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HEMA 2 ASSESSMENT MODULE 2.2

Total questions: 25

Worksheet time: 13mins

Name
Class
Date
1.

It is a genetic mutation more prevalent in people European descent that causes hypercoagulability.

a)

Leiden

b)

DIC

c)

Vit. K Deficiency

d)

vonWillebrand's Disease

2.

OWREN’s Disease is aka as ______________ deficiency.

a)

Factor I

b)

Factor II

c)

Factor V

d)

Factor II

3.

What is the typical treatment for vitamin K deficiency when

the patient is bleeding?

a)

Vitamin K and Platelet Concentrate

b)

Vitamin K and plasma

c)

Vitamin K and platelet concentrate

d)

Vitamin K and factor VIII concentrate

4.

Which of the following conditions causes a prolonged

thrombin time?

a)

Antithrombin deficiency

b)

Prothrombin deficiency

c)

Hypofibrinogenemia

d)

Warfarin therapy

5.

Detects factor deficiency in the common pathway.

a)

Russel Viper Venom time

b)

PT

c)

aPTT

d)

Thrombin time

6.

Normal Value for aPTT

a)

10-12 secs

b)

25-35 secs

c)

5-10 secs

d)

2-4 secs

7.

Measures rate of thrombin-induced cleavage of fibrinogen to fibrin monomers and subsequent polymerization to form insoluble fibrin clot

a)

aPTT

b)

Stypven time

c)

PT

d)

Thrombin time

e)

Duckert's test

8.

Normal Value for PT

a)

10-12 secs

b)

25-35 secs

c)

5-10 secs

d)

2-4 secs

9.

This laboratory test is mostly affected by Heparin therapy.

a)

Thrombin time

b)

apTT

c)

PT

d)

Stypven time

10.

Detects factor XIII deficiency

a)

aPTT

b)

Stypven time

c)

PT

d)

Thrombin time

e)

Duckert's test

11.

Coagulation disease common in Eastern European Jewish descent or ASHKENAZI JEWS.

a)

vWD

b)

Hemophilia A

c)

Hemophilia B

d)

Hemophilia C

e)

Fletcher trait

12.

This enzyme is an important component in coagulation factor production because it helps recycle Vitamin K

a)

Heparin

b)

Thrombospondin

c)

Transglutaminase

d)

Epoxide reductase

13.

A fibrinolytic inhibitor that forms a complex with thrombin, kallikrein and plasma inhibiting their activities.

a)

Protein C

b)

Protein S

c)

Heparin Cofactor II

d)

Alpha2-macroglobulin

14.

This test is used because it is not affected in patients undergoing heparin therapy.

a)

Duckert's test

b)

Thrombin Time

c)

Clotting Time

d)

Stypven time

e)

Reptilase time

15.

Which factor deficiency would cause prolong PT and aPTT?

a)

Factor V

b)

Factor VII

c)

Factor VIII

d)

Factor XII

16.

Which factor deficiency would cause prolong aPTT but normal PT?

a)

Factor V

b)

Factor VII

c)

Factor X

d)

Factor IX

17.

Which factor deficiency would cause prolong PT but normal APTT?

a)

Factor V

b)

Factor VII

c)

Factor X

d)

Factor IX

18.

Which condition causes prolong coagulation tests except for Duckert's test?

a)

Parahemophilia

b)

vWD

c)

DIC

d)

Hemophilia

19.

It is considered major inhibitor of fibrinolysis and the first to bind the plasmin.

a)

Alpha-1 antitrypsin

b)

alpha 2-macroglobulin

c)

alpha-2-antiplasmin

d)

Thrombospondin

20.

A fibrinogen degradation product that is a powerful inhibitor of thrombin.

a)

X & Y

b)

D & E

c)

E

d)

Y& D

21.

What test may be used to confirm the presence of LA?

a)

PT

b)

Bethesda titer

c)

Antinuclear antibody

d)

PTT using high-phospholipid reagent

22.

What therapeutic agent may occasionally cause DIC?

a)

Factor VIII

b)

Factor VIIa

c)

Antithrombin concentrate

d)

Activated prothrombin complex concentrate

23.

Which is not a fibrinolysis control protein?

a)

Thrombin-activatable fibrinolysis inhibitor

b)

Plasminogen activator inhibitor-1

c)

a2-antiplasmin

d)

D-dimer

24.

Which of the following is absent in Fresh serum?

a)

Factor XIII

b)

Factor VII

c)

Factor X

d)

Factor XII

25.

Which factor is absent in Adsorbed plasma that is absent in Aged Plasma.

a)

I

b)

II

c)

VII

d)

X

e)

XI