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WorksheetsMedical Micro 6: Cardiovascular
Total questions: 104
Worksheet time: 59mins
Most infections in the heart occur in the
pericardium
endocardium
valves
bacterial infection of the bloodstream (systemic infection)
septicemia
lymphangitis
bacteremia
infection of the lymphatic system
septicemia
lymphangitis
bacteremia
transient bacteria in the bloodstream
septicemia
lymphangitis
bacteremia
diagnosis of septicemia includes
coma
change in mental status
low WBC
SBP < 100
RR > 22
Sepsis is the body's response to septicemia
True
False
Every hour you delay antibiotic therapy in septic shocks patients, chance of death increases
True
False
Correct chain of events leading to sepsis and septic shock
1) Endotoxin/Exotoxin Accumulation
2) Septicemia
3) Localized infections
1) Septicemia
2) Localized Infections
3) Endotoxin/Exotoxin Accumulation
1) Localized Infections
2) Endotoxin/Exotoxin Accumulation
3) Septicemia
1) Localized Infections
2) Septicemia
3) Endotoxin/Exotoxin Accumulation
affects the endocardium and heart valves
infective endocarditis
septicemia
streptococcal infections
schistosomiasis
Causative agent(s) for acute endocarditis
Staphylococcus aureus
Streptococcus pneumoniae
Neisseria gonorrhoeae
Stretococcus pyogenes
Enterococcus faecalis
Signs/symptoms of this endocarditis include high fever, fast heart rate, fatigue, and signs of infections at other sites:
Acute
Subacute
Prosthetic
Causative agent(s) for subacute endocarditis:
Streptococcus
Staphylococcus
Haemophilus
Enterococcus
Underlying heart valve disease
Acute endocarditis
Subacute endocarditis
Prosthetic endocarditis
Treatment for this endocarditis includes surgery, likely a valve replacement:
Acute
Subacute
Prosthetic
Streptococcal infections cannot affect the cardiovascular systems
True
False
Causative agent(s) for Puerperal fever (childbed fever)
S. pyogenes
S. agalactiae
E. coli
Causative agent(s) of Neonatal sepsis
S. pyogenes
S. agalactiae
E. coli
Causative agent(s) of Rheumatic fever:
S. pyogenes
S. agalactiae
E. coli
Inflammatory response to the throat infection and primarily affects the joints and heart
Puerperal fever
Neonatal sepsis
Rheumatic fever
The worms that cause schistosomiasis are found in the United States
True
False
Major effects in Schistosoma are due to snail eggs in the:
Liver
Intestines
Bladder
Schistosoma is transmitted by
Snails
Mosquitoes
In filariasis, larvae infect the
lymphatic system
cardiovascular system
Filariasis is transmitted by
Snails
Mosquitoes
Filariasis is caused by
Yersinia pestis
Wuchereria bancrofti
Neisseria gonorrhoeae
Enterococcus faecalis
Causative agent of the Plague ("The Black Death"):
Yersinia pestis
Wuchereria bancrofti
Neisseria gonorrhoeae
Enterococcus faecalis
Yersinia pestis
Facultative
Gram-neg rod
Gram-pos rod
bipolar staining
spore forming
Bacteria localize in lymph nodes, painful and substantial swelling, transmitted through the bite of an infected flea or exposure to infected material through a break in the skin, dark splotches on skin from bleeding:
Bubonic plague
Septicemic plague
Pneumonic plague
Bacilli spread to the bloodstream, high fever, diarrhea, abdominal pain, can lead to meningitis and nearly 100% fatal if untreated:
Bubonic plague
Septicemic plague
Pneumonic plague
transmitted from person to person (from coughing), buboes are not present
Bubonic plague
Septicemic plague
Pneumonic plague
Tularemia is transmitted via
person to person (coughing)
arthropod bite (ticks)
Tularemia (Rabbit fever) treatment:
streptomycin
oral ciprofloxacin
doxycycline
penicillin
Disease(s) caused by spirochetes:
Plague
Tularemia
Lyme Disease
Relapsing fever
Causative agent of lyme disease:
Yersinia pestis
Wuchereria bancrofti
Neisseria gonorrhoeae
Borrelia burgdorferi
Symptoms of lyme disease
fever
headache
fatigue
change in mental status
erythema migrans
This stage of lyme disease involves a slowly expanding red rash (erythema migrans) at the bite site, resembles a bull's-eye, accompanied by flu like symptoms:
Early localized stage
Early disseminated stage
Late stage
This stage of lyme disease begins weeks to months later and bacteria disseminated to the skin, heart, and nervous system:
Early localized stage
Early disseminated stage
Late stage
This stage of lyme disease occurs months to years later and involves chronic arthritis with swelling in the larger joints:
Early localized stage
Early disseminated stage
Late stage
Treatment includes 10 days of doxycycline
Early localized stage
Early disseminated stage
Late stage
Treatment includes 28 days of doxycycline
Early localized stage
Early disseminated stage
Late stage
Causative agent(s) of Endemic relapsing fever
Borrelia hermisii
Borrelia turicatae
Borrelia recurrentis
Causative agent of Louseborne (epidemic) relapsing fever
Borrelia hermisii
Borrelia turicatae
Borrelia recurrentis
Endemic relapsing fever is transmitted via
ticks from rodents
body lice
mosquitoes
snails
Louseborne (epidemic) relapsing fever is transmitted via
ticks from rodents
body lice
mosquitoes
snails
Symptoms of relapsing fever
fever
chill
headache peak
erythema migrans
high numbers of microorganisms in blood
Treatment of relapsing fever without CNS involvement:
doxycycline
penicillin
ceftriaxone
Treatment of relapsing fever with CNS involvement:
doxycycline
penicillin
ceftriaxone
Causative agent of Brucellosis:
Brucella species
Rickettsia rickettsia
Causative agent of Rocky Mountain spotted fever (RMSF) or Spotted Fever Rickettsiosis (SFR)
Brucella species
Rickettsia rickettsia
Brucella species are
Gram negative
Gram positive
coccus
rods
This disease has a specific fever pattern of sweats in the day, chills at night:
Brucellosis
Rocky Mountain spotted fever (RMSF)
Human monocytic ehrlichiosis (HME)
Human granulocytic anaplasmosis (HGA)
Infection can occur through eyes, abrasions, or consumption of contaminated dairy products and has a 2-10 week incubation:
Brucellosis
Rocky Mountain spotted fever (RMSF)
Human monocytic ehrlichiosis (HME)
Human granulocytic anaplasmosis (HGA)
The bacteria of this disease are transported to the spleen and lymph glands:
Brucellosis
Rocky Mountain spotted fever (RMSF)
Human monocytic ehrlichiosis (HME)
Human granulocytic anaplasmosis (HGA)
This disease can cause chronic infection in one organ or systemically, complications include endocarditis:
Brucellosis
RMSF
HME
HGA
Treatment for Brucellosis:
Penicillin (10 days)
Gentamicin (7-10 days)
Doxycycline (6 weeks)
Fluconazole (for life)
Rickettsiae
small
large
gram negative
gram positive
obligate intracellular parasites
RMSF or SFR is transmitted via
hard ticks
lone star tick
blacklegged tick
HME is transmitted via
hard ticks
lone star tick
blacklegged tick
HGA is transmitted via
hard ticks
lone star tick
blacklegged tick
Symptoms of RMSF/SFR include:
high fever
headache
chills
fatigue
maculopapolar rash
Clinical presentation of HME includes:
acute febrile illness
myalgia
arthralgias
malaise
maculopapular rash
Leukocytes are infected and a lowering of white blood cell count (leukopenia) is seen in this disease:
Brucellosis
RMSF
HME
HGA
Doxycycline is the treatment
RMSF
SFR
HME
HGA
What would distinguish from RMSF and ehrlichiosis
White blood count
Antibody test
Strep test
Oxygen levels
Red blood count
Treatment is available for infectious mononucleosis (mono)
True
False
Individuals with preexisting cardiovascular disease are at increased risk for morbid and mortal complications due to COVID-19.
True
False
Largest member of herpesviridae
Cytomegalovirus (CMV)
Epstein-Barr virus (EBV)
The virus may pass into the fetus of a pregnant woman, causing mental impairment
Cytomegalovirus (CMV)
Epstein-Barr virus (EBV)
Member of TORCH microbes that cross the placenta to cause severe congenital defects
Cytomegalovirus (CMV)
Epstein-Barr virus (EBV)
Spread by contact with saliva
Cytomegalovirus
Infectious mononucleosis
Burkitt lymphoma
Causative agent of infectious mononucleosis (mono)
Cytomegalovirus (CMV)
Epstein-Barr virus (EBV)
Causative agent of Burkitt lymphoma
Cytomegalovirus (CMV)
Epstein-Barr virus (EBV)
Tumor of the jaw prevalent in Africa
Cytomegalovirus
Infectious mononucleosis
Burkitt lymphoma
Complications of mono include:
Jaundice
Black vomit
Myocarditis
Guillain-Barre
Spleen rupture
Passed from person to person via mosquitoes:
Flaviviruses
Yellow Fever
Dengue Virus
Lassa Fever
Ebola hemorrhagic fever
Dengue virus occurs in 3 types
True
False - 1 type
False - 2 types
False - 4 types
Recovery from one type of Dengue Virus does not confer immunity to other types
True
False
Two vaccines are available, but no therapeutic drugs
Flavivirus
Yellow Fever
Dengue Virus
Lassa Fever
Ebola hemorrhagic fever (EHF)
Treatment is more supportive (control blood pressure), no antiviral for this:
Flavivirus
Yellow Fever
Dengue Virus
Lassa Fever
Ebola hemorrhagic fever (EHF)
Transmitted via rodents that carry virus, human infected via contact with urine or droppings
Flavivirus
Yellow Fever
Dengue Virus
Lassa Fever
Ebola hemorrhagic fever (EHF)
Hemorrhagic viruses:
Flavivirus
Yellow Fever
Dangue Virus
Lassa Fever
Ebola hemorrhagic fever (EHF)
Ribavirin is an effective treatment; to decrease mortality, implement treatment early
Flavivirus
Yellow Fever
Dangue Virus
Lassa Fever
Ebola hemorrhagic fever (EHF)
Members of the _____ produce severe hemorrhagic lesions of the tissues
Herpesviridae
Filoviridae
Appears to be zoonotic, with fruit bats as a possible reservoir. Transmission can occur with contact with blood or secretions from and infected person or contaminated objects:
Flavivirus
Yellow fever
Dangue virus
Lassa fever
Ebola hemorrhagic fever (EHF)
Who is most susceptible to malaria?
Children
Adults
Elderly
Species of Plasmodium that cause malaria:
P. vivax
P. ovale
P. malariae
P. falciparum
P. knowlesi
Malaria death can occur due to:
Internal hemorrhaging
Secondary infection
Severe dehydration
Loss of RBCs
RBC clustering in small vessels
Treatment drug of choice is doxycycline
Babesiosis
Trypanosomiasis
Epidemic typhus
Brill-Zinsser disease
Endemic typhus
Also known as typhus fever
Epidemic typhus
Endemic typhus
Also known as Mexican typhus or murine typhus
Epidemic typhus
Endemic typhus
Causative agent of Endemic typhus
B. microti
T. brucei
T. cruzi
R. typhi
R. prowazekii
Causative agent of Epidemic typhus:
B. microti
T. brucei
T. cruzi
R. typhi
R. prowazekii
Causative agent of Chagas disease
B. microti
T. brucei
T. cruzi
R. typhi
R. prowazekii
Causative agent of Human African sleeping sickness
B. microti
T. brucei
T. cruzi
R. typhi
R. prowazekii
Causative agent of Babesiosis
B. microti
T. brucei
T. cruzi
R. typhi
R. prowazekii
Malaria like disease that is transmitted by ticks, where parasites invade RBCs:
Babesiosis
Human African sleeping sickness
Chagas disease
Epidemic typhus
Endemic typhus
Trypanosomiasis is the name for 2 diseases caused by species of Trypanosoma and those 2 diseases are:
Babesiosis
Human African sleeping sickness
Chagas disease
Epidemic typhus
Endemic typhus
Transmitted by tsetse fly, chancre forms at the bite site, and parasites invade the bloodstream and then central nervous system
Babesiosis
Human African sleeping sickness
Chagas disease
Epidemic typhus
Endemic typhus
Treatment of malaria
Doxycycline
Chloroquine
Penicillin
No treatment exists
Transmitted by reduviid bug (insect) and damages intestinal tract and cardiac nerve (sudden heart failure)
Babesiosis
Human African sleeping sickness
Chagas disease
Epidemic typhus
Endemic typhus
Transmitted by feces of body lice that flourish when sanitation and hygiene is poor
Babesiosis
Human African sleeping sickness
Chagas disease
Epidemic typhus
Endemic typhus
Transmitted by oriental rat fleas
Babesiosis
Human African sleeping sickness
Chagas disease
Epidemic typhus
Endemic typhus
Brill-Zinsser disease appears to be a relapse (years later) of:
Epidemic typhus
Endemic typhus
Transmitted by one of two species of mosquito
Flavivirus
Yellow Fever
Dangue Virus
Lassa Fever
Ebola hemorrhagic fever (EHF)
