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AP Bio Advanced Genetics

Total questions: 17

Worksheet time: 16mins

Name
Class
Date
1.
Which of the following statements best describes what a Barr body is and its significance?
a)
it is an inactivated Y chromosome and results in a man being sterile
b)
It is an inactivated Y chromosome, and the person who has it appears female
c)
It is an inactivated X chromosome and results in females with half their cells have one X inactivated and in the other half of their cells have the other X inactivated
d)
it is an inactivated X chromosome and results in females who are sterile
2.

Which of the following is an example of polygenic inheritance?

a)

pink flowers in snapdragons

b)

The ABO Blood group in humans

c)

Skin color in humans

d)

Huntington's disease in humans

3.

Suppose the cross-over percentages for three gene pairs are: A to B = 9.5%, B to C = 14.5%, and A to C = 5%. Which of the following sequences could represent the order of these genes on a chromosome?

a)

CAB

b)

ABC

c)

CBA

d)

ACB

4.

If you cross AaBbCc x AABbcc, what's the chance of getting an AABBcc offspring?

a)

12.5%

b)

50%

c)

6.25%

d)

3.13%

5.
Australian Shepherds are a breed of dogs whose coat color is directly impacted by two different genes. The gene that determines basic coat color exhibits a dominant allele (B) for black coat color and a recessive allele (b) for red coat color. Additionally, these dogs can have a solid coat color (mm) or a mixed pattern coat color called merle (Mm). The homozygous dominant coat color is called a lethal white (MM) which produces pups that are deaf and blind. What is the probability that two red Australian shepherds will produce a black pup?
a)
0
b)
1/4
c)
1/2
d)
3/4
6.
In horses, the grey coat color (G) is dominant to non-grey coat color (g). Additionally, some horses have a genetic disorder called hyperkalemic periodic paralysis or HYPP. HYPP is an inherited autosomal dominant disorder that affects the sodium channels in muscle cells. HYPP (H) is dominant to the normal condition (h). If a non-grey, normal stallion sires a foal that is not grey and does not have HYPP, which of the following genotypes are possible genotypes for the mother?
a)
GGhh and ggHH
b)
ggHH and GgHh
c)
GGHH and GGHh
d)
GgHh and gghh
7.

process by which information encoded in a gene is used to synthesize a functional gene product, such as a protein, which results in the phenotypic manifestation of the gene.

a)

gene expression

b)

genetics

c)

genotype

d)

phenotype

8.
If a father is AA and a mother is AB, what is the probability for a child with AB blood? 
a)
0%
b)
25%
c)
50%
d)
75%
9.

The genotype of the affected son and daughter at the bottom of this pedigree must be...

a)

AA

b)

aa

c)

Aa

d)

XaY and XaXa

10.
Which of the following statements is true regarding blood types?
a)
A and O are codominant, B is recessive.
b)
B and O are codominant, A is recessive.
c)
A and B are codominant, O is recessive.
d)
A , B and O are all codominant with each other.
11.
Suppose a male dog has the genotype BBgg, which of the following is true regarding the alleles found in his sperm?
a)
They all carry BG
b)
Some carry B's, some carry g's
c)
Some carry b's, some carry G's
d)
They all carry Bg
12.

What is the mode of inheritance shown here?

a)

Sex Linked Recessive

b)

Autosomal Dominant

c)

Autosomal Recessive

d)

Mitochondrial

e)

Maternal Imprinting

13.

What is the mode of inheritance shown here?

a)

Autosomal Recessive

b)

Autosomal Dominant

c)

Sex Linked Recessive

d)

Mitochondrial

e)

paternal imprinting

14.
What is the relationship between person I-1 and III-2?
a)
Father and Son
b)
Father and Daughter
c)
Grandfather and Granddaughter
d)
Uncle and Niece 
15.

Based on this pedigree, individual II - 1 must be genotype...

a)

AA

b)

Aa

c)

aa

d)

XAY

e)

none of the above since this is a gene carried in mtDNA

16.

Labradors can be either B = Black or b = Chocolate. Another gene, E, causes the labs to be unable to express either pigment in the homozygous recessive state (ee) and the labs appear yellow.


A dog that is BbEe is crossed with another of genotype bbEe. What is chance of having yellow offspring?

a)

0%

b)

50%

c)

25%

d)

75%

e)

12.5%

17.

At which stage in the lives of identical twins is the DNA code expected to be most similar?

a)

Age 6 months

b)

Age 21

c)

Age 55

d)

any age; the DNA code does not change during an individual's lifetime (just the expression of DNA).

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