NEW
Font size
WorksheetsPathophysiology Exam 1 Given Q's T/F (Blood)
Total questions: 57
Worksheet time: 29mins
Mobilization defines the movement of the HSC from the bone marrow to the peripheral blood.
T
F
Lymphopoiesis and Myelopoiesis are controlled by stem cell factors.
T
F
Monocytes are modified lymphocytes
T
F
Erythropoiesis is stimulated by TPO, which is produced by the liver cells.
T
F
Basophils are derived from myeloid progeny.
T
F
Megakaryocytes are mainly found in the peripheral blood.
T
F
In Polycythemia Vera, there is excessive erythropoietin secretion by the kidneys.
T
F
A regular blood film is usually dominated by neutrophils.
T
F
Neutrophils and platelets outnumber RBCs in 1 microliter of blood.
T
F
Hematocrit is a value that describes the mean average size of RBCs.
T
F
The periphery of RBCs is paler than the center.
T
F
Neutrophils have a shorter lifespan than platelets.
T
F
Neutrophils have a shorter lifespan than RBCs.
T
F
Multilobed nucleus is a character of B-lymphocytes.
T
F
Basophils are filled with acidic granules.
T
F
Eosinophils are filled with acidic granules.
T
F
Bands are immature neutrophils that increase in number during infection.
T
F
Lymphocytes are characterized by acidophilic granules.
T
F
IgG is produced by T lymphocytes.
T
F
Platelets are cell fragments free from phospholipids and nucleus.
T
F
Platelet activation is also known as platelet aggregation.
T
F
Binding of thromboxane A2 to platelets promote platelet degranulation.
T
F
Thrombin is a serine protease made by endothelial cells.
T
F
Von Willebrand Factor binds to and act as a carrier for factor XIII.
T
F
Primary hemostasis is characterized by the conversion of fibrinogen into fibrin.
T
F
Primary homeostasis is characterized by an increase in extracellular calcium.
T
F
The amplification step in secondary hemostasis occurs at the surface of the injured cells.
T
F
Factor VIII is activated by the release of the Von Willebrand factor.
T
F
The amplification step in the secondary hemostasis involves the formation of the Tenase and Prothrombinase complexes.
T
F
Plasmin is the main catalytic enzyme during the initiation phase of hemostasis.
T
F
Alpha-2 antiplasmin promotes thrombus formation.
T
F
PAI promotes thrombus formation.
T
F
t-PA promotes thrombus formation.
T
F
Plasmin degrades fibrin polymers.
T
F
Platelet disorders are mainly because liver produces less amount of TPO.
T
F
Increase in spleen size activity induce thrombocytopenia.
T
F
Hemophilia B is a genetic disorder caused by factor VIII deficiency.
T
F
Hemophilia B is a genetic autosomal disorder caused by factor IX deficiency.
T
F
Pica is a characteristic for megaloblastic anemia.
T
F
Hepcidin production increases with the increase in iron intracellular stores.
T
F
Hepcidin increases the stability of Ferroportin.
T
F
One Heme molecule contains four globing subunits.
T
F
One Heme molecule contains four iron atoms.
T
F
In IDA, you should expect hypoxia and increased plasma erythropoietin.
T
F
IDA could lead to glossitis and gastric atrophy.
T
F
IDA usually affects the nervous system and induces nerve damage.
T
F
IDA is an autoimmune disease.
T
F
Pernicious anemia is an autoimmune disease.
T
F
Vitamin B12 deficiency leads to microcytic anemia.
T
F
Antibodies against the gastric intrinsic factor leads to neutropenia.
T
F
Absolute neutropenia is a rare disease, while cyclic neutropenia is a more common disease.
T
F
Neutrophil elastase mutation may lead to absolute neutropenia.
T
F
Neutrophil elastase mutation could result in cyclic increase in monocyte count.
T
F
Neutrophil elastase inhibits the differentiation of myeloblasts into neutrophils.
T
F
Type I HIT is associated with antibody formation.
T
F
Type II HIT is an immune based reaction that leads to thrombocytopenia and thrombosis.
T
F
Both type I and II HIT are initiated by heparin binding to PF4.
T
F
