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WorksheetsBB POST QUIZ MODULE 10 AND 11
Total questions: 22
Worksheet time: 31mins
A patient has Anti-E, which of the following donor genotype can be safely transfused to the patient?
R1R1
R2r’
r’r’’
RzR0
Donor serum has anti-c. To which of the following patient can his blood be given without expecting an adverse reaction?
DcE/dcE
DCe/Dce
R1r’
Rh: -1,2,-3,4,5
Which of the following is a possible genotype for an individual whose red cells give the reactions shown below?
Anti-D=3+; Anti-C= 2+; Anti-E=3+; Anti-c=3+; Anti-e=3+
R1R1
R1r’
R0r’’
R1R2
The patient’s genotype is R1R0. What antibody might this patient produce if transfused blood from a donor whose genotype is R2R0?
Anti-c
Anti-C
Anti-e
Anti-E
A donor is tested with Rh antisera, with the following results:
Anti-D=3+ Anti-C=0
Anti-E=2+ Anti-c=3+
Anti-e=3+ Rh control=0
Which of the following patient may be actively immunized if transfused blood from this donor genotype?
R1R1
R2r’’
R2ry
Rzr
A patient's red cells are typed as follows:
Anti-D=4+; Anti-C=0; Anti-E=0
Which of the following genotypes would correspond to this result?
R0R0
R1r
R1R2
R2r
A beta-thalassemic patient unexpectedly experienced a hemolytic transfusion reaction upon transfusing 2 units of pRBCs. A posttransfusion sample was requested for work-up. DAT was positive and sensitizing antibodies were eluted. Anti-E and anti-c were identified. Given his case, which among the following blood units may be safely given to him?
R0R0
ryr
r’R1
R2Rz
8. The Rh type of 35-year old male patient was given below
Anti-D=+; Anti-C=0; Anti-E=0 ; Anti-c=+; Anti-e=+
The blood factors present in his cells are
Rhorh’rh’’/rh’hr’’
hr’hr’’/Rh0hr’hr’’
Rh0rh’hr’’/rh’rh’’
hr’rh’’/rh’hr’’
What is the most probable Rosenfield phenotype of the patient whose Rh typing result is given below?
Anti-D=0; Anti-E=+; Anti-c=0; Anti-e=0
Rh: 1,2,-3,-4,5
Rh: -1,-2,3,-4,-5
Rh: -1,2,3,-4,-5
Rh: -1,3,-4,-5
Which of the following genotypes will demonstrate weak reaction with Anti-E but strong reaction with Anti-C?
Dce/dCE
DCe/DCE
DCe/DcE
dCe/dCe
Mutation in the RHCE locus will produce what phenotype?
Dce/Dce
dCE/dCE
D--/d--
-cE/-CE
Which among the following individuals must be transfused an Rh-positive blood?
Genetic weak D
RHDΨ/RHDΨ
Partial D
Del
Rh antibodies react best at______ and are mostly of _______isotype
37°C, IgM
22°C, IgM
37°C, IgG
22°C, IgG
The donor’s red cell failed to react with Anti-D upon completion of the IS phase. What must be done next?
Report as Rh(-)
Report as Rh(+)
Report as weak D positive
Incubate cells at 37°C and add AHG
Which set of reactions indicates homozygous inheritance of C allele and heterozygous inheritance of E/e alleles?
C = ___; c =____; E=____; e=_____
+ + + +
0 + + +
+ 0 + +
0 + 0 +
Which genes are defective in amorphic-type Rhnull syndrome?
RHAG only
RHCE, RHD
RHCE, RHAG
RHAG, RHCE, RHD
Which of the following phenotypes will not react with anti-LW?
DCE/DCE
dce/dce
D--/d--
Rh null (---/---)
“Blocked Rh” if not resolved, can potentially give a false-negative result. What must be done in order to prevent this anomaly?
Wash red cells the retype
Perform elution then retype
Perform lectin studies
Treat with DTT or 2-ME
A false-negative reaction in Rh typing may be encountered in
Patients with WAIHA
Patients with CAIHA
Newborns who are DAT (+)
Patients with autoimmune antibodies
Which Rh typing reagent is most prone to false positive result due to spontaneous agglutination?
Saline reactive reagents
High-protein Anti-D reagents
Chemically modified reagents
Monoclonal antibody reagents
A blood sample from a 30-year old pregnant woman revealed a positive Rosette test. A Kleihauer–Betke acid elution test was then performed and identified 67 fetal cells in 2,000 red cells counted.
a) What is the volume of fetomaternal hemorrhage?
b) How many full doses of RhIg should be indicated?
For answers just write the exact calculation . See example below on how to properly answer. (Round your answers to the nearest tens).
a) 300 L
b) 2 VIALS
(a)
If no rosettes were identified on fetomaternal hemorrhage screen. Is the mother eligible for RhIg? If yes, how many vials shall be given?
(a)
