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WorksheetsHypertension in Pregnancy & In General
Total questions: 45
Worksheet time: 23mins
Which IV antihypertensive drug commonly used to treat intrapartum severe range BPs is properly matched with its most notable side effects?
Hydralazine - fetal arrhythmia
Labetalol - neonatal tachycardia
Hydralazine - maternal tachycardia
Labetalol - neonatal rebound hypertension
For women with cHTN without SI PEC, when is delivery recommended
37/0 to 38/6
38/0-39/6
39/0-40/0
No guidelines
All except which of the following support the diagnosis of SI PEC?
Decreased platelet count
Increased serum creatinine
Elevated alkaline phosphate
Elevated AST
In addition to cHTN, which conditions are considered high risk for developing PEC?
Asthma
SLE
Hx of GDMA
Elevated maternal serum AFP
Which of the following medications is preferred for intrapartum prevention of eclampsia?
Phenytoin
Midazolam
Phenobarbital
Magnesium sulfate
Results from randomized controlled trials suggest what benefit is gained from low-dose aspirin use during
pregnancy in women with chronic hypertension?
No benefit
Reduced preterm birth rates
Reduced maternal mortality rates
Reduced fetal-growth restriction rates
Which of the following comorbidities is most frequently seen in pregnant women with chronic hypertension?
Hypothyroidism
Pre-gestational diabetes
Systemic lupus erythematosus
Antiphospholipid antibody syndrome
How should a patient whose blood pressure is 120/80 mm Hg at her annual examination be counseled?
Initiate 30 minutes of daily exercise
Limit alcohol consumption to two drinks per day
Start pravastatin to reduce her cardiovascular risk
Plan no recommendation as her blood pressure is normal
Which of the following blood pressure measurements meets the criteria for “prehypertension” as defined by
the Joint National Committee 7?
Diastolic blood pressure 70–80 mm Hg
Diastolic blood pressure 90–95 mm Hg
Systolic blood pressure 120–130 mm Hg
Systolic blood pressure 140–150 mm Hg
28-year-old G3P1102 at 9 weeks' gestation presents
for establishment of prenatal care. Her first pregnancy
was complicated by gHTN at term,
and her second was complicated by iatrogenic preterm
delivery at 36 weeks' gestation for preeclampsia. Her
blood pressure was normal at her postpartum visit
2 years ago but has not been assessed since. Today her
body mass index is 46 kg/m2 and her blood pressure
is 158/96 mm Hg. As instructed, she calls back 2 days
after her visit to report that blood pressures have been
in the 146-160/94-100 mm Hg range at home. In
addition to initiation of an amihypertensive agent,
what is the next step in management of her blood
pressure in this pregnancy?
Baseline serum creatinine
Renal ultrasound with Doppler
Baseline 24-hour urine collection for protein, creatinine
clearance, and urinary metanephrines
All of the above
For women with chronic hypertension, what additional factor further increases the risk?
Oligohydramnios
Maternal smoking
Multifetal gestation
Pregestational diabetes
A 32yo G2P1 is sent to LD&D @ 32 weeks with persistent BPs of 200/120. She has a known history of asthma requiring daily meds and cHTN which has been treated with methyldopa. The most appropriate IV med to control her BP is
Hydralazine
Labetalol
MgSO4
Nfiedipine
Sodium Nitroprusside
A 29yo G1P0 @ 31w with twin gestation is sent to L&D because of elevated BPs. On examination, her BP is 160/100, and she has 3+ proteinuria. Labs show a platelet count of 75k, AST/ALT 120/100, Cr of 1.0. Ultrasound shows both fetuses are appropriately grown and FHT is reactive. Most appropriate next step is
Steroid
Document fetal lung maturity
Expectant management until 34 weeks gestation
Immediate cesarean delivery
Plasmapheresis
A 34yo G4P3 @ 35 weeks presents to L&D reported decreased fetal movement. She recently moved to the area and has not yet established care. She has all of her OB records documenting her 3 prior cesarean deliveries, one of which was a prior classical cesarean at 28 weeks. Her medical history of significant for pregestational DM that is well controlled and the recent development of PEC w/o SF. Her current pregnancy is complicated by previa with accrete. EFW is at 20%. Based on her clinical findings, the indication for a repeat cesarean delivery before 36 weeks of gestation is
Diabetes
Placenta previa with Accreta
PEC
prior classical cesarean delivery
A 27yo G1 with a history of SLE presents at 34 weeks gestation. She reports abdominal pain, nausea, vomiting. Her BP is 150/94, HR 110, and Temp of 100.5F. FHT is reassuring. Urine dipstick shows 2+ protein. A bedside FS glucose is 50. While in triage, the patient becomes confused and disoriented. Lab test that best explains the patient's acute symptoms is
Ammonia
Bilirubin
CBC
Creatinine
Liver Enzymes
What is the underlying etiology for proteinuria that is seen with preeclampsia?
Increased capillary permeability
Increased renal artery resistance
Increased glomerular filtration rate
Increased systemic vascular resistance
All EXCEPT which of the following increase a woman’s predisposition to develop preeclampsia syndrome?
Obesity
Smoking
Nulliparity
Multiple gestation
The typical blood volume of a gravida at term is 4500 mL. In patients with preeclampsia, which of the
following would be the expected blood volume?
2500 mL
3200 mL
4500 mL
5000 mL
In patients with preeclampsia, limited blood volume expansion during pregnancy aects maternal cardiac
function by which mechanism?
Decreases preload
Increases afterload
Increases stroke volume
Decreases cardiac output
Which of the following leads to increased uric acid levels in patients with preeclampsia?
Increased tubular reabsorption
Increased placental production
Decreased glomerular filtration rate
All of the above
Your patient presents with a BP of 160/104 mm Hg, 3+ proteinuria, and RUQ pain at 36 weeks’ gestation. Following induction of labor, she delivers vaginally. She has
uterine atony, and her estimated blood loss is 1500 mL. Her serum creatinine rises from 0.98 mg/dL
predelivery to 1.42 mg/dL. What is the most likely explanation for this finding?
Postpartum hemorrhage
Severe preeclampsia alone
Subcapsular liver hematoma
Dehydration secondary to prolonged induction
TheCT is obtained on a postpartum hypertensive patient with confusion. Cerebral edema was diagnosed. All EXCEPT which of the following are indicated treatments in the
management of the patient:
Mannitol
Dexamethasone
Intravenous immune globulin
Antihypertensive medication
Your patient is admitted to the hospital for evaluation of new-onset hypertension at 30 weeks’
gestation. The patient has blood pressures of 140–150/85–100 mm Hg during the next 5 days. Which of the
following should prompt consideration for premature delivery?
Headache
Worsening pedal edema
3+ proteinuria on dipstick
Fetal biophysical profile score of 8
Your obstetrical is admitted to the hospital for evaluation of new-onset hypertension at 30 weeks’
gestation. Three days after admission, the patient develops severe preeclampsia and delivery is indicated.
Sonographic evaluation reveals a cephalic presentation and estimated fetal weight of 1405 g. If labor
induction is attempted, what is the approximate rate of successful vaginal delivery?
10%
30%
50%
80%
What salutary effect does dexamethasone possibly have when used in the treatment of HELLP (hemolysis,
elevated liver enzymes, low platelet count) syndrome?
Decreased maternal mortality rate
Decreased rate of acute renal failure
Faster aspartate transferase recovery time
Increased platelet count in severe thrombocytopenia
An eclamptic patient who has received a 4-g loading dose of magnesium sulfate has another seizure. Which
of the following medications can be given as adjuvant anticonvulsant therapy?
Midazolam
Thiopental
Additional magnesium sulfate
All of the above
What is the target magnesium level when used for eclampsia prophylaxis?
2.0–3.5 mg/dL
5-9 mg/dL
8.4–10.4 mg/dL
None of the above
A pregnant patient has a seizure at home and is evaluated by an emergency room physician. He consults with
a neurologist who, after excluding other etiologies for the seizure, makes the diagnosis of eclampsia. The
neurologist recommends phenytoin for eclampsia prophylaxis to the on-call obstetrician. What is the best
response to this recommendation?
Agree and load the patient with phenytoin
Give intravenous loading dose of magnesium sulfate and oral phenytoin
Explain there is a reduction of recurrent seizure activity with magnesium sulfate and start magnesium
sulfate
None of the above
Antenatal use of nitroglycerin to control severe maternal hypertension can lead to which of the following
complications?
Fetal acidosis
Fetal oliguria
Fetal cyanide toxicity
Reduced fetal heart rate variability seen during monitoring
Preeclampsia is a marker for all EXCEPT which of the following morbidities later in life?
Metabolic syndrome
Chronic renal disease
Ischemic heart disease
Nonalcoholic steatohepatitis
A 29-year-old woman, gravida 1, at 31 weeks of gestation with a twin gestation is sent to the
labor and delivery unit because of elevated blood pressure. On examination, her blood pressure
is 160/100 mm Hg and she has 3+ proteinuria. Laboratory evaluation reveals a platelet count of
75,000 mm3, aspartate aminotransferase of 120 international units/L, alanine aminotransferase
of 110 international units/L, lactate dehydrogenase of 800 international units/L, creatinine of
1.0 mg/dL, and a fibrinogen of 300 mg/dL. Ultrasonography reveals that both fetuses are appropriately
grown and the fetal heart tracings are reassuring. The most appropriate next step is
corticosteroid administration
documentation fetal lung maturity
expectant management until 34 weeks of gestation
immediate cesarean delivery
plasmapheresis
A 29-year-old woman, gravida 1, presents to your office with a known triplet gestation at 12 weeks of gestation after ovulation induction with clomiphene. She declines multifetal pregnancy reduction. The intervention most likely to improve her pregnancy outcome is
decreased activity
administration of vitamin E
administration of low-dose aspirin
prophylactic cerclage
Mykena
A 24-year-old woman whose last menstrual period was 6 weeks ago presents to the emergency department reporting nausea for the past week and heavy vaginal bleeding for the past 24 hours. Her blood pressure is 140/90 mm Hg, and her heart rate is 120 beats per minute. Physical examination demonstrates a 12-week size uterus and a cervix that is long and closed. Serum β-hCG is
400,000 mIU/mL. Pelvic ultrasonography demonstrates intrauterine tissue with a diffuse mixed echogenic pattern without a distinct placenta and no evidence of fetal tissue. The most likely diagnosis is
early pregnancy loss
early pregnancy loss
gestational trophoblastic disease
twin gestation
A patient comes to your office at 28 weeks of gestation for her 1-hour glucose tolerance test. A
complete blood count is done at the same time. Her platelet count is 95,000/mm3. A repeat platelet
count 6 weeks later is 92,000/mm3. She currently feels well with no recent illnesses. She is healthy
and takes only a prenatal vitamin. Her initial prenatal laboratory results show a platelet count of
287,000/mm3. She has normal blood pressure and her urine dipstick test result is negative for protein.
The most likely diagnosis is
preeclampsia
gestational thrombocytopenia
idiopathic thrombocytopenia purpura
drug-induced thrombocytopenia
thrombocytopenia due to a viral illness
A 30-year-old primigravid woman comes to your office for her first prenatal visit at 12 weeks of
gestation. She has mild hypertension that has been treated with pharmacotherapy for the past year.
She reports first-trimester exposure to an angiotensin converting enzyme (ACE) inhibitor. Her renal
function is normal and she had a negative screen result for diabetes mellitus in the past year. The
most appropriate next step to identify fetal abnormalities associated with ACE inhibitor therapy is
karyotype
nuchal translucency
second-trimester serum screening
targeted ultrasonography
A 26-year-old primigravid woman at 36 weeks of gestation has a platelet count of 62,000/mm3
noted on routine blood work. She does not have a history of thrombocytopenia, easy bruising, menorrhagia,
rash, or joint ache. She has a history of Raynaud phenomenon and chronic hypertension.
Her only medication is prenatal vitamins. Her first-trimester laboratory results include a negative
human immunodeficiency virus (HIV) test and a platelet count of 104,000/mm3. Her blood pressure
is 138/86 mm Hg and she has trace protein in her urine. Her hemoglobin and transaminase levels
are normal. Physical examination is significant for mild pedal edema. The diagnosis that most
likely explains her thrombocytopenia is
gestational thrombocytopenia
immune thrombocytopenic purpura
preeclampsia
systemic lupus erythematosus
A 36-year-old woman, gravida 1, para 0, at 32 weeks of gestation with known systemic lupus
erythematosus (SLE) comes to your office for a routine prenatal visit. She has lupus nephritis
with 2 g of protein in 24 hours. Her pregnancy has thus far proceeded normally although she has
experienced mild arthritic symptoms with pain and discomfort in her joints. She has been taking
no medication for her SLE other than nonsteroidal anti-inflammatory drugs. She is now experiencing
headache and increased pedal edema (+3). She is found to have hypertension (blood pressure
150/100 mm Hg) and her temperature is 38.1°C (100.6°F). Her laboratory results show a hemoglobin
level 10.2 g/dL, platelet count 160,000/mm3, glucose level 98 mg/dL, and an increased 24-hour
urinary protein of 4 g. Her levels of ammonia, liver enzymes, lactate dehydrogenase, and bilirubin
are all in the normal range. The most likely diagnosis is
hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome
thrombotic thrombocytopenia purpura (TTP)
hemolytic uremic syndrome (HUS)
exacerbation of SLE
acute fatty liver of pregnancy
A 30-year-old multiparous woman with a history of chronic hypertension discontinued her usual
medications when she learned she was pregnant. At her prenatal visit at 22 weeks of gestation,
her blood pressure (BP) is 148/90 mm Hg. Urine dipstick shows no protein. She reports no other
medical problems. The best next step in her management is
no medication
methyldopa
labetalol
um sulfate
A 19-year-old nulligravid woman at 34 weeks of gestation comes to your clinic for a prenatal visit. Her blood pressure (BP) to this point has been in the range of 100–110 mm Hg (systolic) over 60–70 mm Hg (diastolic). She is experiencing normal fetal movements and reports no health issues; her BP at this visit is 146/93 mm Hg. Physical examination is otherwise unremarkable. Fetal heart rate is 140 beats per minute. Urine dipstick is negative for protein. Estimated fetal weight is 2,288 g (43rd percentile). She returns 3 days later for another prenatal visit, at which time her BP
is 150/92 mm Hg. A 24-hour urine collection result shows 100 mg of protein in the urine. Platelets are 202,000/mm3. Serum alanine aminotransferase is 20 units/L. Serum aspartate aminotransferase is 23 units/L. The most appropriate next step in management is
corticosteroids
magnesium sulfate
oral labetalol
continued expectant management
A 32-year-old woman, gravida 2, para 0, at 30 weeks of gestation with a dichorionic twin gestation presents with nausea and vomiting, right upper quadrant pain, and moderate vaginal bleeding. She has not experienced contractions or vaginal fluid leak. On examination, her blood pressure (BP) is 152/100 mm Hg and she appears in moderate distress with hyperreflexia and pitting edema of the lower extremities. Fetal tracing is reactive for both twins. Laboratory results show a platelet count
of 64,000/mm3, aspartate aminotransferase of 320 international units/L, alanine aminotransferase
of 280 international units/L, creatinine of 1.3 mg/dL, lactate dehydrogenase of 700 international units/L, fibrinogen of 80 mg/dL, and prothrombin time of 18 seconds. In addition to administration of steroids, the most appropriate next step is
delivery after completion of fetal lung maturity
delivery at 34 weeks of gestation
delivery after completion of steroids administration
immediate delivery
A patient has a blood pressure of 110/72 mm Hg on her first prenatal visit at 8 weeks’ gestation. She develops
hypertension in the third trimester, and at delivery, her blood pressure is 148/94 mm Hg. Urine protein by
dipstick is trace, her creatinine level is 0.76 mg/dL, and her hypertension has resolved by the time of her
hospital discharge. What is her correct diagnosis?
Preeclampsia
Chronic hypertension
Gestational hypertension
Superimposed preeclampsia
A patient with antepartum baseline blood pressure measurements of 90/65 mm Hg has blood pressures of
130–140/80–86 mm Hg at delivery. She has an increased risk of which of the following obstetric
complications?
Eclampsia
Placental abruption
Nonreassuring fetal heart rate tracing
None of the above
In a low-risk population, treatment with which of the following medications resulted in a reduced incidence
of preeclampsia?
Aspirin
Pravastatin
Hydrochlorothiazide
None of the above
In studies evaluating the antenatal use of labetalol for treatment of early mild preeclampsia, which of the
following is reduced?
Blood pressure
Fetal-growth restriction
Length of inpatient hospitalization
All of the above
What clinical sign or test can be used to detect hypermagnesemia prior to development of respiratory
depression?
Heart rate
Patellar reflex
Presence of clonus
Visual field testing
