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Endocrinologia - The MASK

Total questions: 40

Worksheet time: 20mins

Name
Class
Date
1.

All the following hormones have receptors on the plasma membrane of target tissues except :-

a)

Thyrotropin

b)

Glucagon

c)

Estradiol

d)

Epinephrine

2.

Which of the following molecules is used for cell signaling?

a)

CO2

b)

O2

c)

N2

d)

NO

3.

Which of the following is not stored in cell?

a)

Insulin

b)

Cortisol

c)

Thyroxin

d)

Renin

4.

Which of the following acts through Tyrosine-kinase receptor?

a)

Glucagon

b)

GH

c)

FSH

d)

Insulin

5.

All are second messengers except :-

a)

Guanylyl cyclase

b)

cAMP

c)

IP3

d)

DAG

6.

This is adrenal gland. Hormone produced by the marked area A is :-

a)

Aldosterone

b)

Cortisol

c)

Androgen

d)

Epinephrine

7.

Chronic Atrophy of adrenal gland will result in which hormone deficiency?

a)

CRH

b)

ACTH

c)

Cortisol

d)

MSH

8.

Stress-induced hyperglycemia is due to:-

a)

Glucocorticoids

b)

Nor-epinephrine

c)

Thyroxine

d)

Insulin

9.

ACTH level is high during:-

a)

Early Morning

b)

Evening

c)

Afternoon

d)

Night

10.

Which hormone does not increase in burns?

a)

Cortisol

b)

LH

c)

Glucagon

d)

Epinephrine

11.

Common precursor of Mineralocorticoids, Glucocorticoids and Sex steroids is?

a)

Pregnenolone

b)

α-hydroxyprogesterone

c)

Dehydrotestosterone

d)

Deoxycorticoid

12.

Hyperaldosteronism is associated with all except :-

a)

Hypernatremia

b)

Hypokalemia

c)

Hypertension

d)

Metabolic Acidosis

13.

Vasomotor reversal of dale is demonstrated by :-

a)

Fall in BP by high dose intravenous Ach

b)

Increase in BP following Administration of IV propanolol

c)

Fall in BP by ganglionic blocker

d)

Fall in BP by adrenaline pretreated with phentolamine

14.

Conn Syndrome is seen due to increased production of :-

a)

Cortisol

b)

ACTH

c)

CRH

d)

Aldosterone

15.

Drugs useful in treatment of Cushing's Syndrome is :-

a)

Aminoglutethimide

b)

Mitothane

c)

Ketoconazole

d)

All of the above

16.

True about intracellular receptors is :-

a)

Mainly on nuclear surface

b)

Steroids act on them sometimes

c)

Estrogen doesn't act on it

d)

GH act on it

17.

Hormones which are under inhibitory control of hypothalamus :-

a)

Prolactin

b)

GH

c)

Prolactin only

d)

Both Prolactin and GH

18.

Continuous Administration of GnRH :-

a)

Stimulates Hypothalamic-Pituitary Axis

b)

Suppresses Hypothalamic-Pituitary Axis

c)

May suppress or stimulate Hypothalamic-Pituitary Axis

d)

Has no effect on Hypothalamic-Pituitary Axis

19.

Posterior Pituitary secretes :-

a)

Prolactin

b)

ADH

c)

MSH

d)

FSH

20.

All of the following stimulate GH release except :-

a)

Fasting

b)

Free Fatty Acids

c)

Exercise

d)

Stress

21.

Wolf Chaikoff effect is due to :-

a)

Suppression of TSH secretion

b)

Decreased iodination of MIT

c)

Decreased T3 to T4 conversion

d)

Iodine Intake

22.

Sodium Iodide Symporter is not present in :-

a)

Pituitary

b)

Thyroid

c)

Placenta

d)

Parotid

23.

Prolactin level in blood is :-

a)

20 mg/mL

b)

20 ng/mL

c)

20 mg/L

d)

20 ng/L

24.

Acromegaly is due to excess of :-

a)

GH

b)

Insulin

c)

Adrenaline

d)

Somatomedin

25.

In thyroid-follicle for how long is thyroxine stored ?

a)

2-3 weeks

b)

2-3 days

c)

2-3 months

d)

2-3 years

26.

Identify the hormone :-

a)

GH

b)

Cortisol

c)

Insulin

d)

Estrogen

27.

Insulin like growth factor (Somatomedin) is secreted by :-

a)

Liver

b)

Pituitary

c)

Pancreas

d)

Adrenal Gland

28.

Insulin resistance downregulates :-

a)

GLUT-1

b)

GLUT-2

c)

GLUT-3

d)

GLUT-4

29.

In fetus, Insulin Secretion begins by :-

a)

3rd month

b)

5th month

c)

7th month

d)

9th month

30.

Mutation in GLUT-2 causes :-

a)

Dandy Walker Syndrome

b)

Fanconi Bickel Syndrome

c)

Beckwith Syndrome

d)

Menke's Discase

31.

Insulin is essential for Glucose into :-

a)

All tissues

b)

Renal Tubular Cells

c)

Mucosa of Small Intestine

d)

Skeletal muscle

32.

In a seriously ill patient, addition of amino acids in diet results in a positive nitrogen balance. The mechanism for that is :-

a)

Increased GH secretion

b)

Enhanced rate of gluconeogenesis

c)

Increased absorption of amino acids from diet

d)

Increased Secretion of Insulin

33.

Insulin can be indirectly measured with the help of :-

a)

C Peptide

b)

A Peptide

c)

Blood Glucose

d)

Glucagon

34.

Osteoclasts are inhibited by :-

a)

Parathyroid Hormone

b)

Calcitonin

c)

1,25-dihydroxycholecalciferol

d)

Tumor necrosis factor

35.

Which of the following organ is not involved in Calcium Homeostasis?

a)

Kidneys

b)

Intestines

c)

Skin

d)

Lungs

36.

Site of hydroxylation of cholecalciferol is :-

a)

Kidney

b)

Skin

c)

Liver

d)

Lung

37.

Form of Vit.D which is measured in serum is :-

a)

Cholecalciferol

b)

25-hydroxyvitamin D

c)

1,25-dihydroxyvitamin D

d)

24,25-dihydroxyvitamin D

38.

Which of the following is a rate limiting step?

a)

1.

b)

2.

c)

3.

d)

None of the Above

39.

A small Ca binding protein that modifies the activity of many enzymes and other proteins in response to changes of Ca concentration, is known as :-

a)

Cycline

b)

Calmodulin

c)

Collagen

d)

Kinesin

40.

Various cells respond differentially to a second messenger (such as increased cAMP) because they have different :-

a)

Receptors

b)

Enzymatic Composition

c)

Nuclei

d)

Membrane Lipid

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