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Worksheets

Blood Group Systems

Total questions: 15

Worksheet time: 18mins

Name
Class
Date
1.

An antigen-antibody reaction alone does not cause hemolysis. Which of the following is required for red blood cell lysis?

a)

Albumin

b)

Complement

c)

G6PD

d)

Anti-human globulin

2.

Which of the following is a characteristic of the Kidd system antibodies?

a)

Usually IgM antibodies

b)

Corresponding antigens are destroyed by enzymes

c)

Usually strong and stable during storage

d)

Often implicated in delayed hemolytic transfusion reactions

3.

Most blood group antibodies are of what immunoglobulin type?

a)

IgA and IgD

b)

IgA and IgM

c)

IgE and IgD

d)

IgG and IgM

4.

Which of the following statements is not true of anti-Fya and anti-Fyb ?

a)

Are clinically significant

b)

React well with enzyme-treated panel cells

c)

Cause Hemolytic Transfusion reaction

d)

Cause a generally mild hemolytic disease of the newborn

5.

A patient's red blood cells are being typed for the Fya antigen. Which of the following is the proper cell type of choice for a positive control of the anti-Fya reagent?

a)

Fy(a+b-)

b)

Fy(a+b+)

c)

Fy(a-b+)

d)

Fy(a-b-)

6.

Which of the following antibodies has been clearly implicated in transfusion reactions and hemolytic disease of the newborn?

a)

Anti-I

b)

Anti-K

c)

Anti-Lea

d)

Anti-N

7.

Often when trying to identify a mixture of antibodies, it is useful to neutralize one of the known antibodies. Which one of the following antibodies is neutralizable?

a)

Anti-D

b)

Anti-Jka

c)

Anti-Lea

d)

Anti-M

8.

Which of the following antibodies does not match the others in terms of optimal reactive temperature?

a)

Anti-Fya

b)

Anti-Jkb

c)

Anti-N

d)

Anti-U

9.

Which set of antibodies could you possibly find in a patient with no history of transfusion or pregnancy?

a)

Anti-I, anti-s, anti-P1

b)

Anti-Leb, Anti-A1, anti-D

c)

Anti-M, anti-c, anti-B

d)

Anti-P1, anti-Lea, anti-I

10.

Which of the following is generally detected at the anti-human globulin phase of testing?

a)

Anti-Jka

b)

Anti-M

c)

Anti-P1

d)

Anti-I

11.

Which of the following blood group systems is associated with antibodies that are generally IgM?

a)

Rh

b)

Duffy

c)

Kell

d)

Lewis

12.

Which of the following statements best describes the MN antigens and antibodies?

a)

Well developed at birth, susceptible to enzymes, generally saline-reactive

b)

Not well developed at birth, susceptible to enzymes, generally saline-reactive

c)

Well developed at birth, not susceptible to enzymes, generally saline-reactive

d)

Well developed at birth, not susceptible to enzymes, generally AHG-reactive

13.

Which autoantibody specificity is found in patients with paroxysmal cold hemoglobinuria?

a)

I

b)

i

c)

P

d)

P1

14.

Which of the following is the most common antibody seen in the blood banks after ABO and Rh antibodies?

a)

Anti-Fyb

b)

Anti-k

c)

Anti-Jsa

d)

Anti-K

15.

Which blood group system is associated with resistance to P. vivax malaria?

a)

P

b)

Kell

c)

Duffy

d)

Kidd