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Integumentary System Review Quiz

Total questions: 100

Worksheet time: 50mins

Name
Class
Date
1.

Basal layer is responsible for the production of new cells

a)

True

b)

False

2.

Cells that detect deep pressure and vibration

a)

Free nerve endings

b)

Dermal Papillae

c)

Meissner's corpuscles

d)

Pacinian corpuscles

3.

Dermis is the deeper layer of the skin that develops from the mesenchyme

a)

True

b)

False

4.

Epidermal cell which is responsible for protection of the skin and underlying tissue from heat, microbes, and chemicals.

a)

Keratinocyte

b)

Langerhans cell

c)

Melanocyte

d)

Merkle cell

5.

Epidermis is the superficial layer of the skin that develops from the neural crest cells.

a)

True

b)

False

6.

Functions include Recognition, Uptake, Processing & Presentation of antigens to sensitized T lymphocytes.

a)

Melanocyte

b)

Langerhans cell

c)

Keratinocyte

d)

Neutrophil

7.

Granular layer consists of large polyhedral cells containing fine tonofibrils.

a)

True

b)

False

8.

Horny layer is made up of closely packed dead cells containing keratin

a)

True

b)

False

9.

Layer of the epidermis where the nucleus of the keratinocyte is shed.

a)

Stratum granulosum

b)

Stratum spinosum

c)

Stratum lucidum

d)

Stratum corneum

10.

Origin of the Melanocyte

a)

Neural Crest

b)

Mesenchyme

c)

Surface ectoderm

d)

Endoderm

11.

Regulate body temperature through evaporation (perspiration)

a)

Eccrine

b)

Apocrine

12.

Spinous layer contains small keratohyaline granules in its cells.

a)

True

b)

False

13.

The dermis is thickest at the

a)

back

b)

eyelids

c)

palms and soles (acral)

d)

face

14.

The layer of the epidermis which is uniquely found on acral skin.

a)

Stratum spinosum

b)

Stratum basale

c)

Stratum granulosum

d)

Stratum lucidum

15.

The skin and its associated structures, hair, nails, and glands are derived from the surface ectoderm.

a)

True

b)

False

16.

What is the congenital absence of hair?

a)

Hypertrichosis

b)

Ichthyosis

c)

Atrichia

d)

Vitiligo

17.

Condition in which accessory nipples have formed resulting from the persistence of fragments of the mammary line

a)

Polymastia

b)

Polythelia

c)

Inverted nipple

d)

Piebaldism

18.

globally reduced or absent pigmentation in the skin, hair and eyes.

a)

Vitiligo

b)

Albinism

c)

Waardenburg Syndrome

d)

Harlequin

19.

Condition in which the lactiferous ducts open into the original epithelial pit that has failed to evert

a)

inverted nipple

b)

polythelia

c)

polymastia

d)

exverted nipple

20.

Provides strength and flexibility to the skin

a)

Stratum granulosum

b)

Stratum spinosum

c)

Stratum basale

d)

Stratum lucidum

21.

Present only in the finger tips, palms of the hands and soles of the feet

a)

Stratum granulosum

b)

Stratum lucidum

c)

Stratum spinosum

d)

Stratum corneum

22.

Produces the pigment melanin which contributes to skin color and absorbs UV light

a)

Melanocyte

b)

Melansomes

c)

Keratinocytes

d)

Langerhans cell

23.

Detection of sensations of touch, shape and texture

a)

Meissner's corpuscles

b)

Pacinian corpuscles

c)

Mast cells

d)

Merkel cells

24.

Essential for discrimination of the fine spatial details

a)

Merkel cell

b)

Langerhans cell

c)

Mast cell

d)

Meissner's corpuscles

25.

At what week is the fetus covered by downy hair or lanugo

a)

25th week

b)

20th week

c)

30th week

d)

5th week

26.

The Stratum lucidum is present in the lips

a)

True

b)

False

27.

Which signaling pathway is implicated in differentiation of melanoblasts into melanocytes

a)

WNT

b)

TRP

c)

IL-1

d)

IL-2

28.

How many days does it take for skin to have cellular turnover?

a)

28

b)

10

c)

15

d)

22

29.

Large macule, 1 cm or greater in diameter

a)

patches

b)

papules

c)

vesicles

d)

wheals

30.

Evanescent, surrounded by a flare or macular erythema

a)

wheals

b)

vesicles

c)

papules

d)

macules

31.

Dried serum, pus or blood, usually mixed with epithelial and sometimes bacterial debris

a)

scales

b)

crusts

c)

pustules

d)

erosions

32.

Composed of new connective tissue that has replaced lost substance in the dermis or deeper parts resulting from injury or disease

a)

scars

b)

tumors

c)

ulcers

d)

scales

33.

Undergoes mitosis and enables skin to repair.

a)

Stratum basale

b)

Stratum spinosum

c)

Stratum granulosum

d)

Stratum corneum

34.

Found in Stratum spinosum and contains Birbeck granules.

a)

Langerhans cells

b)

Merkel cells

c)

Melanocytes

d)

Keratinocytes

35.

Which of the following is most implicated in skin squamous cell carcinoma?

a)

UVA

b)

UVB

c)

UVC

36.

Which structure is responsible for the formation of "goose skin"?

a)

collagen bundles

b)

connective tissue sheath

c)

arrector pili muscle

d)

external root sheath

37.

Peg-like projections of upper region of dermis

a)

adnexa

b)

dermal papillae

c)

callus

d)

arector pili

38.

Secretion that lubricates hair and skin

a)

sebum

b)

sweat glands

c)

sebaceous gland

d)

cerumen wax

39.

crescent white part of the nail

a)

lunula

b)

nail body

c)

nail root

d)

cuticle

40.

thin layer with keratinocytes become filled with keratin, flatten and lose their nuclei

a)

Stratum granulosum

b)

Stratum lucidum

c)

Stratum corneum

d)

Stratum spinosum

41.

Fungal infection of the nails

a)

Onychomycosis

b)

Onycholysis

c)

Onychomeiosis

42.

Instrumental in dispelling the theory of spontaneous generation of germs and proving that it existed.

a)

Louis Pasteur

b)

Joseph Lister

c)

Robert Wood Johnson

d)

Ignaz Semmelweis

43.

The first to differentiate between infected and diseased wounds compared to non-infected wounds.

a)

Sumerian

b)

Egyptian

c)

Edwin Smith

d)

Lister

44.

The 1st to use phenol in sterilizing instruments and the OR

a)

Pasteur

b)

Lister

c)

Semmelweis

d)

Smith

45.

Peak time of neutrophil invasion

a)

12-24H

b)

24-48H

c)

1 week

d)

48-96H

46.

Achieve significant numbers in the wound by 48 to 96H

a)

Neutrophil

b)

Macrophages

c)

Collagen

d)

Fibroblasr

47.

serves as scaffolding for the migration into the wound of inflammatory cells

a)

Platelet granule release

b)

Fibrin clot

c)

PMNs

d)

Macrophages

48.

The most abudant protein in the body

a)

TNF

b)

Collagen

c)

Proteoglycan

d)

Fibroblast

49.

Involves re-epithelization

a)

Primary intention

b)

Secondary Intention

c)

Tertiary Intention

50.

Greater degree of tissue loss and granulation tissue must be built

a)

Primary intention

b)

Secondary Intention

c)

Tertiary intention

d)

Delayed Intention

51.

A moist or even wet wound environment is critical to normal wound healing.

a)

True

b)

False

52.

Cell involved in 1 week post injury

a)

Macrophage

b)

PMN

c)

T lymphocyte

d)

Fibroblast

53.

major component of extracellular matrix in the skin

a)

Type I collagen

b)

Type II collagen

c)

Type III collagen

54.

Becomes more prominent and important during the repair process

a)

Type I collagen

b)

Type II collagen

c)

Type III collagen

55.

Phase where coagulation cascade occurs.

a)

Hemostasis and inflammation

b)

Proliferation

c)

Maturation and Remodelling

56.

Collagen lends ______ to the skin

a)

Color

b)

Structure

c)

Elasticity

d)

UV protection

57.

The papillary layer of the dermis is most closely assoc. with which layer of epidermis

a)

Stratum spinosum

b)

Stratum basale

c)

Stratum corneum

d)

Stratum granulosum

58.

The papillary and reticular layers of the dermis are composed mainly of ______.

a)

melanocytes

b)

keratinocytes

c)

connective tissue

d)

adipose tissue

59.

Which of the following is not a function of the hypodermis

a)

Protects underlying organs

b)

Helps maintain body temperature

c)

Source of blood vessels in the epidermis

d)

Site to long term energy storage

60.

In response to stimuli from the Sympathetic nervous system, the arrector pili ________.

a)

are glands on the skin surface

b)

can lead to excessive sweating

c)

are responsible for goosebumps

d)

secrete sebum

61.

The hair matrix contains

a)

hair follicle

b)

hair shaft

c)

glassy membrane

d)

layer of basal cells

62.

Eccrine sweat glands ________.

a)

are present on hair

b)

are present in the skin throughout the body and produce watery sweat

c)

produce sebum

d)

act as a moisturizer

63.

Sebaceous glands are

a)

associated with hair follicles

b)

type of sweat gland

c)

may function in response to touch

d)

release a watery solution of salt and metabolic waste

64.

Similar to the hair, nails grow continuously throughout our lives. Which of the following is furthest from the nail growth center?

a)

nail bed

b)

hyponychium

c)

nail root

d)

eponychium

65.

whitish paste; protects kin against macerating action of amniotic fluid

a)

vernix caseosa

b)

lanugo

c)

corium

d)

dermal root

66.

Characterized by thick adherent silvery scales with marked underling erythema.

a)

Lichen simplex chronicus

b)

Psoriasis vulgaris

c)

Pityriasis rosea

d)

Tinea corporis

67.

Atopic Dermatitis has ___ stages

a)

3

b)

2

c)

1

d)

4

68.

Clustered thin walled vesicles in a dermatomal distribution

a)

Herpes Simplex

b)

Herpes Zoster

c)

Varicella

d)

Pemphigus

69.

Dew drop on a rose petal appearance

a)

chicken pox

b)

measles

c)

acne

d)

shingles

70.

Loss of melanocytes secondary to immunologic activity

a)

vitiligo

b)

tinea versicolor

c)

nevi

d)

ephelides

71.

Has a significant correlation with neurofibromatosis

a)

Nevi

b)

Cafe au lait

c)

Basal cell carcinoma

d)

Ephelides

72.

sclerotic disorder that involves areas beyond the initial injury

a)

hypertrophic scars

b)

keloids

c)

alopecia areata

d)

scarring alopecia

73.

Abnormal shedding and accumulation of the stratum corneum in perceptible flakes

a)

acne

b)

eczema

c)

pruritis

d)

scale

74.

facial ringworm

a)

tinea corporis

b)

tinea faciei

c)

tinea pedis

d)

tinea manuum

75.

fine scaling at periphery of lesion

a)

herald patch

b)

collarette

c)

skin asthma

d)

crust

76.

Phases of Chicken pox lesion

a)

pustular --> vesicular --> necrotic

b)

necrotic -> pustular --> vesicular

c)

vesicular --> pustular --> necrotic

77.

Honey colored crust lesions

a)

impetigo

b)

furuncles

c)

folliculitis

d)

carbuncle

78.

fluid filled lesion

a)

bullae

b)

ichthyosis

c)

edema

d)

erythema

79.

Relieved by dependence, aggravated by elevation

a)

Arterial ulcer

b)

Venous ulcer

c)

Capillary ulcer

80.

Relieve by elevation, aggravated by dependence

a)

Arterial ulcer

b)

Venous ulcer

81.

triggered by trauma, stress or sunburn

a)

herpes simplex

b)

herpes zoster

c)

varicella

d)

rubella

82.

Most common skin cancer worldwide

a)

melanoma

b)

basal cell CA

c)

squamous cell CA

d)

merkel cell CA

83.

hand ringworm

a)

tinea corporis

b)

tinea manuum

c)

tinea pedis

d)

tinea faciei

84.

Associated with allergic rhinitis, hay fever and skin hyperactivity

a)

atopic dermatitis

b)

contact dermatitis

85.

Painful genital ulcerative disorder

a)

syphilis

b)

chancroid

c)

chancre

d)

impetigo

86.

usually occurs 30% post partum after 3-6 months

a)

Telogen effluvium

b)

Anagen effluvium

c)

Alopecia areata

d)

Hirsutism

87.

creamy white or off white patches

a)

tinea corporis

b)

tinea versicolor

c)

tinea pedis

d)

tinea manuum

88.

easily rupture leaving large eroded surfaces

a)

pemphigus

b)

epidermal necrolysis syndrome

c)

steven johnson syndrome

d)

epidermis pustular disorder

89.

fishlike/ platelike scales

a)

lamellar ichthyosis

b)

ichthyosis vulgaris

c)

lichenoid disorder

d)

psoriasis vulgaris

90.

also play significant role in regulating angiogenesis and matrix deposition and remodelling

a)

macrophages

b)

T-lymphocytes

c)

neutrophil

d)

fibronectin

91.

Factors of systemic wound healing except for

a)

nutrition

b)

edema

c)

trauma

d)

smoking

92.

Wound edge are not approximated

a)

Primary intention

b)

Secondary intention

c)

Tertiary intention

d)

Delayed intention

93.

Lower risk of infection and minimal scarring

a)

Primary intention

b)

Secondary intention

c)

Tertiary intention

d)

Delayed intention

94.

precedes and initiates inflammation with the ensuing release of the chemotactic factors from the wound site

a)

hemostasis

b)

remodelling

c)

proliferation

d)

maturation

95.

Caused of delayed healing EXCEPT

a)

nutritional deficiency

b)

moist environment

c)

infection

d)

severe trauma

96.

Usual mechanism for the formation of a chronic wound.

a)

acute wound phase

b)

protracted inflammatory phase

c)

reverse infection phase

d)

phagocytosus

97.

8-10 cell layers held together by desmosomes

a)

Stratum lucidum

b)

Stratum basale

c)

Stratum spinosum

d)

Stratum granulosum

98.

Stretchmarks are dermal tears from mild stretching

a)

TRUE

b)

FALSE

99.

inhibits excessive loss of water and urea

a)

TRUE

b)

FALSE

100.

it provides most the hair's weight.

a)

cuticle

b)

cortex

c)

medulla

d)

follicle