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Worksheets

Hypertension

Total questions: 15

Worksheet time: 15mins

Name
Class
Date
1.

Which of the following is NOT a stimulus for renin release?

a)

Low sodium in the renal tubular fluid

b)

Increased stretch in the carotid sinus

c)

β1 adrenergic receptor activation

d)

Decreased stretch in the afferent arteriole

e)

Macula densa signaling to the juxtaglomerular cells

2.

Decreased perfusion of the kidneys results in which of the following?

a)

Vasodilation of peripheral vasculature

b)

Decreased sodium reabsorption

c)

Inhibition of the RAAS system

d)

Increased water reabsorption

e)

Parasympathetic stimulation of JG cells

3.

Which of the following is NOT a key factor in the pathogenesis of primary hypertension?

a)

Sodium and water retention

b)

Increased heart rate

c)

Sympathetic nervous system activation

d)

RAAS activation

e)

Hardening of the arteries with age

4.

The lab reports of a 43-year-old female with diabetic nephropathy reveal albuminuria. Which of the following is the primary site of action of the most appropriate drug that would be beneficial in decreasing albuminuria?

a)

Collecting ducts

b)

Right renal artery

c)

Distal convoluted tubule

d)

Afferent arterioles

e)

Efferent arterioles

5.

A 56-year-old male experiences spike in blood pressure due to administration of a vasopressor drug. Which of the following organ responses will be immediately manifested in response to the increased blood pressure?

a)

Miosis

b)

Palpitations

c)

Anuria

d)

Decreased peristalsis

e)

Bradycardia

6.

A 68-year-old man falls down upon getting up from his bed this morning. He also reports feeling of racing heart during the incident. He has a history of essential hypertension and benign hypertrophy of prostate. His blood pressure was inadequately controlled with lisinopril, hydrochlorothiazide and amlodipine. A day before his current visit, his medications were revised. Which of the following medications has most likely caused his current medical situation?

a)

Losartan

b)

Clonidine

c)

Methyldopa

d)

Prazosin

e)

Metoprolol

7.

A 63-year-old female with hypertension has been receiving an antihypertensive for 15 days. Compared to her baseline lab tests before starting the therapy, her lab tests show the following changes today. Which of the following antihypertensive drugs has she been most likely taking?

a)

Hydrochlorothiazide

b)

Lisinopril

c)

Losartan

d)

Clonidine

e)

Nifedipine

8.

A 54-year-old male is started a treatment for hypertension with a medication that produces a decrease in blood pressure by acting on the peripheral adrenergic receptors but does not cause reflex tachycardia. Which of the following drugs is most likely prescribed?

a)

Metoprolol

b)

Labetalol

c)

Diltiazem

d)

Lisinopril

e)

Hydrochlorothiazide

9.

Drug X is given together with a thiazide diuretic for the control of hypertension. The dosage of drug X is increased to maintain control of blood pressure. Which of the following findings would lead you to conclude that the limit of therapeutic effectiveness of the drug X has reached?

Increasing the dose of drug X causes:

a)

Deterioration of hepatic function

b)

An increased incidence and severity of side effects

c)

Prolongation of its half-life

d)

No further decrease in blood pressure

e)

Deterioration of hepatic function and prolongation of half-life

10.

A 60-year-old African-American male with hypertension is started on a treatment with appropriate antihypertensive drugs. After two days he calls the physician office to report palpitations. Which of the following drugs was he most likely prescribed that has caused palpitations?

a)

Captopril

b)

Amlodipine

c)

Metoprolol

d)

Losartan

e)

Diltiazem

11.

The lab results of a 54-year-old male with essential hypertension is prescribed a thiazide medication. His blood tests completed before the prescription show normal serum potassium levels. His physician suggests that regular blood tests will be needed to monitor the serum electrolyte levels subsequent to this therapy. Inhibition of which of the following channels is the primary site of action of the prescribed medication?

a)

Na+/Cl-channels

b)

Na+/Ca+2 channels

c)

Na+/K+ ATPase

d)

Chloride channels

e)

ATP-sensitive K+ channels

12.

Which of the following sets of electrolyte changes in the urine most likely reflects the effects of hydrochlorothiazide?

a)

Na+ Increase; Ca+2 Increase

b)

Na+ Increase; Ca+2 Decrease

c)

Na+ Decrease; Ca+2 Decrease

d)

Na+ Decrease; Ca+2 Increase

13.

The figure below shows the blood pressure recording of a 34-year-old male using an invasive blood pressure measurement technique. Which of the following answer choices represent his pulse pressure?

a)

104 mmHg

b)

98 mmHg

c)

86 mmHg

d)

67 mmHg

e)

36 mmHg

14.

Excess aldosterone secretion would tend to ________ plasma K+ concentration, ________ plasma pH, _______ renin secretion, and ________ blood pressure.

a)

Decrease, decrease, decrease, decrease

b)

Decrease, increase, decrease, increase

c)

Decrease, decrease, decrease, increase

d)

Decrease, increase, increase, increase

15.

A chronic decrease in which of the following would most likely result in chronic hypertension?

a)

Aldosterone

b)

Endothelin

c)

Angiotensin II

d)

Nitric oxide

e)

Vasopressin