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Cell Cycle Control

Total questions: 20

Worksheet time: 12mins

Name
Class
Date
1.

Which molecules act as gatekeepers for each checkpoint of the cell cycle?

a)

p53 gene

b)

cyclins and cycline-dependent kinases

c)

thyroid hormones

2.

What is the purpose the the cell cycle checkpoints?

a)

To repair damaged cells before they enter cell division.

b)

To remove damaged cells from an organism.

3.

How many cell cycle checkpoints are there?

a)

1

b)

2

c)

3

d)

4

4.

What is the first checkpoint of the cell cycle?

a)

Mitosis checkpoint

b)

G1 checkpoint

c)

G2 checkpoint

5.

When is apoptosis initiated?

a)

When DNA damage is repaired.

b)

When cells are removed from the cell cycle.

c)

When DNA damage cannot be repaired.

6.
Uncontrolled cell division is stopped by...
a)
tumor suppressor genes
b)
oncogenes
7.
Which is an example of a tumor suppressor gene?
a)
apoptosis
b)
proto-oncogenes
c)
p53
d)
oncogenes
8.
p53 activates which of the following?
a)
Tumor suppressor genes
b)
cell cycle
c)
DNA repair proteins
d)
uncontrolled cell division
9.
This is the cell cycle checkpoint that makes sure environmental conditions are ideal for cell survival.
a)
G1 Checkpoint
b)
G2 Checkpoint
c)
M Checkpoint
d)
I Checkpoint
10.
This is the cell cycle checkpoint that makes sure DNA has been replicated correctly during S phase.
a)
G1 Checkpoint
b)
G2 Checkpoint
c)
M Checkpoint
d)
I Checkpoint
11.
This is the cell cycle checkpoint that makes sure the correct number of chromosomes are present and attached to microtubules.
a)
G1 Checkpoint
b)
G2 Checkpoint
c)
M Checkpoint
d)
I Checkpoint
12.
The checkpoints that regulate the cell cycle can fail when ____ becomes damaged.
a)
DNA 
b)
Cell Membrane
c)
Mitochondria
d)
Ribosomes
13.

Name the 3 checkpoints of the cell cycle

a)

Anaphase checkpoint, mitosis/metaphase checkpoint, and telophase checkpoint

b)

Interphase checkpoint, S phase checkpoint, and M phase checkpoint

c)

G1 checkpoint, G2 checkpoint, and S phase checkpoint

d)

G1 checkpoint, G2 checkpoint, and mitosis/metaphase checkpoint

14.

A disorder in which some of the body's cells lose the ability to control growth.

a)

growth factor

b)

human growth hormone

c)

cancer

d)

tumor

15.

Proteins that direct cells to speed up or slow down the cell cycle.

a)

growth factor

b)

human growth hormone

c)

cancer

d)

tumor

16.

Which one of these is characteristic of cancer cells?

a)

They undergo apoptosis.

b)

They do not respond to growth inhibitors

c)

They respond to growth inhibitors.

17.

Which is a function of cyclins?

a)

Cyclins are carbohydrates that regulate DNA replication during the mitosis phase of the cell cycle.

b)

Cyclins are glycoproteins that repair DNA in the beginning of cell cycle.

c)

Cyclins are proteins that regulate when and how often a cell divides.

18.
Which of the following is a type of protein that regulates the cell cycle? 
a)
actin 
b)
myosin 
c)
cyclin 
d)
pepsin 
19.

Cancer promoting substances are called:

a)

Tumors

b)

Carcinogens

c)

Cyclins

d)

Malignant

20.
Which phrase best describes cancer?
a)
absence of cyclins
b)
multiple gene mutations
c)
uncontrolled cell growth
d)
precesnce of genetic defects