Which of the ff is not a part of the Von Hippel Lindau syndrome?

Philadelphia chromosome is associated with which neoplasm?

A 60 year old female consulted due to right ovarian mass. Biopsy reveals mature bone, cartilage, and skin adnexal structures. However, there were primitive neural, adipose and muscle components. What is the most likely diagnosis?

When hypophosphorylated, this gene product exerts anti-proliferative effects by binding and inhibiting E2F transcription factors that regulate genes required to pass through the G1-S phase cell cycle checkpoint

Which of the breast tumors shows sheets or large masses of atypical glandular cells growing in an anarchic, disorganized fashion?

A 30 year old male presented with a scrotal mass consistent with a dysgerminoma. Microscopic examination reveals primitive tumor cells in the lungs, liver and pleural fluid. Which histologic characteristic of malignancy is present?

Which of the following statements is not true regarding the virus implicated with malignancy?

A 30 year old female consulted an OBGYN for an annual physical examination. Cervical examination shows leuko whitening upon application of acetic acid. Pap smears show atypical squamous cells with cytoplasmic halos. What test may confirm your diagnosis?

WT-1 mutation is linked to:

A 50 year old male with fungating mass of the lower lip. Biopsy reveals atypical cells with high nucleus to cytoplasm ratio, forming sheets and keratin pearls. Which immunostain would be helpful in the diagnosis?

Which of the following statements about neoplasms is false?

In - situ (borderline) epithelial cancers display the cytologic features of malignancy without;

It codes for a variety of growth factors, receptors, and signal relay or transcription factors which act in concert to control entry into the cell cycle.

A two year old male presented with a 2 inch sized pouch like mass 2 feet from the ileocecal valve. It consists of all 3 layers of the bowel wall, with normal gastric and pancreatic tissues. These ectopic tissues are most likely:

A 60 year old female presented with rectal bleeding. A 3 cm polypoid mass was noted on colonoscopy. Biopsy shows loss of uniformity of the glandular cells as well as loss in their architectural orientation. These are consistent with what feature of tumors?

A common carcinogen found in peanuts and grains is:

Oncogenic RNA viruses are able to integrate themselves into the DNA of the host cells via;

Which of the ff tumors would show tumor cells with tadpole shaped cells with large, lobate, hyperchromatic nuclei and multipolar mitotic figures?

Which of the ff is not part of Multiple Endocrine Neoplasia-1?

Which of the ff viruses is closely linked to the developmental of nasopharyngeal carcinoma and burkitt’s lymphoma?

This cyclin dependent kinase forms complex with cyclin E in late G1, which is involved in G1/S transition.

This gene is responsible for renal cell carcinoma development

Which checkpoint component is activated by mechanisms that sense double stranded DNA breaks?

A high level of chromosomal material accumulation and mitosis, implies a faster growing malignancy, reflected histologically by: