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Molecular Basis of Inheritance 4

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

DNA replication takes place at _________ phase of the cell

cyle.

a)

G1

b)

S

c)

G2

d)

M

2.

The process of copying genetic information from one strand of DNA to RNA is termed as _________ .

a)

replication

b)

transcription

c)

translation

d)

reverse transcription

3.

The enzyme DNA dependent RNA polymerase catalyses the polymerisation reaction in ___________direction.

a)

only 5’ → 3’

b)

only 3’ → 5’

c)

both (a) and (b)

d)

none of these

4.

If the sequence of bases in coding strand of DNA is ATTCGATG, then the sequence of bases in mRNA will be

a)

TAAGCTAC

b)

UAAGCUAC

c)

ATTCGATG

d)

AUUCGAUG.

5.

If the sequence of bases in DNA is GCTTAGGCAA then the sequence of bases in its transcript will be

a)

GCTTAGGCAA

b)

CGAATCCGTT

c)

CGAAUCCGUU

d)

AACGGAUUCG.

6.

Transcription unit

a)

starts with TATA box

b)

starts with pallendrous regions and ends with rho factor.

c)

starts with promoter region and ends in terminator region

d)

starts with CAAT region.

7.

During transcription, the site of DNA molecule at which RNA polymerase binds is called

a)

promoter

b)

regulator

c)

receptor

d)

enhancer.

8.

Polycistronic messenger RNA (mRNA) usually occurs in

a)

bacteria

b)

prokaryotes

c)

eukaryotes

d)

both (a) and (b)

9.

In transcription in eukaryotes, heterogenous nuclear RNA (hnRNA) is tmascribed by

a)

RNA polymerase I

b)

RNA polymerase II

c)

RNA polymerase III

d)

all of these.

10.

Methyl guanosine triphosphate is added to the 5’ end of hnRNA in a process of

a)

splicing

b)

capping

c)

tailing

d)

none of these

11.

In eukaryotes, the process of processing of primary transcript involves

a)

removal of introns

b)

capping at 5’end

c)

tailing (polyadenlation) at 3’ end

d)

all of these.

12.

In a n/RNA molecule, untranslated regions (UTRs) are present at

a)

5’ – end (before start codon)

b)

3’ – end (after stop codon)

c)

both (a) and (b)

d)

3’- end only.

13.

UTRs are the untranslated regions present on

a)

rRNA

b)

hnRNA

c)

mRNA

d)

/RNA

14.

Which of the following statements is correct regarding ribosomes ?

a)

Most of a cell’s DNA molecule are stored there.

b)

Complete polypeptide is released from there.

c)

mRNAs are produced there.

d)

DNA replication takes place there.

15.

Regulation of gene expression occurs at the level of

a)

transcription

b)

processing/splicing

c)

translation

d)

all of these.

16.

During expression of an operon, RNA polymerase binds to

a)

structural gene

b)

regulator gene

c)

operator

d)

promoter.

17.

The sequence of structural genes in lac operon is

a)

Lac A, Lac Y, Lac Z

b)

Lac A, Lac Z, Lac Y

c)

Lac Y, Lac A, Lac A

d)

Lac Z, Lac Y, Lac A

18.

Which of the following cannot act as inducer ?

a)

Glucose

b)

Lactose

c)

Galactos

d)

Both (a) and (c)

19.

Human genome consists of approximately

a)

3 × 109 bP

b)

6 × 109 bp

c)

20,000 – 25,000 bp

d)

2.2 × 104 bp.

20.

Estimated number of genes in human beings is

a)

3,000

b)

80,000

c)

20,500

d)

3 × 109