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Pedigrees (autosomal and x-linked)

Total questions: 25

Worksheet time: 49mins

Name
Class
Date
1.

What does a shaded circle represent?

a)

unaffected female

b)

affected female

c)

unaffected male

d)

affected male

2.
How many generations are shown in this pedigree?
a)
1
b)
2
c)
3
d)
4
3.

Is this pedigree tracking a disorder that is dominant or recessive?

a)

Dominant

b)

Recessive

4.

If this pedigree shows a recessive disorder, what MUST the genotype of generation II individual 2 be?

(individual 4)

a)

HH

b)

Hh

c)

hh

5.

What is the family relationship between the two affected individuals in this pedigree?

a)

Mother and daughter

b)

Grandmother and granddaughter

c)

Aunt and niece

d)

Sisters

6.
Does this pedigree show a dominant or recessive trait?
a)
Dominant
b)
Recessive
7.

What is the genotype for III-3?

(generation 3 individual 3)

a)

GG

b)

Gg

c)

gg

8.

What is the genotype for II-4?

(generation 2 individual 4)

a)

GG

b)

Gg

c)

gg

9.

The pedigree is showing a _____________ trait.

a)

autosomal dominant

b)

autosomal recessive

c)

sex linked recessive

10.
What is the genotype of the mother?
a)
BB
b)
bb
c)
Bb
d)
BB or Bb
11.
What is the genotype of the father?
a)
AA
b)
aa
c)
Aa
d)
AA or aa
12.

This is a __ trait.

a)

autosomal recessive

b)

sex-linked recessive

c)

autosomal dominant

13.

What is the mode of inheritance shown here?

a)

Sex Linked Recessive

b)

Autosomal Dominant

c)

Autosomal Recessive

14.

What is the mode of inheritance shown here?

a)

Autosomal Recessive

b)

Autosomal Dominant

c)

Sex Linked Recessive

15.
Hemophilia is a recessive sex-linked trait. If H = normal & h = has hemophilia, which genotype represents a male with hemophilia. 
a)
XHY
b)
XHXh
c)
XhXh
d)
Xh
16.
What percentage of the offspring will have this recessive disease?
a)
0%
b)
25%
c)
50%
d)
75%
17.

Colorblindness is a recessive X-linked disorder.

Which genotype represents a male with normal vision?

a)

XN YN

b)

Xn Yn

c)

XN Y

d)

Xn Y

18.
Which of the following genotypes belongs in the red box in the Punnett square?
a)
XBXb
b)
XbXb
c)
XbY
d)
XBY
19.
Which of the following genotypes belongs in the red box in the Punnett square, and what would the genotype be for the trait?
a)
XBX- female heterozygous
b)
XbX- female homozygous recessive
c)
XBX - female homozygous dominant
d)
XbY - male heterozygous recessive
20.

Duchenne muscular dystrophy is a recessive X-linked disorder.

According to the Punnett square, what percentage of offspring will have the disorder?

a)

0%

b)

25%

c)

50%

d)

100%

21.

Males are more likely to suffer from a sex-linked disease or disorder because...

a)

males are the weaker sex

b)

males have less DNA

c)

males have 1 X chromosome, so the disorder is more likely to be expressed

d)

females are the stronger sex

22.
How many affected females are present? 
a)
1
b)
2
c)
3
d)
4
23.

Which best explains why individual IV-7 has colorblindness?

a)

Because her mom is a carrier and her dad has the gene

b)

Because her dad has it.

c)

Because her siblings have it.

d)

Because her uncle has it.

24.

Is it possible for individual IV-2 to be a carrier for this autosomal trait? Why?

a)

No, because her parents don't have the trait.

b)

No, because she doesn't have the trait.

c)

Yes, because her siblings have it.

d)

Yes, because her parents are carriers.

25.

Give the genotype for person II-1, for this autosomal trait.

a)

GG

b)

Gg

c)

gg

d)

we cannot be 100% sure of the genotype