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WorksheetsCh 10 Microbiology
Total questions: 25
Worksheet time: 13mins
Beta-lactam antibiotics have an effect on which of the following types of cells?
animal cells
bacterial cells
viral infected cells
fungal cells
External infections can be treated by _____ administration, in which a drug is applied directly to the site of infection.
topical
intramuscular
oral
intravenous
Disruption of the normal microbiota can result in infections caused by which of the following microbes?
Clostridium difficile
Candida albicans, Mycobacterium, and Clostridium difficile
Candida albicans
Mycobacterium
Leprosy can be treated with _____.
Valtrex
AZT
Penicillin
Dapsone
A(n)_____ concentration of a drug is one at which microbes survive but are not able to grow and reproduce.
bactericidal
germicidal
bacteriostatic
virucidal
Metronidazole is used to treat _____.
Listeria and Syphilis
Trichomonas and H. pylori
Gonorrhea and Staph
Staph and strep
Most broad-spectrum antibiotics act by
disrupting the cytoplasmic membrane
inhibiting protein synthesis
inhibiting nucleic acid synthesis
inhibiting synthesis of the cell wall
The antimicrobials called quinolones act by
inhibiting cell wall synthesis
inhibiting protein synthesis
inhibiting nucleic acid synthesis
disrupting cytoplasmic membranes
Which of the following statements is true of selective toxicity?
Antimicrobial agents must target structural differences between host and pathogen and be more toxic to the patient than the pathogen.
Selective toxicity takes advantage of structural and/or metabolic differences between host and pathogen.
Selective toxicity tries to kill the host but not the pathogen.
To be effective, an antimicrobial agent must be more toxic to the patient than the pathogen.
The most limited group of antimicrobial agents is the _____drugs.
antiprotozoan
antifungal
antibacterial
antiviral
Ivermectin is used to treat _____.
bacteria
Helminths
fungi
viruses
Beta lactamase production is an example of which of the following types of resistance?
alteration of the target of the drug
inactivation of the drug
Second-generation drugs are semisynthetic drugs developed to combat _____ against an existing drug.
resistance
immunity
toxicity
topical
Which of the following is a primary advantage of semisynthetic drugs?
They have fewer side effects.
They work faster.
They have a broader spectrum of action.
They are less stable.
Metronidazole is also known as Flagyl.
True
False
Who discovered the first widely available antibiotic?
Fleming
Ehrlich
Ehrlich and Fleming
Domagk
Secondary infections that result from the killing of the normal microbiota are called
virulent
pathogenic
toxic
superinfections
Infection of the _____would be the hardest to treat with antimicrobial drugs.
kidneys
brain
colon
heart
Valaciclovir is used to treat
Staph
Gonorrhea
Strep
Herpes
Which of the following groups of drugs can become incorporated into the bones and teeth of a fetus?
tetracyclines
quinolones
beta-lactams
sulfonamides
Vancomycin is effective in treating MRSA.
True
False
Organs that are commonly affected by drug toxicity include the kidneys and the liver.
True
False
Selective _____ means that a given antimicrobial agent is more toxic to a pathogen than to the host being treated.
bacteriostatic
drug
toxicity
chemotherapeutic
It is inappropriate to prescribe antibacterial agents to treat colds or flu because
these diseases are caused by viruses
these diseases can act synergistically with each other
the microbes involved can develop resistance rapidly
these diseases exhibit cross resistance
Chloroquine and Artmisinin are used to treat _____.
Staph
Herpes
Malaria
HIV
