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WorksheetsHypertension
Total questions: 15
Worksheet time: 15mins
Which of the following is NOT a stimulus for renin release?
Low sodium in the renal tubular fluid
Increased stretch in the carotid sinus
β1 adrenergic receptor activation
Decreased stretch in the afferent arteriole
Macula densa signaling to the juxtaglomerular cells
Decreased perfusion of the kidneys results in which of the following?
Vasodilation of peripheral vasculature
Decreased sodium reabsorption
Inhibition of the RAAS system
Increased water reabsorption
Parasympathetic stimulation of JG cells
Which of the following is NOT a key factor in the pathogenesis of primary hypertension?
Sodium and water retention
Increased heart rate
Sympathetic nervous system activation
RAAS activation
Hardening of the arteries with age
The lab reports of a 43-year-old female with diabetic nephropathy reveal albuminuria. Which of the following is the primary site of action of the most appropriate drug that would be beneficial in decreasing albuminuria?
Collecting ducts
Right renal artery
Distal convoluted tubule
Afferent arterioles
Efferent arterioles
A 56-year-old male experiences spike in blood pressure due to administration of a vasopressor drug. Which of the following organ responses will be immediately manifested in response to the increased blood pressure?
Miosis
Palpitations
Anuria
Decreased peristalsis
Bradycardia
A 68-year-old man falls down upon getting up from his bed this morning. He also reports feeling of racing heart during the incident. He has a history of essential hypertension and benign hypertrophy of prostate. His blood pressure was inadequately controlled with lisinopril, hydrochlorothiazide and amlodipine. A day before his current visit, his medications were revised. Which of the following medications has most likely caused his current medical situation?
Losartan
Clonidine
Methyldopa
Prazosin
Metoprolol
A 63-year-old female with hypertension has been receiving an antihypertensive for 15 days. Compared to her baseline lab tests before starting the therapy, her lab tests show the following changes today. Which of the following antihypertensive drugs has she been most likely taking?
Hydrochlorothiazide
Lisinopril
Losartan
Clonidine
Nifedipine
A 54-year-old male is started a treatment for hypertension with a medication that produces a decrease in blood pressure by acting on the peripheral adrenergic receptors but does not cause reflex tachycardia. Which of the following drugs is most likely prescribed?
Metoprolol
Labetalol
Diltiazem
Lisinopril
Hydrochlorothiazide
Drug X is given together with a thiazide diuretic for the control of hypertension. The dosage of drug X is increased to maintain control of blood pressure. Which of the following findings would lead you to conclude that the limit of therapeutic effectiveness of the drug X has reached?
Increasing the dose of drug X causes:
Deterioration of hepatic function
An increased incidence and severity of side effects
Prolongation of its half-life
No further decrease in blood pressure
Deterioration of hepatic function and prolongation of half-life
A 60-year-old African-American male with hypertension is started on a treatment with appropriate antihypertensive drugs. After two days he calls the physician office to report palpitations. Which of the following drugs was he most likely prescribed that has caused palpitations?
Captopril
Amlodipine
Metoprolol
Losartan
Diltiazem
The lab results of a 54-year-old male with essential hypertension is prescribed a thiazide medication. His blood tests completed before the prescription show normal serum potassium levels. His physician suggests that regular blood tests will be needed to monitor the serum electrolyte levels subsequent to this therapy. Inhibition of which of the following channels is the primary site of action of the prescribed medication?
Na+/Cl-channels
Na+/Ca+2 channels
Na+/K+ ATPase
Chloride channels
ATP-sensitive K+ channels
Which of the following sets of electrolyte changes in the urine most likely reflects the effects of hydrochlorothiazide?
Na+ Increase; Ca+2 Increase
Na+ Increase; Ca+2 Decrease
Na+ Decrease; Ca+2 Decrease
Na+ Decrease; Ca+2 Increase
The figure below shows the blood pressure recording of a 34-year-old male using an invasive blood pressure measurement technique. Which of the following answer choices represent his pulse pressure?
104 mmHg
98 mmHg
86 mmHg
67 mmHg
36 mmHg
Excess aldosterone secretion would tend to ________ plasma K+ concentration, ________ plasma pH, _______ renin secretion, and ________ blood pressure.
Decrease, decrease, decrease, decrease
Decrease, increase, decrease, increase
Decrease, decrease, decrease, increase
Decrease, increase, increase, increase
A chronic decrease in which of the following would most likely result in chronic hypertension?
Aldosterone
Endothelin
Angiotensin II
Nitric oxide
Vasopressin
