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Genetic Engineering

Total questions: 25

Worksheet time: 13mins

Name
Class
Date
1.

DNA strands can be clipped crosswise at selected positions by using enzymes called

a)

palindromes

b)

DNA polymerases

c)

restriction endonucleases

d)

ligases

2.

Which technique will hopefully be used to identify and devise treatments for diseases based on the genetic profile of the disease?

a)

genetic engineering

b)

PCR

c)

antisense technology

d)

microarray analysis

3.

The polymerase chain reaction (PCR) has been used in all of the following fields, except

a)

gene mapping

b)

forensics

c)

medicine

d)

none of the choices; it is used for all these fields

4.

Which PCR step causes the denaturation of double-stranded DNA?

a)

Repeat the cycle of heating and cooling

b)

Add primers

c)

Heat target DNA to 94 degrees Celsius

d)

Cool DNA to between 50 degrees and 65 degrees Celsius

5.

The use of an organism's biochemical processes to create a product is

a)

Bioremediation

b)

gene probes

c)

biotechnology

d)

recombinant DNA

6.

Transgenic animals

a)

will pass genes on to their offspring

b)

commonly include mice

c)

can be engineered to become factories for manufacturing proteins

d)

All of these choices are correct

7.

Recombinant strains of this organism are released to colonize plant roots to produce an insecticide to destroy invading insects.

a)

Pseudomonas fluorescens

b)

Thermus aquaticus

c)

Escherichia coli

d)

Saccharmonyces cerevisiae

8.

All of the following are correct about DNA fingerprinting, except

a)

it cannot be used on specimens older than five years

b)

it can be used to analyze evidence when only minute amounts of DNA are found

c)

it is routine to use it as trial evidence in the U.S.

d)

it displays the unique pattern of an individual's DNA fragments

9.

Which of the following drugs is/are produced by genetic engineering and approved for human use?

a)

tissue plasminogen activator

b)

Factor VIII

c)

Human growth hormone

d)

All of these choices are correct

10.

Amplification of DNA is accomplished by

a)

Southern blot

b)

polymerase chain reaction

c)

gene probes

d)

All of these choices are correct

11.

Restriction endonucleases are obtained from various species of bacteria.

a)

True

b)

False

12.

Collections of isolated genes maintained in a cloning host is known as

a)

transgenic organisms

b)

Genomic libraries

c)

cloning vectors

d)

CRISPR

13.

The deliberate removal of genetic material from one organism and combining it with a genetic material of another organism is a specific technique called

a)

genetic engineering

b)

gel electrophoresis

c)

recombinant DNA technology

d)

gene probes

14.

Which of the following regions of DNA would be of most value for forensic analysis?

a)

DNA sequences that are typically identical for all humans

b)

Most DNA sequences are equally valuable for forensic analysis

c)

DNA sequences that differ among humans, with a maximum of two different alleles

d)

SNa sequences that are quite variable with multiple different alleles

15.

Sequencing a gene automatically identifies which gene it is.

a)

True

b)

False

16.

All of the following are desirable features in a microbial cloning host, except

a)

the host has a slow growth rate

b)

the host will secrete a high yield of proteins from expressed foreign genes

c)

the host can be grown in large quantities

d)

the host is capable of accepting plasmid vectors

17.

The Western Blot technique detects

a)

recombinant DNA

b)

specific genetic marker sequence on genes

c)

DNA

d)

proteins

18.

Which of the following methods determines which genes are actively transcribed in a cell under a variety of conditions?

a)

antisense therapy

b)

DNA fingerprinting

c)

microarray analysis

d)

gene mapping

19.

Reverse transcriptase is used to make cDNA from an RNA template.

a)

True

b)

False

20.

An example of gene therapy is the insertion of the gene for human growth hormone in E. coli cells.

a)

True

b)

False

21.

When patient tissues are transfected with viruses carrying a needed, normal human gene, the technique is called

a)

gene therapy

b)

DNA fingerprinting

c)

cloning

d)

antisense therapeutic

22.

Geneticists can make complimentary DNA copies of messenger, transfer, and ribosomal RNA by using

a)

palindromes

b)

reverse transcriptases

c)

ligases

d)

restriction endonucleases

23.

A technique that separates a readable pattern of DNA fragments is

a)

gene probes

b)

gel electrophoresis

c)

biotechnology

d)

recombinant DNA

24.

When DNA is heated, the two strands will separate.

a)

True

b)

False

25.

Which of the following would be of LEAST value in DNA profiling?

a)

STR short tandem repeat) analysis

b)

sequencing blood group alleles

c)

analysis of SNPs (single nucleotide polymorphisms)

d)

mitotyping