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WorksheetsAnti infectives part 1
Total questions: 29
Worksheet time: 15mins
Anti infectives are for the following, EXCEPT:
Blepharoconjunctivitis
Glaucoma
Superficial punctate keratitis
Papillary conjunctivitis
Antibiotics are marketed as the following, EXCEPT :
combination of 2 ingredients
one active ingredients
an NSAID and an active ingredient
A steroid and active ingredient
The following are resistance mechanism to an antibiotics, EXCEPT
Active Efflux
Active uptake of drugs by the bacteria
Alteration of drug binding sites
production of inactivation enzyme
the following are ways to avoid microbial resistance, EXCEPT:
used antiB excessively
Use the latest antiBs
use a second therapeutic agent
use when need only
The following are the classification of antibacterial by Ms Uma, EXCEPT :
cell wall
protein synthesis
bacterial DNA
Bacterial primary metabolism
The following are beta lactams antibiotics, EXCEPT:
Bacitracin
Penicillin
Cephalosporin
Carbapenems
Which of the following penicillin have anti pseudomonal activity?
piperacillin
ampicillin
amoxicillin
Cloxacillin
Following are Adverse Effects of Cephalosporins, EXCEPT:
minor rash
Diarrhea
Ototoxicity
Bleeding tendencies
All glycopeptides antibiotics are
bacteriostatis
Bactericidal
excellent against Gram negative
Inactive against Gram postive
Polymixin B's mode of action ?
disrupt cell wall synthesis
disrupt intermediate metabolism
disrupts protein synthesis
disrupts cell membrane synthesis
Tetracyclines binds to which ribosome subunit
90S
50s
30s
20S
Which of the following is the side effect of Tetracyclines
dropping/ loosing hair
slow bone growth
crackingof nails
graying of teeth
Erythromycin is a macrolide which disrupts __________.
protein synthesis
cell membrane
cell wall
intermediate metabolism
Erythromycin is an excellent agent for
intravitreal injection
hepatitis B patient
Active therapy
pressure patching corneal abrasions
what is the brand name for Azithrimycin (1%gtt)
AzithSite
AzoSite
AziSite
AzaSite
Which of the following is an excellent agent for corneal penetration
Bacitracin
Chloramphenicol
Polymixin B
Tetracyclines
Chloramphenicol is not effective against which of the following
Haemophilus Spp
Chlamydiae
Pseudomonas Aeruginosa
Rickettsiae
The preservative used in Chloramphenicol preparation is
Sodium Nitrate
Phenylmercuric nitrate
Benzalkonium Chloride
Benzoic Acid
Polyfax is a combo drug of which of the following
polymixin B + Trimethoprim 0.1%
polymixin B + Trimethoprim 0.5%
polymixin B + Bacitracin 500units
polymixin B + Bacitracin 1000units
which of the following is not an Aminoglycoside drug
Gentamycin
Neomycin
Tobramycin
Ofloxacin
What kind of toxicity is normal observed with aminoglycoside drugs?
Ototoxicity
Neurotoxicity
Orthotoxicity
gastrotoxicity
which of the following composition derives Neosporin gtt?
Neomycin +gramicidin + polymixin B
Neomycin +gramicidin + polymixin A
Neomycin + dexamethasom + polymixin B
Neomycin + betamethasone + polymixin B
Garasone is a combination of
Gentamicin + polymixin B
Gentamicin + Dexamethasone
Gentamicin + Gramicidin
Gentamicin + Betamethasone
Aminoglycosides can usually cause ocular surface toxicity such as
increase in IOP
Punctate keratitis
Corneal edema
Corneal infiltrates
ficudic acid inhibits protein synthesis by
binding to 50s ribosomes
binding to 30s ribosomes
blocking the enzymes for elongation
blocking the mRNA
Fucidic acid is not recommended for acute conjunctivitis in children because
it produces alot of side effects
it is not compliance
it is not effective against Gram postive bacteria
it is not effective against Gram negative bacteria
Which of the following drugs are not the latest Fluoroquinolones
Gatifloxacin
Levofloxacin
Besifloxacin
Moxifloxacin
which of the fluoroquinolones are a safer drug compared to the other
Ocuflox
Vigamox
Cravit
Zymar
Which of the following is NOT the adverse reaction of Ofloxacin
Tendon ruptures
numbness in the feet
loss of balance
aplastic anemia
