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BB MODULE 5 ASSESSMENT

Total questions: 26

Worksheet time: 11mins

Name
Class
Date
1.

The ABO gene is located on the locus of ____________.

a)

Chromosome 12

b)

Chromosome 9

c)

Chromosome 6

d)

Chromosome 3

2.

The immunodominant sugar on Blood group B patient is?

a)

L-fucose

b)

D-galactose

c)

N-acetyl-D-galactosamine

d)

Galactose

3.

The enzyme produce by H gene is called?

a)

galactosyl transferase

b)

N acetyl-L-galactosaminyl transferase

c)

D- galactosyl transferase

d)

L- fucosyl transferase

4.

The D- galactosyl transferase is the enzyme that adds the immunodominant sugar D-galactose for the formation of?

a)

H antigen

b)

O antigen

c)

A antigen

d)

B antigen

5.

The donor nucleotide involve in the formation of A antigen is?

a)

UDP-GAL

b)

GDP-FUC

c)

UDP-GALNAC

d)

GALNAC

6.

Precursors substances (PS) are comprised of identical sugars which includes the following except?

a)

galactose

b)

N- acetyl glucosamine

c)

glucose

d)

Fucose

7.

This gene/allele codes for a fucosyl transferase enzyme that adds fucose onto Type 1 chains in secretory glands.

a)

H gene

b)

A gene

c)

B gene

d)

Se gene

8.

Which of the following is an amorph allele?

a)

B allele

b)

A allele

c)

O allele

d)

H allele

9.

What antibody does a type A person naturally make

a)

Anti-A

b)

Anti-B

c)

Anti-AB

d)

Anti-H

10.

What is forward typing?

a)

Testing patient red cells for antigen

b)

Testing known reagent red cell

c)

Testing patient serum for antibodies

d)

Testing known antibodies

11.

What is backward or reverse typing?

a)

Testing patient red cells for antigen

b)

Testing known reagent red cell

c)

Testing patient serum for antibodies

d)

Testing known antibodies

12.

Anti-B is found in which patients (select all that apply).

a)

Type O

b)

Type B

c)

Type A

d)

Type AB

13.

What is reverse typing?

a)

Patient cells + known antibodies

b)

Patient cells + donor serum

c)

Patient serum + donor cells

d)

Patient serum + known red cells

14.

Jim has type AB blood. His dad could be type O.

a)

TRUE

b)

FALSE

15.

Jim has type AB blood. His dad could be type O.

a)

TRUE

b)

FALSE

16.

If one of your parents is blood type A and the other is type B, which of the following blood types could you be?

a)

O

b)

A or B

c)

AB

d)

Any of these

e)

None of these

17.

The presence or absence of the ABH antigens on the red blood cell membrane is controlled by the?

a)

B gene

b)

A gene

c)

H gene

d)

O gene

e)

Se gene

18.

It serves as the foundation upon which A and B antigens are built.

a)

ABO gene

b)

Se gene

c)

H antigen

d)

HH genotype

19.

ABH Ags on RBCs are derived from?

a)

Type II chains

b)

Type I Chains

20.

All of the following are characteristics of Bombay individuals except?

a)

Presence of Anti-A, Anti-B and a potent Anti-H

b)

Absence of L-fucosyltransferase in serum and H antigens in the red cells

c)

A, B, H Nonsecretor

d)

Strong reactivity with anti-I

e)

Absence of A or B enzymes in the serum

21.

This type of Bombay phenotype demonstrate A or B enzymes on serum but NO H enzyme

a)

Classical Bombay Phenotype

b)

Category I

c)

Category II

d)

Category III

e)

Parabombay

22.

This is demonstrated by present of trace amounts of A antigen on B RBCs due to synthesis of A antigen by the B-gene enzyme

a)

Acquired B phenotype

b)

B[A] phenotype

c)

Cis-AB phenotype

d)

Parabombay phenotype

23.

Which of the following would react with Dolichos biflorus reagent?

a)

A1

b)

A2

c)

B antigen

d)

H antigen

24.

Which of the following has the least amount of H antigen?

a)

A2B

b)

B

c)

A2

d)

A1

e)

A1B

25.

Possible Genotypes of a Group A secretor?

a)

OO; HH/Hh; Sese/Sese

b)

BB/BO; HH/Hh; SeSe/Sese

c)

AB; HH/Hh; SeSe/Sese

d)

AA/AO; HH/Hh; SeSe/Sese

26.

Which of the following blood type has antibodies that is IgG in nature?

a)

A

b)

AB

c)

B

d)

O