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WorksheetsANTI ANGINA DRUGS
Total questions: 10
Worksheet time: 10mins
Which drug is given to patients with angina who are treated with nitrates to help prevent reflex tachycardia?
Propanolol
Ranolazine
Nifedipine
Verapamil
Sotalol
Nitrates are converted to nitrite ions and then to nitric oxide. Nitric oxide activates guanylate cyclase and increases (X). Elevated (X) leads to dephosphorylation of myosin light chain resulting in smooth muscle relaxation. What is X?
(a)
Which of the following nirates has the earliest onset of action?
Oral isosorbide mononitrate
Sublingual ntroglycerin
Sublingual isosorbide mononitrate
Transdermal nitroglycerin
Which of the following drugs are calcium channel blockers used in the treatment of angina? (multiple right answers)
Nifedipine
Ranolazine
Verapamil
Diltiazem
Which of the following are absolute contraindications for beta-blockers? (multiple right answers)
Asthma
Uncontrolled diabetes mellitus
Critical limb ischaemia
Raynaurd syndrome
Cardiogenic shock
Beta-blockers therapy in angina should not be stopped abruptly and should be gradually tapered off over 2-3 weeks to avoid (X), myocardial infarction and hypertension. What is X?
(a)
Which of the following drugs are more useful in variant angina?
Verapamil
Diltiazem
Nifedipine
Metoprolol
A patient with angina is treated with metoprolol, isosorbide mononitrate and verapamil. However, his symptoms still persists. Which of the following drugs should be considered next?
Nitrogylcerin
Sotalol
Ranolazine
Procainamide
Amiodarone
Principles of treatment of acute coronary syndrome are:
to relieve the pain
to reduce workload of the heart
to improve tissue perfusion
to prevent complications
Why is it advisable to have a "nitrate free interval" for patients on long term nitrate therapy for angina?
to avoid toxicity
to promote drug clearance
to enhance drug distribution
to avoid tolerance
