WorksheetsLecture 1- Foundations of Biochem.
Total questions: 38
Worksheet time: 21mins
Genome is
collection of all of a cell's DNA
collection of all functioning proteins in a cell
collection of all carbohydrates in a cell
collection of all lipids in a cell
collection of all microorganisms inhabiting a human body
Pharmacogenomic is
study of how genes affect a person's response to drugs
part of personalized medicine
the right dose of the right drug to the right patient
characterization of all aspects of the genome
Lipidome is
collection of all of a cell's DNA
collection of all functioning proteins in a cell
collection of all carbohydrates in a cell
collection of all lipids in a cell
collection of all microorganisms inhabiting a human body
Molecules may have atoms linked in the same binding order but have different 3-D spatial relationships
Configurational
Stereochemistry
Isomer
biomolecules
Proteome is
collection of all of a cell's DNA
collection of all functioning proteins in a cell
collection of all carbohydrates in a cell
collection of all lipids in a cell
collection of all microorganisms inhabiting a human body
Microbiome is
collection of all of a cell's DNA
collection of all functioning proteins in a cell
collection of all carbohydrates in a cell
collection of all lipids in a cell
collection of all microorganisms inhabiting a human body
Configurational isomers
cannot be interconverted without breaking bonds
can be interconverted without breaking bonds
Glycome is
collection of all of a cell's DNA
collection of all functioning proteins in a cell
collection of all carbohydrates in a cell
collection of all lipids in a cell
collection of all microorganisms inhabiting a human body
Conformational isomers
cannot be interconverted without breaking bonds
can be interconverted without breaking bonds
Cis isomer or trans isomer?
cis isomer
trans isomer
cis isomer or trans?
trans
cis
What characteristics define a cis isomer?
r-group on opposite sides of double bonds
r-group on the opposite side
r-group on same sides of double bonds
r-group on the same side
What characteristics define a trans isomer?
r-group on opposite sides of double bonds
r-group on the opposite side
r-group on same sides of double bonds
r-group on the same side
True or false: Chiral molecules can be superimposed on their mirror image?
true
false
True or False: Achiral molecules cannot be superimposed on their mirror image
true
false
Which of the following describes enantiomers?
same side-mirror images
non-mirror images
opposite side mirror images
mirror images
Which of the following describes diastereomers?
same side-mirror images
non-mirror images
opposite side mirror images
mirror images
Enantiomers or diastereomers?
enantiomers
diastereomers
Enantiomers or diastereomers?
enantiomers
diastereomers
Enantiomers or diastereomers?
enantiomers
diastereomers
What is stereospecificity?
most chiral molecules exist in only 5 configuration
most chiral molecules exist in only 2 configuration
most chiral molecules exist in only 1 configuration
B and C
All of the above
Which of the following is an equimolar solution of two enantiomers?
racemic mixture
racemic drugs
conformational isomers
Thalidomide is what type of drug?
racemic mixture
racemic drug
racemate
distereomer
Which of the following are methods for determining 3-D structures?
X-ray crystallography
Electron Microscope
Nuclear Magnetic Resonance
Photocrystallography
The following are all physical foundations EXCEPT
equilibrium
photosynthesis
dynamic steady state
metabolism
thermodynamics
Which of the following characteristics are associated with equilibrium?
chemical reactions tend to go to completion
completion is a specific set on concentrations
chemical reactions to not to go to completion
completion is a general set on concentrations
Enthalpy is ___ and is associated by ___
randomness; S, delta S
energy in chemical bonds; H, delta H
Gibbs; G, delta G
Entropy is ___ and is associated by ___
randomness; S, delta S
energy in chemical bonds; H, delta H
Gibbs; G, delta G
Free energy is ___ and is associated by ___
randomness; S, delta S
energy in chemical bonds; H, delta H
Gibbs; G, delta G
Exothermic is determined when
delta H >0
delta H <0
delta S <0
delta S >0
Endothermic is determined when
delta H >0
delta H <0
delta S <0
delta S >0
In entropy, the system becomes more random and less ordered when
delta H >0
delta H <0
delta S <0
delta S >0
In entropy, the system becomes more ordered and less random when
delta H >0
delta H <0
delta S <0
delta S >0
What are the factors that contribute to making delta G more negative?
positive delta S
negative delta H
positive delta H
negative delta s
What factors contribute to making delta G more positive?
positive delta S
negative delta H
positive delta H
negative delta s
All of the following are thermodynamics of biosystems EXCEPT
left alone, they would fall apart
energy input is required in order to maintain order and to grow
left alone, they would build together
exergonic reactions are coupled to endergonic reactions
Exothermic enthalpy is when
heat energy is transformed
heat is generated/released
heat is lowered
heat is non-generated
Endothermic enthalpy is when
heat energy is transformed
heat is generated/released
heat is lowered
heat is non-generated
