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RECOMBINANT DNA TECHNOLOGY 2.0

Total questions: 21

Worksheet time: 21mins

Name
Class
Date
1.

  1. What is the function of the restriction enzyme for the bacteria themselves?

a)

to cut their own DNA

b)

to cut the invaded DNA

c)

to cut open the plasmid

2.

Choose the restriction enzyme that can do this

a)

SmaI

b)

PovII

c)

BamHI

d)

HaeIII

3.

The function of restriction enzyme is to recognize and cut the specific sequence called (a)  

4.

the same restriction enzyme must be used to produce (a)   ends.

5.

the capacity of the DNA fragment is 10 kb. Choose TWO vectors that can be used

a)

sCOS-1

b)

pUC18

c)

λ2001

d)

pYAC

6.

a DNA from hummingbird cell is cut at 10 recognition sites. How many fragments produced?

a)

10

b)

20

c)

11

d)

21

7.

a DNA from humming bird is cut at 10 recognition site. How many fragment contains gene of interest?

a)

10

b)

11

c)

1

d)

0

8.

Which of the following gene in the following plasmid having restriction site within to cut open the plasmid?

a)

AmpR

b)

ori

c)

lacZ

9.

choose the he sequence of sticky/ staggered end based on the diagram.

a)

GCTTAA

b)

CTTAA

c)

TTAA

10.

Choose the enzyme that can be used to seal the seal between plasmid and the inserted DNA fragment is

a)

Taq polymerase

b)

DNA ligase

c)

EcoRI

d)

SmaI

11.

the uptake of the recombinant plasmid into the host cell is called

a)

insertion

b)

transformation

c)

amplification

d)

isolation

12.
Which is true about plasmids?
a)
Plasmids can be cut at specific sequences called restriction sites.
b)
Plasmids contain a promoter sequence that defines where transcription begins.
c)
Plasmids can contain an antibiotic resistance gene.
d)
All of the statements are true about plasmids.
13.
Which of the following is a protein that acts as DNA scissors?
a)
plasmid
b)
restriction enzyme
c)
ligase
d)
protein expression
14.
Which of the following is an enzymatic protein that acts as DNA glue?
a)
plasmid
b)
restriction enzyme
c)
ligase
d)
protein expression
15.

The unpaired nucleotides produced by the action of restriction enzymes are referred to as

a)

sticky end.

b)

base sequence.

c)

blunt end

d)

restriction fragments.

16.

Which of the following palindromic base sequence identify by EcoRI

a)

5' GATTTC 3'

b)

5' GATTCC 3'

c)

5' GAATCC 3'

d)

5' GAATTC 3'

17.
Which woud require the use of recombinant DNA?
a)
Engineering bacteria to produce insulin
b)
Crossing 2 varieties of apple
c)
Breeding a donkey and horse to make a mule
d)
Creating a polyploid banana tree
18.

What is the name of an enzyme use in Polymerase Chain Reaction (PCR)?

a)

reverse transcriptase

b)

Taq polymerase

c)

primase

19.
Bacteria use restriction enzymes to protect themselves from:
a)
other bacteria
b)
plants
c)
antibiotics
d)
viruses
20.
A ____________ is required to transfer genes from one organism to another.
a)
vector
b)
reverse transcriptase
c)
transport molecule
d)
genetic probe
21.

During insertion step,

a)

The recombinant plasmid is inserted into a host cell

b)

The gene of interest is inserted into a plasmid

c)

The plasmid is inserted into the gene of interest