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DD Lecture 2

Total questions: 10

Worksheet time: 3mins

Name
Class
Date
1.

Most drug targets are protein in nature

a)

Yes

b)

No

2.

Ligands never change the shape of their target

a)

True

b)

False

3.

Inhibitors act by changing the shape of the receptors

a)

True

b)

False

4.

Binding sites are usually hydrophilic

a)

True

b)

False

5.

Key and lock binding of ligands causes conformational changes

a)

True

b)

False

6.

Receptors must undergo conformational changes for activation

a)

True

b)

False

7.

For drugs to act as agonists, they must have the same shape and size as the natural messenger

a)

True

b)

False

8.

Enzyme inhibitors must not form stronger bonds than the natural substrate

a)

True

b)

False

9.

Allosteric modulators bind by key and lock fit

a)

True

b)

False

10.

Transport protein inhibitors have similar functional groups to those in neurotransmitters

a)

True

b)

False