WorksheetsGeneral Pharmacology Quiz
Total questions: 20
Worksheet time: 11mins
The image shows Log DRC for drugs A,B,C,D. Which of these statements is true?
Drug A is most efficacious
Drugs B and C are equipotent
Drug D is most effective
Drug B is less potent than A
Arrange in the correct sequence of extent of absorption of a drug given by topical route. (max first, min last)
A: Scrotal
B: Posterior auricular
C: Dorsum of Hand
D: Scalp
E: Sole of foot
BADCE
BDACE
BADEC
BDAEC
Ceiling effect of a drug can be assessed during which phase of clinical trials?
1
2
3
4
Which of these is NOT a microsomal enzyme inhibitor?
Azithromycin
Clarithromycin
Erythromycin
Spiramycin
A 30 year old gentleman is a known case of Nephrotic syndrome. Protein binding of which of the following drug will not be affected?
Tolbutamide
Morphine
Diazepam
Valproate
Which route of drug administration avoids first pass metabolism and is used with drug preparation that releases drug slowly as long as seven days?
Topical
Transdermal
Sublingual
Oral
Which of these drug may require adjustment of doses in chronic liver disease as it releases an active product only after hepatic metabolism?
Lisinopril
Enalapril
Chlorpromazine
Dopamine
If Gs-alpha 1 gain of function mutation, which of these would happen?
Decreased cAMP
Decreased IP3`
Increased GTPase activity
Increased cAMP
For TDM to be clinically useful, following criteria has to be fulfilled:
A good relationship between plasma concentration and drug dosage
A poor relationship between plasma concentration and therapeutic response and/or toxicity
Pharmacodynamic tolerance is suspected
Clinical response cannot be easily monitored
After giving an enzyme inhibitor, if Vmax decreases to 60% and Kmax is same as before. Which type of inhibition is this?
Competitive equilibrium type
Competitive non-equilibrium type
Non-competitive
Un-competitive
The meaning of 'Store in a cool place' written over
a strip of medicine is that it should be kept between
temperature of:
2 to 8 degree Celsius
8 to 15 degree Celsius
below freezing point of water
Zero degree Celsius
For which of the following drugs a warning is written
'To be sold by retail on the prescription of a Registered
Medical Practitioner only'?
Schedule H
Schedule x
Schedule Y
Schedule J
Absorption of which of the following increased
when given with a fatty meal?
Amphotericin B
Griseofulvin
Ampicillin
Aspirin
Side effects of a drug arise due to interactions of the
drug to molecules other than the target. These effects of
the drug can be minimized by its high:
Specificity
Solubility
Affinity
Hydrophobicity
Type B adverse drug reaction is:
Augmented effect of the drug
Allergic effect of the drug
Effect seen on chronic use of the drug
Delayed effect of the drug
Which of the following is the most accurate method for
calculating drug dosage in children:
Weight of the child
Weight of the child and adult dose
Age of the child
Body surface area
Which of these is an example where adverse effect of a drug is used for therapeutics?
Propranolol in Migraine
Nifedipine in Migraine
Metoclopramide in lactation failure
Minoxidil in alopecia areata
A drug having half life of 12 hours is administered orally twice a day. A graph is plotted between plasma drug
concentration and time which is shown in the graph. How much time will be taken for the plasma concentration to
reach at point A?
12 hrs
24 hrs
36 hrs
60 hrs
Expiry date shown in the strip of the tablet means:
If this preparation is used after Jul 2017, it will lose its potency
If this preparation is used after Jul 2017, it will become toxic
Quality of this medication is not assured after July 2017
Both a and B
What does IP stand for in this given image?
Drug is meant for Intra Pulmonary use
Intellectual Property right of the CIPLA
The standards according to Indian Pharmacopeia
It is an Instant release Preparation
