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IBD

Total questions: 8

Worksheet time: 5mins

Name
Class
Date
1.

How should oral prednisolone therapy be withdrawn in patients being treated for ulcerative colitis or Crohn’s disease?

a)

Between 6-8 weeks

b)

Between 1-3 weeks

c)

Between 9-10 weeks

d)

Between 11-12 weeks

e)

Between 4-5 weeks

2.

When azathioprine is co-prescribed with allopurinol, by how much should the dose of azathioprine be reduced?

a)

Reduce by 75%

b)

Reduce by 10%

c)

Reduce by 25%

d)

Reduce by 15%

e)

Reduce by 20%

3.

Why is it important to maintain patients on the same brand of mesalazine?

What is the most appropriate answer?

a)

The brand indicates the form of medication

b)

Different brands have different release profile of mesalazine

c)

Different brands contain different salts of mesalazine

d)

Different brands have different side effects

e)

Different brands have different bioavailability

4.

Which of the following pre-treatment screening checks are required when a patient is initiated on infliximab?

a)

Tuberculosis

b)

Hepatitis B and C

c)

Varicella zoster

d)

Pneumococcal infection

e)

HIV

5.

Which scoring system is used to assess symptom severity in ulcerative colitis?

a)

Child-Pugh Score

b)

Wells Score

c)

Crohn’s Disease Activity Index

d)

Harvey-Bradshaw Index

e)

Truelove and Witt’s Index

6.

A 56 year old male patient weighing 65kg has been admitted to hospital with a flare-up of ulcerative colitis. He has blood in this stools and has more than 6 bowel movements per day. The doctor wants to prescribe VTE prophylaxis for this patient.


What is the most appropriate answer?


eGFR>90

Platelets 258 x109/L (150-450 x109/L)

a)

Hold enoxaprin until flare-up has resolved

b)

Give enoxaparin 40mg ONCE daily

c)

Give enoxaparin 100mg ONCE daily

d)

Hold enoxaparin for 3 days then give enoxaparin 20mg ONCE daily

e)

Give aspirin 75mg ONCE daily

7.

When should azathioprine or mercaptopurine be stopped and experts advice obtained?

a)

WBC <4x109L-1

b)

Neutrophils <2x109L-1

c)

Platelets <150x109L-1

d)

AST >3xULN

e)

ALT >3xULN

8.

A 31 year old male patient has been newly started on azathioprine for ulcerative colitis. He has been prescribed azathioprine 100mg ONCE daily. The doctor asks you to review this medication.


WBC 9 x109/L (5-10 x109/L)

Platelets 355 x109/L (150-450 x109/L)

ALT 25 IU/L (<50 IU/L)

TPMT 55 mU/L (68-150 mU/L)


What is the most appropriate advise to give to the doctor?

a)

Reduce the daily dose by half

b)

Increase the daily dose by half

c)

Keep the dose the same

d)

Reduced daily dose by 25%

e)

Increase daily dose by 25%