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Worksheets

Exam II

Total questions: 20

Worksheet time: 12mins

Name
Class
Date
1.

All of the following are part of the nucleosome, except...

a)

H2A

b)

H3

c)

H2B

d)

H1

2.

Euchromatin is...

a)

Condensed and inaccessible

b)

Condensed and accessible

c)

Decondensed and inaccessible

d)

Decondensed and accessible

3.

Which is the third order of chromatin structure?

(a)  

4.

This type of chromatin can interconvert from euchromatin to heterochromatin and vice versa

a)

Facultative heterochromatin

b)

Constant heterochromatin

c)

Constant euchromatin

d)

Chromatin fiber

5.

What is absolutely necessary for transcription to occur (without it, transcription would never occur)?

(a)  

6.

Where do we find the TATA box?

a)

Cis-acting sequence

b)

Enhancer

c)

Silencer

d)

Promoter

e)

All are correct

7.

What protein binds to the enhancer resulting in an optimal level of transcription?

a)

Silencer

b)

Activator

c)

Repressor

d)

Importin

8.

Repressors prevent the formation of what?

a)

Promoter

b)

Enhanceosome

c)

Spliceosome

d)

Ribosome

9.

Gene methylation leads to the activation of a gene.

a)

True

b)

False

10.

This enzyme adds acetyl groups to histone tails to make DNA accessible

a)

HDACs

b)

Kinase

c)

HATs

d)

RATs

11.

Which three amino acids can be phosphorylated?

a)

Serine

b)

Threonine

c)

Tryptophan

d)

Tyrosine

12.

What type of regulation is used when histones are hiding the promoter?

a)

Acetylation

b)

DNA methylation

c)

Nucleosome remodeling

d)

Phosphorylation

13.

If gene 1 has deacetylated histone tails and gene 2 has methylated histone tails, which of the two would be transcribed more efficiently? (assuming that these are the only modifications they have)

a)

Gene 1

b)

Gene 2

c)

Both

d)

Neither gene would be efficiently transcribed

14.

Epigenetics are heritable changes in gene expression caused by the DNA sequence itself.

a)

True

b)

False

15.

Gene methylation occurs in...

a)

Histone tails

b)

CpG regions

c)

Promoter

d)

Cis-acting sequence

16.

Alternative splicing allows for a greater diversity of proteins obtained from one mRNA.

a)

True

b)

False

17.

Which of the following prolong the half-life of the mRNA?

a)

Enhancer

b)

5' cap

c)

Poly-A tail

d)

Nucleases

18.

How does the RISC complex regulate translation if there's 100% match between the miRNA and the mRNA?

a)

Hiding mRNA in P-bodies

b)

Blocking DNA accessibility

c)

Cleaving the mRNA

d)

Allows translation to occur

19.

Which complex regulates transcription as the new mRNA transcript is being made?

a)

RISC

b)

RITS

c)

Transcription factor complex

20.

Phosphorylation of which enhances translation globally?

a)

eIF2

b)

eIF4

c)

eEF2

d)

eEF1