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Path Quiz

Total questions: 50

Worksheet time: 25mins

Name
Class
Date
1.
Which bone tumour is associated with lifting of periosteum off bone producing the Codman triangle and a sunburst appearance on X-ray?
a)
Osteosarcoma
b)
Osteoma
c)
Ewing sarcoma
d)
Giant cell tumor
2.
Which of the following is a non modifiable risk factor for Coronay heart disease?
a)
Diabetes
b)
Smoking
c)
Hypertension
d)
Old age
3.
An 80-year-old woman has had no major medical problems, but she has never been physically active for most of her life. One day she falls out of bed and immediately notes a sharp pain in her left hip. She is subsequently unable to ambulate without severe pain. Radiographs show not only a fracture of the left femoral head, but also a compressed fracture of T10. Which of the following conditions is she most likely to have?
a)
Vitamin D deficiency
b)
 Acute osteomyelitis
c)
 Osteogenesis imperfecta
d)
 Osteoporosis
4.
Commonest histological finding in benign hypertension is -
a)
Proliferating endarteritis
b)
Necrotising arteriolitis
c)
Hyaline arteriosclerosis
d)
Cystic medial necrosis
5.
An 11-year-old boy has pain in his left leg that has persisted for 3 weeks. On physical examination his temperature is 37.9°C. A radiograph of the leg reveals a mass in the diaphyseal region of the left femur with overlying cortical erosion and soft tissue extension. A bone biopsy is performed and the lesion on microscopic examination shows numerous small round blue cells. Karyotypic analysis of these cells shows t(11;22). Which of the following neoplasms is he most likely to have?
a)
Osteoblastoma
b)
Ewings sarcoma
c)
neuroblastoma
d)
osteosarcoma
6.
Onion skin thickening of arteriolar wall is seen in -
a)
Malignant hypertension
b)
Benign hypertension
c)
Peripheral vascular disease
d)
None of the above
7.
Osteitis fibrosa cystica is seen in
a)
Osteomalacia
b)
Osteoporosis
c)
Hyperparathyroidism
d)
Rickets
8.
The most common site for myocardial infarction is -
a)
Left atrium
b)
Left ventricle
c)
Right atrium
d)
Right ventricle
9.
Most common organism that cause pyogenic osteomyelitis is
a)
E.coli
b)
Staphylococcus aureus
c)
Klebsiella
d)
Pseudomonas
10.
Irreversible injury in myocardium occurs at-
a)
2 minutes
b)
30 minutes
c)
2 hours
d)
5 hours
11.
Most common site for tuberculous osteomyelitis is
a)
spine
b)
pelvis
c)
humerus
d)
femur
12.
Earliest histological change in MI -
a)
Macrophage infiltration
b)
Neutrophilic infiltration
c)
Waviness of fibers
d)
Coagulative necrosis
13.
Renal osteodystrophy is characterized by
a)
hyperphosphataemia
b)
Hypocalcemia
c)
increased PTH secretion
d)
All of the above
14.
First enzyme to be raised in MI is -
a)
CPK-MB
b)
LDH
c)
Myoglobin
d)
Troponin-1
15.
Ewing's sarcoma arises from
a)
G-cells
b)
Totipotent cells
c)
Neuroectodermal cells
d)
neurons
16.
Troponin - T is a marker of -
a)
Renal diseases
b)
Muscular dystrophy
c)
Cirrhosis of liver
d)
Myocardial Infarction
17.
Small round blue cells seen in Ewing's sarcoma histologically, are filled with
a)
mucin
b)
iron
c)
fat
d)
Glycogen
18.
Autopsy finding after 12 hrs in a case of death due to MI -
a)
Caseous necrosis
b)
Coagulative necrosis
c)
Fat necrosis
d)
Liquifactive necrosis
19.
Giant cell tumor is seen at
a)
epiphysis
b)
metaphysis
c)
diaphysis
d)
none of the above
20.
Causative organism in acute bacterial endocarditis is -
a)
Staphylococcus aureus
b)
Streptococcus viridans
c)
Pneumococcus
d)
Streptococcus pyogenes
21.
Which lesion microscopically is composed of curvilinear trabeculae of woven bone lacking osteoblastic rimming and mimicing chinese letter & surrounded by moderately cellular fibroblastic proliferation
a)
osteoblastoma
b)
osteosarcoma
c)
fibrous dysplasia
d)
fibrous cortical defect
22.
Mitral valve vegetations do not embolise usually to -
a)
Brain
b)
Liver
c)
Spleen
d)
Lungs
23.
Most common primary malignant bone tumor is
a)
osteosarcoma
b)
chondrosarcoma
c)
giant cell tumor
d)
Ewing's sarcoma
24.
Coronary heart disease may manifest as all, except -
a)
Angina on effort
b)
Cardiomyopathies
c)
Myocardial Infarction
d)
Sudden death
25.
Which of the following is not an example of peripheral immunologic tolerance?
a)
   Anergy
b)
  Thymic deletion
c)
Suppression by regulatory T-cells
d)
  Antigen sequestration
26.
Medial calcification is seen in -
a)
Atherosclerosis
b)
Arteriosclerosis
c)
Monckeberg's sclerosis
d)
Dissecting aneurysm
27.
A 48-year-old woman has a malignant lymphoma involving lymph nodes in the para-aortic region. She is treated with a chemotherapeutic agent which results in the loss of individual neoplastic cells through fragmentation of individual cell nuclei and cytoplasm. Over several weeks, the size of the lymphoma decreases, as documented on abdominal CT scans. By which of the following mechanisms has her neoplasm primarily responded to therapy?
a)
Coagulative necrosis
b)
Apoptosis
c)
acute inflammation
d)
phagocytosis
28.
Concentric hypertrophy of left ventricle is seen in -
a)
Mitral stenosis
b)
Hypertension
c)
Aortic regurgitation
d)
None of the above
29.
Philadelphia chromosome is most commonly associated with which type of leukemia
a)
CML
b)
ALL
c)
AML
d)
CLL
30.
In myocardial infarction, microscopic picture of coagulative necrosis with neutrophilic infiltration is seen in -
a)
4-12 hrs
b)
12-24 hrs
c)
1-3 days
d)
3-7 days
31.
A 43-year-old man has complained of mild burning substernal or epigastric pain following meals for the past 3 years. Upper GI endoscopy is performed and biopsies are taken of an erythematous area of the lower esophageal mucosa 3 cm above the gastroesophageal junction. There is no mass lesion, no ulceration, and no hemorrhage noted. The biopsies demonstrate the presence of columnar epithelium with goblet cells. Which of the following mucosal alterations is most likely represented by these findings?
a)
atrophy
b)
hyperplasia
c)
dysplasia
d)
metaplasia
32.
Most accepted theory of atherosclerosis is -
a)
Lipid infiltration of intima
b)
Reaction to endothelial injury
c)
Due to smoking
d)
Hyperlipidemia
33.
An 80-year-old man dies from complications of Alzheimer disease. At autopsy, his heart is small (250 gm) and dark brown on sectioning. Microscopically, there is light brown perinuclear pigment with H&E staining of the cardiac muscle fibers. Which of the following substances is most likely increased in the myocardial fibers to produce this appearance of his heart?
a)
Hemosiderin resulting from iron overload
b)
Glycogen resulting from a storage disease
c)
Lipochrome from "wear and tear"
d)
Calcium deposition following necrosis
34.
Conditions included in left to right shunt are all except -
a)
Atrial Septal Defect
b)
Ventricular Septal Defect
c)
Patent Ductus Arteriosus
d)
Tetralogy Of Fallot
35.
Which type of leukemia is most commonly seen in children
a)
AML
b)
ALL
c)
CML
d)
CLL
36.
Features of tetralogy of fallot are all except -
a)
Aortic Displacement
b)
Pulmonary Stenosis
c)
ASD
d)
RV Hypertrophy
37.
Hemophilia A is due to deficiency of which clotting factor
a)
Factor VII
b)
Factor IX
c)
Factor VI
d)
Factor VIII
38.
Heart failure cells are stained by -
a)
Alcian blue
b)
Silver stains
c)
Prussian blue
d)
PAS
39.
Which neoplasm is most commonly seen in AIDS
a)
Kaposi's sarcoma
b)
B-cell lymphoma
c)
cervical carcinoma
d)
T-cell lymphoma
40.
Malignant HTN is marked and rapid increase of BP to -
a)
200/140
b)
120/80
c)
140/90
d)
90/60
41.
Manifestations of hypertensive retinopathy include -
a)
Widening and increase in diameter of vessels
b)
Cotton wool spots
c)
Rose spots
d)
Macroaneurysms
42.
Which bone tumour is associated with soap bubble appearance on X-ray?
a)
Osteosarcoma
b)
Osteoma
c)
Ewing sarcoma
d)
Giant cell tumor
43.
Flea bitten kidney is seen in -
a)
Acute glomerulonephritis
b)
Chronic glomerulonephritis
c)
Malignant hypertension
d)
Renal Cell Carcinoma
44.
Obstructive congenital heart disease includes -
a)
ASD
b)
VSD
c)
PDA
d)
Coarctation Of Aorta
45.
Vasospasm is the cause of -
a)
Stable angina
b)
Unstable angina
c)
Variant angina
d)
Classical angina
46.
Creatine kinase is elevated in MI after -
a)
2-4 hrs
b)
4-8 hrs
c)
12-24 hrs
d)
24 hrs
47.
Enzyme appearing last in MI is -
a)
CPK
b)
LDH
c)
SGOT
d)
SGPT
48.
Most common type of hypertension is
a)
Essential HTN
b)
Renal HTN
c)
Endocrine HTN
d)
Neurogenic HTN
49.
Effects of right sided heart failure include all except
a)
CVC Liver
b)
CVC Spleen
c)
CVC Lung
d)
Subcutaneous tissue edema
50.
Embolic complications of Infective Endocarditis include all except -
a)
Janeway lesions
b)
Osler nodes
c)
Mycotic aneurysm
d)
Splinter hemorrhages