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Molecular Docking

Total questions: 8

Worksheet time: 4mins

Name
Class
Date
1.

Which is not part of CADD steps....

a)

a. Target Identification

b)

b. Target Validation

c)

c. Target Optimization

d)

d. Lead Discovery

2.

Which of the following is not include to computer-aided drug discovery for lead discovery....

a)

a. Library design

b)

b. Docking scoring

c)

c. Target Flexibility

d)

d. Target druggability

3.

Which protein that should be inhibited to weaken the virus?

a)

a. Aglutinin protein

b)

b. Hemaglutinin protein

c)

c. Endosol protein

d)

d. genetic material

4.

These followings are the part of SARS-Cov 2, except.

a)

a. spike glycoprotein

b)

b. protein membrane

c)

c. envelope membrane protein

d)

d. genomic DNA

5.

Which of the following is a COVID-19 drug candidate?

a)

a. Nigellamine A2

b)

b. Nigellamine A5

c)

c. Nigellamine A8

d)

d. Taraxerol

6.

Which one is not the key aspect of docking....

a)

a. Scoring function

b)

b. Search methods

c)

c. Dimensionality

d)

d. Molecular size

7.

Drugs candidate can be attached to protein target via mechanism below, except?

a)

a. phi phi stacking

b)

b. hidrophobic

c)

c. metal binding

d)

d. hidrogen binding

8.

Which of the following is not an application of computational methods in drug discovery?

a)

a. QSAR

b)

b. Molecular Docking

c)

c. Cell line testing

d)

d. Virtual Screening