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HKKN Practice test

Total questions: 45

Worksheet time: 45mins

Name
Class
Date
1.

The living state is

a)

Non-equilibrium unsteady–state

b)

Equilibrium steady–state

c)

Non-Equilibrium steady-state unable to perform work

d)

Non-equilibrium steady-state to be able to perform work

2.

Rate of a chemical reaction can be expressed as

Rate= δP/ δT

Where δP represents

a)

Product formed per unit time

b)

Product formed in total time δt

c)

Reactants present at the beginning of reaction

d)

Amount of reactants which changes into products in unit time

3.

Zinc is a cofactor for an enzyme which breaks peptide bonds present at C-terminal of peptides. The enzyme is

a)

Carboxypeptidase

b)

Aminopeptidase

c)

Carbonic anhydrase

d)

Peroxidase

4.

Food is one of the basic requirement for all living organisms because

a)

It provides energy for degrowth and repair of tissues

b)

It is essential for degrowth of the body

c)

It activates loss of water causing dehydration

d)

It provides energy and organic material for growth and repair of tissues

5.

Oral cavity leads into a common passage for food and air called

a)

Pharynx

b)

Larynx

c)

Nasal chamber

d)

Oesophagus

6.

Which of the following layer of gut wall is formed by mesothelium and some connective tissue

a)

Serosa

b)

Submucosa

c)

Muscularis

d)

Mucosa

7.

Brush border epithelium is present at innermost lining of

a)

Intestinal wall

b)

DCT

c)

Stomach

d)

Trachea

8.

The bile duct and pancreatic duct open together into the duodenum as the

a)

Common hepatic duct

b)

Cystic duct

c)

Common hepato-Pancreatic duct

d)

Common bile duct

9.

Which of the following statement is incorrect?

a)

30 per cent of starch is hydrolysed at pH 6.8

b)

Pepsinogen is converted into pepsin by HCl

c)

Mucus and bicarbonates present in gastric juice protect mucosal epithelium from excoriation by HCl.

d)

Intrinsic factor secreted by peptic cells help in absorption of Vit B12.

10.

All of the following enzymes are present in pancreatic juice except

a)

Amylase

b)

Carboxypeptidase

c)

Nucleotidases

d)

Lipases

11.

Ileo-cecal valve prevents the backflow of faecal matter from

a)

Duodenum to stomach

b)

Large intestine to small intestine

c)

Colon to rectum

d)

Ileum to colon

12.

Gross calorific value of carbohydrates is slightly

a)

Equal to gross calorific value of proteins

b)

More than its physiological value

c)

More than proteins

d)

Less than its physiological value

13.

The condition in which faeces are retained within the colon as the bowel movements occur irregularly, is called

a)

Vomiting

b)

Constipation

c)

Indigestion

d)

Diarrhoea

14.

Read the following statements carefully w.r.t. PEM. Choose the option with all correct statements

(a) Causes wasting of muscles in infants and children

(b) Causes failure of growth and brain development

(c) Some fat is left under the skin in marasmus

(d) Kwashiorkor is found in a child less than one year of age

a)

a & b

b)

b & c

c)

c & d

d)

a & d

15.

Which of the following products of digestion are absorbed by intestinal mucosa by simple diffusion, facilitated transport as well as by active transport?

a)

Fructose and fatty acids

b)

Chylomicron and Na+

c)

Glucose and glycerol

d)

Glucose and amino acids

16.

Enzyme pepsin works in the pH range 1.5 to What would happen to the rate of the reaction controlled by this enzyme, if there is a rise “ from 2.5 to 8?

a)

There will be no effect on rate

b)

The rate first increases then decrease

c)

The rate doubles

d)

The rate starts to decrease

17.

An enzyme obtained from a X source has been classified by enzyme commission and its unique four digit number 1.2.1.4. To which of the following class does it belong?

a)

Hydrolases

b)

Ligases

c)

Isomerases

d)

Oxidoreductases

18.

In competitive inhibition, Km value

a)

Decreases

b)

Increases

c)

Remains unchanged

d)

First increases then decreases

19.

Which of the following secondary metabolites belong to toxin category?

a)

Codeine

b)

Anthocyanin

c)

ConcanavaIin-A

d)

Abrin

20.

Statement-A : A non-competitive inhibitor binds the enzyme at a site distinct from that to which substrate binds.

Statement-B : The competitive inhibitor does not affect the rate of breakdown of the enzyme- substrate complex.

Choose the correct answer.

a)

Both correct

b)

Both incorrect

c)

only A is correct

d)

only B is correct

21.

Select the correct set of structure of protein which gives 3-dimensional view.

a)

Quaternary, primary

b)

Tertiary, quaternary

c)

Secondary, tertiary

d)

Primary, secondary

22.

Inhibition of hexokinase by glucose-6-phosphate is an example of

a)

Non-competitive and irreversible process

b)

Allosteric modulation

c)

Competitive and reversible process

d)

Competitive and irreversible process

23.

Which of the following statement is incorrect

w.r.t. enzyme

a)

Enzymes lower the activation energy which is required to start a reaction

b)

Enzymes substrate complex formation is an obligatory & transient phenomenon

c)

Enzymes are highly efficient at any temperature

d)

Active site of an enzyme is a crevice or pocket into which the substrate fits

24.

Which of the following co-factor forms coordination bonds with active site of enzyme as well as with substrate?

a)

Prosthetic group

b)

Riboflavin

c)

Metal ions

d)

Co-enzyme

25.

Read the following statements and choose the

correct option.

(A) Irreversible inhibition of enzyme activity occurs when an inhibited enzyme does not regain activity upon dilution of the enzyme inhibitor complex by addition of substrate.

(B) Inhibitors always compete with the substrate for binding with active site of an enzyme.

(C) Dilution of the enzyme — inhibitor complex by adding more amount of substrate helps in attaining the Vmax in competitive inhibition.

a)

A and B are correct, C is incorrect

b)

B and C are correct, A is incorrect

c)

A and C are correct, B is incorrect

d)

A, B and C are incorrect

26.

Metabolic pathways can lead to a more complex structure from a simple structure, for example

a)

Hydrolysis of nucleic acid into nucleotides

b)

Breakdown of protein into amino acid

c)

Acetic acid becomes cholesterol

d)

Conversion of glucose into lactic acid

27.

Select the type of enzyme involved in following reaction in which ‘Q’ represents group other than hydrogen

P — Q + R —> P + R — Q

a)

Sucrase

b)

Transferase

c)

Ligases

d)

Isomerase

28.

Identify X & Y in the given graph

a)

X-axis- Temperature Y-axis- Substrate concentration

b)

X-axis- Temperature Y-axis- pH

c)

X-axis- pH Y-axis- Enzymatic action

d)

X-axis- pH Y-axis- Substrate concentration

29.

DNA polymerase is a

a)

Protein

b)

Lipid

c)

RNA

d)

DNA

30.

Consider the following statements.

(A) Coenzyme or metal ion that is tightly bound to enzyme protein is called prosthetic group.

(B) A complete catalytic active enzyme with its bound prosthetic group is called apoenzyme.

Select the correct option.

a)

(A) is false but (B) is true

b)

Both (A) and (B) are true

c)

(A) is true but (B) is false

d)

Both (A) and (B) are false

31.

Identify the correct statement with reference to human digestive system

a)

Ileum opens into small intestine

b)

Serosa is the innermost layer of the alimentary canal

c)

IIeum is a highly coiled part

d)

Vermiform appendix arises from duodenum

32.

Match the following structures with their respective location in organs.

(A) Crypts of Lieberkuhn (i) Pancreas

(B) Glisson’s Capsule (ii) Duodenum

(C) Islets of Langerhans (iii) Small intestine

(D) Brunner’s Glands (iv) Liver

Select the correct option from the following

a)

(A) (iii) (B) (ii) (C) (i) (D) (iv)

b)

(A) (iii) (B) (i) (C) (ii) (D) (iv)

c)

(A) (ii) (B) (iv) (C) (i) (D) (iii)

d)

(A) (iii) (B) (iv) (C) (i) (D) (ii)

33.

Which of the following terms describes human dentition?

a)

Thecodont, Diphyodont, Homodont

b)

Thecodont, Diphyodont, Heterodont

c)

Pleurodont, Monophyodont, Homodont

d)

Pleurodont, Diphyodont, Heterodont

34.

The enzyme enterokinase helps in conversion of

a)

protein into polypeptides

b)

trypsinogen into trypsin

c)

caseinogen into casein

d)

pepsinogen into pepsin

35.

Identify the cells whose secretion protects the lining of gastro-intestinal tract from various enzymes.

a)

Duodenal cells

b)

Chief cells

c)

Goblet cells

d)

Oxyntic cells

36.

Match the items given in column I with those in column II and choose the correct option.

Column I Column II

A. Rennin (i) Vitamin B12

B. Enterokinase (ii) Facilitated transport

C. Oxyntic cells (iii) Milk proteins

D. Fructose (iv) Trypsinogen

a)

A-iii, B-iv, C-ii, D-i

b)

A-iv, B-iii, C-i, D-ii

c)

A-iv, B-iii, C-ii, D-i

d)

A-iii, B-iv, C-i, D-ii

37.

Anxiety and eating spicy food together in an otherwise normal human, may lead to

a)

indigestion

b)

jaundice

c)

diarrhoea

d)

vomitting

38.

Identify below given diagram & select labelled structure which is structural constituent of lymphatic system

a)

X

b)

Y

c)

Z

d)

P

39.

Identify the given diagram & identify labelled part which contains rugae in stomach & villi in intetsine

a)

P

b)

Q

c)

R

d)

S

40.

Dental formula for diphyodont teeth of human

a)

0021/0021

b)

2103/2103

c)

2102/2102

d)

2123/2123

41.

The amount of heat liberated from complete combustion of 1 g fat in a bomb calorimeter is

a)

4.1 kcal/g called physiologic values

b)

5.65 kcal/g called gross calorific value

c)

4 kcal/g called physiologic values

d)

9.45 kcal/g called gross calorific value

42.

Read the following statements

a. Kwashiorkar is produced only by protein deficiency in children more than one year in age

b. Malnutrition is a term which covers problems of undernutrition

c. Inflammation of liver is called cholecyctitis

Select correct statements

a)

a & b

b)

b & c

c)

a & c

d)

All

43.

Procarboxypeptidase is converted into carboxypeptidase by the action of enzyme which is present in

a)

Intestinal lumen

b)

Succus entericus

c)

Saliva

d)

Gastric juice

44.

A) hormonal control of the secretion of digestive juices is carried out by hormones produced by the gastric & intestinal mucosa

B) these hormones include secretin & GIP, secreted from gastric & intestinal mucosa respectively

Identify the correct statements

a)

both are correct

b)

both are incorrect

c)

Only A is correct

d)

Only B is correct

45.

Match the column

a) Brunner's gland i) Present in mucosa of small intestine

b) Wharton's duct ii) Duct of salivary gland

c) Kupffer cell iii) Macrophages of liver

d) Crypts of Leiberkuhn iv) Exclusively present in wall of duodenum

a)

a)- iv b)- iii c)- ii d)- i

b)

a)- iv b)- ii c)- iii d)- i

c)

a)- i b)- iii c)- ii d)- iv

d)

a)- iv b)- iii c)- i d)- ii