous tumors
Clear cell tumors
Endometrioid tumors
Serous tumors
Mesonephroid tumors are usually bilateral and almost always malignant
True
False
Which of the following tumors are made of cells resembling that of the renal pelvis?
Brenner tumor
Clear cell tumor
Mucinous tumor
Serous tumor
Select the true statement from the following regarding the tumor with above histological appearance:
Usually bilateral
Nucleus resembles that of granulosa cell tumor
Cells and stroma are unusual
Shows endometrial glands
Vaginal bleeding is a usual finding with ovarian tumors
True
False
CA-125 is raised in:
Serous carcinomas
Endometrioid carcinomas
Endometriosis
Mucinous carcinomas
Select the tumors that are commonly benign:
Mucinous tumors
Clear cell tumors
Endometrioid tumors
Serous tumors
Atypical proliferative tumors show absence of stromal invasion
True
False
