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WorksheetsMutation
Total questions: 15
Worksheet time: 10mins
Substitution of one base pair for another can result in a ____________ mutation that results in the conversion of an amino acid specifying codon to a termination codon.
nonsense
frameshift
chromosomal
missense
Translocation occurs when:
part of a chromosome breaks off and attaches to a non-homologous chromosome
part of a chromosome breaks off and attaches to a homologous chromosome.
crossing-over events occu
genes move from one area on a chromosome to another area on the same chromosome.
Which of the following statements is FALSE regarding non-disjunction?
Non-disjunction only happens during anaphase I meiosis
Abnormalities in the number of sex chromosomes can happen
Turner syndrome is a result of non-disjunction.
It may produce a polyploidy
1. During oogenesis, non-disjunction of sex chromosomes occurred. The ovum produced was then fertilized by a normal Y chromosome bearing sperm. Which of the following sex chromosomes is a complement of the resulting zygote?
XO
XY
XXY
XXXY
Mutation that will cause the most serious damage is
Deletion
Inversion
Duplication
Translocation
The diagram above shows the structure of chromosome which has undergone mutation. What type of mutation is shown below?
Euploidy
Insertion
Translocation
Base substitution
Choose the FALSE statement of gene mutation
It can cause Down syndrome in humans
It can occur in both somatic and germ cells
It can be caused by exposure to ionizing radiation
It can change a dominant allele into a recessive one
The table above shows types of mutation and their examples
Which of the following is correct about the types of mutations and their examples?
I II III IV
(a) (c) (b) (d)
(d) (a) (c) (b)
(b) (c) (a) (d)
(c) (d) (a) (b)
A mutagen converts adenine into a compound that pairs with cytosine. If DNA is treated with this mutagen, what type of gene mutation would occur?
Base deletion
Base substitution
Base inversion
Base insertion
Which of the following statements about sickle cell anaemia arte true?
It is caused by a single base substitution
It is caused by a base insertion on the sixth triplet code for β polypeptide of haemoglobin
Nucleotide with thymine base is substituted by nucleotide with guanine base
Glycine amino acid is substituted by valine
Which of the following types of gene mutation causes frame shift mutation
I) Single base substitution
II) Two base inversion
III) Single base insertion
IV) Single base deleteion
I and II
I and III
II and III
III and IV
chromosomal mutations cause a segment of the chromosome to repeat itself during replication.
inversion
duplication
translocation
deletion
