WorksheetsIS MODULE 4 ASSESSMENT
Total questions: 12
Worksheet time: 6mins
Which of the following is a general characteristic of
hypersensitivity reactions?
Immune responsiveness is depressed.
Antibody is involved in all reactions.
Either self-antigen or heterologous antigen may be
involved.
The antigen triggering the reaction is a harmful
one.
Which of the following is associated with an increase in
IgE production?
Transfusion reaction
Activation of Th1 cells
Reaction to poison ivy
HDN
Which of the following would cause a positive Direct Antiglobulin test?
Presence of IgG on red cells
Presence of C3b or C3d on red cells
A transfusion reaction due to preformed
antibody
Any of the above
All of the following are associated with type I hypersensitivity except
release of preformed mediators from mast cells.
activation of complement.
cell-bound antibody bridged by antigen.
an inherited tendency to respond to allergens.
Which newly synthesized mediator has a mode of action
similar to that of histamine?
LTB4
Heparin
ECF-A
PGD2
Which of the following is associated with anaphylaxis?
Buildup of IgE on mast cells
Activation of complement
Increase in cytotoxic T cells
Large amount of circulating IgG
To determine if a patient is allergic to rye grass, the best test to perform is
total IgE testing
skin prick test
DAT
complement fixation
Which condition would result in Hemolytic Disease of the Newborn/fetus?
Buildup of IgE on mother’s cells
Sensitization of cytotoxic T cells
Exposure to antigen found on both mother and
baby red cells
Prior exposure to foreign red cell antigen
What is the immune mechanism involved in type III
hypersensitivity reactions?
Cellular antigens are involved
Deposition of immune complexes occurs in antibody
excess
Only heterologous antigens are involved.
Tissue damage results from exocytosis.
What is the immune phenomenon associated with the
Arthus reaction?
Tissue destruction by cytotoxic T cells
Removal of antibody-coated red blood cells
Deposition of immune complexes in blood vessels
Release of histamine from mast cells
Contact dermatitis can be characterized by all of the
following except
formation of antigen–antibody complexes
generation of sensitized T cells
Langerhans cells acting as antigen-presenting cells.
complexing of a hapten to self-antigen
Which of the following explains the difference between
type II and type III hypersensitivity reactions?
Type II involves cellular antigens
Type III involves IgE
IgG is involved only in type III reactions
Type II reactions involve no antibody
