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RECALLS_PATHO-Lec_001

Total questions: 20

Worksheet time: 8mins

Name
Class
Date
1.
Nucleosomes consist of DNA segments 147 base pairs long that are wrapped around a central core structure of highly conserved low molecular weight proteins called __.
a)
Phosphate
b)
Ribose
c)
Histones
d)
Telomeres
2.
Plasma membranes are physically assembled in the ___.
a)
Golgi Apparatus
b)
Rough Endoplasmic Reticulum
c)
Lysosomes
d)
Peroxisomes
3.
This organelle is abundant in certain cell types such as gonads and liver where it is used for steroid hormone and lipoprotein synthesis, as well as for the modification of hydrophobic compounds (e.g., drugs) into watersoluble molecules for export.
a)
Rough endoplasmic reticulum
b)
Smooth endoplasmic reticulum
c)
Mitochondria
d)
Nucleus
4.
Uptake of fluids or macromolecules by the cell.
a)
Exocytosis
b)
Transcytosis
c)
Endocytosis
d)
By Carrier proteins
5.
Plays a role in the retrograde movement of microtubules.
a)
Kinesins
b)
Dyneins
6.
Plays a role in the adhesion of epithelial cells to the extracellular matrix.
a)
Occluding junctions
b)
Belt desmosomes
c)
Hemidesmosome
d)
Gap junctions
7.
In belt desmosomes, the transmembrane adhesion molecules are called ___.
a)
E-cadherins
b)
Intergrins
c)
Spot desmosome
d)
Tight junction
8.
Extracellular cell-cell signaling pathway in which cells in just the<br />immediate vicinity are affected.
a)
Autocrine signaling
b)
Paracrine signaling
c)
Synaptic signaling
d)
Endocrine signaling
9.
Checkpoint that monitors the integrity of DNA before irreversibly<br />committing cellular resources to DNA replication.
a)
G2-M checkpoint
b)
G1-S checkpoint
10.
If the genetic derangement is too severe to be repaired, the cells will undergo ___.
a)
Necrosis
b)
Apoptosis
c)
Senescence
d)
G0 state
11.
What cyclin –CDK complex regulates G2-M transition?
a)
Cyclin D-CDK4
b)
Cyclin B-CDK1
c)
Cyclin A-CDK2
d)
Cyclin E-CDK2
12.
The most abundant glycoprotein in basement membrane.
a)
Laminin
b)
Integrin
c)
Fibronectin
13.
This gives the ability of tissues to recoil and recover their shape after physical deformation is conferred by ___.
a)
Collagen
b)
Laminin
c)
Elastin
d)
Fibronectin
14.
Also called adult stem cells; they are in niches, are quiescent until there is a need for expansion and differentiation of the precursor pool.
a)
Embryonic stem cells
b)
Tissue stem cells
c)
Mesenchymal stem cells
15.
The sequence of events that results in division is called the cell cycle.
a)
S, M, G1, G2
b)
G1, G2, S, M
c)
S, G1, M, G2
d)
G1, S, G2, M
16.
Basement membrane
a)
Type I collagen
b)
Type II collagen
c)
Type III collagen
d)
Type IV collagen
17.
These are multipotent cells that can differentiate into a variety of stromal<br />cells including chondrocytes (cartilage), osteocytes (bone), adipocytes (fat), and myocytes (muscle).
a)
Embryonic stem cells
b)
Tissue stem cells
c)
Mesenchymal stem cells
18.
Consists of long polysaccharides called glycosaminoglycans that form<br />highly hydrated compressible gels that confer resistance to compressive<br />forces; in joint cartilage; provide a layer of lubrication between adjacent boney surfaces.
a)
Proteoglycans
b)
Fibronectin
c)
Collagen
d)
Elastin
19.
Most of the ATP that powers cells is made through oxidative<br />phosphorylation in the __.
a)
Nucleus
b)
Mitrochondria
c)
Golgi apparatus
d)
Peroxisomes
20.
A fluid-phase process during which the plasma membrane invaginates and is pinched off to form a cytoplasmic vesicle.
a)
Potocytosis
b)
Pinocytosis
c)
Exocytosis
d)
Carrier proteins