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WorksheetsCell Communication
Total questions: 12
Worksheet time: 21mins
When a signal molecule arrives at the appropriate G protein-coupled receptor, the receptor changes its conformation, a GTP binds to the alpha subunit, and the G protein alpha and beta/gamma subunits _____________ .
come together to form an alpha/beta/gamma complex
separate and are both active
are inactivated and then separate
bind to calcium Ca++ and open Calcium ion channels
Where does the ligand bind to initiate signal transduction?
glycolipids
nucleus
phosphorylation cascade
receptor
Which of the following is the order of steps for a signal transduction pathway?
Transduction -> Response
Reception -> Initiation -> Transduction -> Response
Reception -> Transduction -> Response
Transduction -> Reception -> Response
Which of the following is a potential response for the cell?
Conformational Change of the ligand
Transcription Factor
Phosphorylation Cascade
Release of Ca2+ from Smooth ER
Insulin released from a pancreatic islet cell can travel through the blood stream to act on muscle and liver cells. This is an example of ______________signaling.
neuronal
endocrine
paracrine
autocrine
contact dependent
Paracrine signaling is
Local Signaling
Long distance signaling through the bloodstream
Signals sent to cells through gap junctions
a signal that cells send to themselves
The G-Protein Couple Receptor is a Multi-pass membrane protein that passes through the membrane ______ times.
1
2
4
7
9
The alpha subunit of the G protein has GTPase activity which means that when ______ is attached the protein is ________ .
GTP : active
GDP : inactive
GTP : inactive
GDP : active
