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Unit 1 AP Biology

Total questions: 50

Worksheet time: 27mins

Name
Class
Date
1.
Organic chemistry is a science based on the study of
a)
functional groups.
b)
vital forces interacting with matter.
c)
carbon compounds.
d)
inorganic compounds.
2.
Which of the following best summarizes the relationship between dehydration reactions and hydrolysis?
a)
Hydrolysis only occurs in the urinary system, and dehydration reactions only occur in the digestive tract.
b)
Hydrolysis creates monomers, and dehydration reactions break down polymers.
c)
Dehydration reactions can occur only after hydrolysis.
d)
Dehydration reactions assemble polymers, and hydrolysis breaks down polymers.
3.
What is the molecule illustrated in the figure below?
a)
a trans polyunsaturated triacylglyceride
b)
a steroid similar to cholesterol
c)
a saturated fatty acid
d)
an unsaturated fatty acid
4.
This is a picture of a?
a)
Amino Acid
b)
Nucleic Acid
c)
Lipid
d)
Polysaccharide
5.
What is this molecule? (hint: Count the C:H:O)
a)
disaccharide
b)
monosaccharide
c)
polysaccharide
d)
starch
6.
What macromolecule makes up the cell membrane's lining?
a)
Saturated Fatty acid chains
b)
Phospholipids
c)
Polypeptide chains
d)
Cellulose polysaccharide Chains
7.
 What molecule is this?
a)
steroid
b)
polysaccharide
c)
phospholipid
d)
triglyceride
8.
How does your body use lipids?
a)
Primary source of energy
b)
energy storage and insulation
c)
speeds up chemical reaction
d)
defense
9.
Which of the 4 major macromolecules provides a quick burst of energy?
a)
Carbohydrates
b)
Lipids
c)
Proteins
d)
Nucleic Acids
10.
Alpha helix and beta pleated sheets are part of what level of protein structure?
a)
primary
b)
secondary
c)
tertiary
d)
quaternary
11.
The fact that ice floats on liquid water is due to the fact that water's solid is ___________ than it's liquid form
a)
less polar
b)
more polar
c)
less dense
d)
more dense
12.
The property of water that allows water molecules to stick to each other is
a)
adhesion
b)
cohesion
c)
density
d)
specific heat
13.
Which biomolecule is mainly hydrocarbons and therefore very hydrophobic?
a)
carbohydrate
b)
nucleic acid
c)
protein
d)
lipid
14.
What molecule is this?
a)
this is a monosaccharide
b)
this is a polysaccharide
c)
this is a protein
d)
this is a lipid
15.
Which fatty acid tail is unsaturated?
a)
Only the bottom tail is unsaturated.
b)
Only the top tail is unsaturated.
c)
Both tails are unsaturated.
d)
Neither tail is unsaturated.
16.

Which of the following best describes water's ability to dissolve certain substances such as glucose, but remain separate from other substances such as oils?

a)

Water molecules are polar, consisting of two partially positive hydrogen atoms, and one partially negative oxygen atom.

b)

Water molecules can only form ionic bonds with polar molecules, such as glucose.

c)

Due to hydrogen bonding, water is more dense as a liquid than a solid.

d)

Water has an overall negative charge, which allows it to easily dissolve nonpolar substances like glucose.

17.

Which of the following examples explains how biological activity relies on water's adhesive properties?

a)

Water travels through vascular tissue (xylem) from the roots to the leaves of a plant.

b)

Stomata (openings) in leaves control transpiration of water out of the leaf as water vapor.

c)

Vacuoles in plant cells swell as water dilutes the contents of the vacuole.

d)

Feathers retain an oily coating that repels water droplets.

18.

Given the structure of water (H2O), which of the following must be true?

a)

Each water molecule can form four hydrogen bonds.

b)

Each water molecule will form covalent bonds with its neighbors.

c)

Water has an overall negative charge.

d)

Water is able to easily dissolve nonpolar substances.

19.

Which of the following describes a covalent bond?

a)

It involves an atom that gains an electron.

b)

Two or more atoms share electron pairs.

c)

Molecules linked by covalent bonds are less dense when in solid form than when in liquid form.

d)

A hydrogen atom with a partial positive charge is attracted to another atom with a partial negative charge.

20.

Which of the following statements regarding carbon is FALSE?

a)

Carbon has the capacity to form single and double bonds.

b)

Carbon has the ability to bond together to form extensive branched or unbranched "carbon skeletons."

c)

Carbon has the ability to bond with up to six other atoms.

d)

Carbon has a tendency to form covalent bonds.

21.

Which of the following best describes the role that water plays in the reaction depicted here?

a)

Water catalyzes the formation of a covalent bond in the dimer through hydrolysis.

b)

When water condenses out of the reaction, a dimer is created as a covalent bond forms between two monomers.

c)

When water combines with the two monomers, a dimer forms.

d)

Water is an input of the reaction, leading to the formation of a covalent bond in the dimer product.

22.

Which of the following questions would a researcher most likely ask if they wanted to know whether a hydrolysis reaction or a dehydration synthesis reaction is occurring?

a)

Are the monomers identical to one another?

b)

Is an enzyme involved in the reaction?

c)

Which polymer is involved in the reaction?

d)

Is water a reactant or product of the reaction?

23.

Lactose is a dimer sugar composed of two monomeric subunits (galactose and glucose). In an investigation, researchers placed intestinal cells in a nutrient medium containing lactose. The researchers determined that the lactose had broken down to galactose and glucose in the manner depicted in the reaction shown here.


The cells were then modified and re-exposed to the lactose medium. The researchers were no longer able to detect the presence of galactose and glucose. Which of the following conclusions best explains an outcome of this modification?

a)

The cells were unable to hydrolyze lactose, resulting in the formation of a covalent bond between galactose and glucose.

b)

The cells were unable to hydrolyze the lactose dimer into its monomeric subunits.

c)

The cells were able to perform dehydration synthesis reactions in order to break down lactose into its monomeric subunits.

d)

The cells were able to undergo a reverse reaction and build lactose.

24.

A researcher wants to identify a newly isolated DNA strand. The first step in identifying the DNA strand is to measure its length. To do this, the researcher wants to develop a fluorescent tag that emits light once it binds to both ends of the strand.

Which of the following best describes how the researcher should develop a fluorescent tag with an ability to bind to both ends of the strand?

a)

The tag should have an affinity to bind only guanine (G) and cytosine (C) nitrogenous bases.

b)

The tag should have an affinity to bind only free amino (-NH2) and carboxyl (-COOH) functional groups.

c)

The tag should have an affinity to bind only adenine (A) and thymine (T) nitrogenous bases.

d)

The tag should have an affinity to bind only free 3' hydroxyl (-OH) and 5' phosphate (-PO4) functional groups.

25.

The image depicts how the bacterial protein barnase undergoes modifications that involve changing its conformation, or shape. In order to function in the cell, barnase has to be folded from a nonfunctional conformation into a functional conformation.

a)

The functional conformation of barnase has a tertiary structure because it consists of a polypeptide chain folded into a three-dimensional shape.

b)

The functional composition of barnase has a quaternary structure because it consists of interactions between multiple polypeptide units.

c)

The functional composition of barnase has a secondary structure because it consists of a single alpha-helix.

d)

The functional composition of barnase has a primary structure because it consists of a linear chain of amino acids.

26.

Amino acids can be distinguished from one another by

a)

the number of R groups found on the amino acid molecules.

b)

the type of bond between the R group and the rest of the amino acid molecule.

c)

the chemical properties of their R groups.

d)

the chemical properties of their amino and carboxyl groups.

27.

Which of the following statements about enzymes is false?

a)

They are monomers used to build proteins.

b)

They regulate virtually all chemical reactions in a cell.

c)

They function as chemical catalysts.

d)

They increase the rate of chemical reactions.

28.

Your first big biology exam is coming up in a few days, and in order to prepare for late-night study sessions, you buy a box of Yummies, a delicious type of snack cake. After checking out the nutrition facts label on the side of the box, you discover that a single Yummie cake contains 4.5 grams of total fat, 27 grams of carbohydrate, 0 grams of fiber, and 1 gram of protein.


The pH of the stomach is extremely acidic (~ pH 2). If you ate a Yummie cake, what do you think would happen to the protein that you ingested as it passes through the stomach?

a)

The protein would form longer proteins via dehydration reactions.

b)

The protein would get broken down via dehydration reactions.

c)

The protein would become denatured due to the acidic environment.

d)

The protein would speed up digestion because it is an enzyme.

29.

What is the complementary sequence to the DNA strand TCGATGG?

a)

AGCUACC

b)

AGCTACC

c)

GGTAGCT

d)

TCGATGG

30.

Which of the following correctly matches the macromolecule with its monomer?

a)

carbohydrates: monosaccharides

b)

proteins: polysaccharides

c)

lipids: nucleotides

d)

nucleic acids: polypeptides

31.

In the early 1950’s, a team of researchers led by Erwin Chargaff conducted a series of experiments related to deciphering the chemical composition of DNA. In one experiment, Chargaff’s team examined samples of DNA from different species of sea urchins. The results of this experiment are summarized in the table pictured. Which of the following results from the experiment is most consistent with the base-pairing rules of DNA?

a)

The average molar ratio of guanine to cytosine is less than the average molar ratio of adenine to guanine across all species in the experiment.

b)

The percentage of adenine nucleotides is roughly equal to the percentage of thymine nucleotides across all species in the experiment.

c)

The average molar ratio of adenine to guanine is greater than the average molar ratio of thymine to cytosine across all species in the experiment.

d)

The percentage of thymine nucleotides is roughly equal to the percentage of cytosine nucleotides across all species in the experiment.

32.

In the cell membrane, carbohydrate chains can be covalently linked to membrane proteins to form glycoproteins. They can also be covalently linked to membrane phospholipids to form glycolipids. These two cell membrane structures are shown in the image provided.


During an investigation, researchers discover a new toxin that enters a cell after binding to a carbohydrate on the cell membrane. Which of the following best describes how the toxin attaches to the cell membrane?

a)

The toxin attaches to specific phospholipids on the cell membrane.

b)

The toxin attaches to specific amino acids on the cell membrane.

c)

The toxin attaches to specific fatty acids on the cell membrane.

d)

The toxin attaches to specific monosaccharides on the cell membrane.

33.

Cowpox is classified as a DNA virus because its genome, or genetic material, consists of double-stranded DNA.

Which of the following claims is best supported by the information above?

a)

Cowpox contains a five-carbon sugar called ribose in its nucleic acid structure.

b)

Uracil nucleotides are not found in the cowpox genome.

c)

Cowpox has a single-stranded nucleic acid structure.

d)

Thymine nucleotides are not found in the cowpox genome.

34.

The following excerpt describes a potential origin of the first living cells on earth:


"We have proposed that a simple primitive cell, or protocell, would consist of two key components: a protocell membrane that defines a spatially localized compartment, and an informational polymer that allows for the replication and inheritance of functional information."


Based on this excerpt, which of the following questions would best direct an investigation on whether the "informational polymer" is DNA or RNA?

a)

Which type of bonds connect individual nucleotides in the sugar-phosphate backbone of the informational polymer?

b)

Which nitrogenous bases are present in the structure of the informational polymer?

c)

Which functional group is located on the 3' end of the informational polymer?

d)

Which functional group is located on the 5' end of the informational polymer?

35.

Which of the following molecules is a carbohydrate?

a)

C51H98O6

b)

C22H49O10N5

c)

C45H84O8P4

d)

C60H100O50

36.
What is the total magnification of a microscope with an eyepiece magnification of 10x and an objective lens magnification of 50x ?
a)
500x
b)
50x
c)
5x
d)
5000x
37.
_________ proteins are integral membrane proteins that form channels across the membrane through which some substances can pass. 
a)
Anchored
b)
Gated
c)
Embeded
d)
Channel 
38.
What do elements with atomic numbers 6, 14,  and 22 have in common?
a)
same number of electrons
b)
same atomic mass
c)
a)same valence and will form the same number of covalent bonds
d)
all of the above   
39.
Water is a polar molecule because of the
presence of ___________ bonds.
a)
ionic
b)
covalent
c)
polar covalent
d)
hydrogen
40.
The four emergent properties of water that are important for life:
a)
cohesion, expansion upon freezing, high heat of evaporation, and capillarity 
b)
cohesion, moderation of temperature, expansion upon freezing, and solvent properties
c)
moderation of temperature, solvent properties, high surface tension, and capillarity
d)
heat of vaporization, high specific heat, high surface tension, and 
41.
Which of the following explains what is happening when sodium is disolved in water
a)
more hydrogen bonds are forming between water molecules 
b)
sodium and chloride atoms are separating from one another
c)
hydration shells are forming around sodium and chloride ions
d)
covalent bonds are breaking and reforming 
42.
A calorie is defined as:
a)
the amount of energy required to raise the temperature of 1 gram of water by 1 degree F
b)
the amount of energy required to raise the temperature of 1 gram of water by 1 degree C
c)
the amount of energy released by metabolism of one gram of glucose
d)
the amount of energy contained in one gram of fat
43.
In humans, blood pH is around 7.4, and a decrease in blood pH to 6.4 would be fatal. A drop by 1 pH unit represents which of these?
a)
1/10 as many hydrogen ions
b)
1/7 as many hydrogen ions
c)
twice as many hydrogen ions in the solution
d)
1/2 as many hydrogen ions in the solution
44.
What functional group is commonly used in cells to transfer energy from one organic molecule to another?
a)
carboxyl 
b)
 sulfhydryl 
c)
hydroxyl 
d)
phosphate
45.
How many isomers can you make from the molecular formula C6H12O6?
a)
1
b)
2
c)
4
d)
more than 6
46.
Why are human enzymes that digest starch unable to digest cellulose?
a)
Cellulose is made of amino-containing sugars that cannot be metabolized.
b)
Cellulose contains L-glucose instead of D-glucose; starch-digesting enzymes are specific for polymers of D-glucose.
c)
Cellulose has beta-glycosidic linkages; starch-digesting enzymes cleave only alpha-glycosidic linkages.
d)
Cellulose has beta-galactoside linkages that only bacterial beta-galactosidases can cleave.
47.
Which type of biological polymer has the least diversity in physicochemical properties and structure?
a)
polysaccharides
b)
polypeptides 
c)
DNA
d)
RNA
48.
Compared to tropical fish, arctic fish oils have
a)
more unsaturated fatty acids.
b)
more cholesterol.
c)
fewer unsaturated fatty acids.
d)
more trans-unsaturated fatty acids.
49.
Sickle-cell disease is caused by a mutation in the beta-hemoglobin gene that changes a charged amino acid, glutamic acid, to valine, a hydrophobic amino acid. Where in the protein would you expect to find glutamic acid?
a)
on the exterior surface of the protein
b)
in the interior of the protein, away from water
c)
at the active site, binding oxygen
d)
at the heme-binding site
50.
Ceviche is prepared by marinating fresh raw fish in citrus juice for several hours, until the flesh becomes opaque and firm, as if cooked. How does citrus juice render the seafood safe to eat?
a)
Acidic pH denatures (unfolds and inactivates) proteins by disrupting their hydrogen bonds.
b)
Citrus juice denatures proteins by disrupting their ionic bonds.
c)
Citrus juice contains enzymes that hydrolyze peptide bonds to break apart proteins.
d)
Citrus juice dissolves cell membranes by disrupting hydrophobic interactions.