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WorksheetsGenetics and Evolutionary Biology Quiz Buster
Total questions: 36
Worksheet time: 1hrs 12mins
Which of the following events occurs in Anaphase of Mitosis?
Nuclear envelopes form around chromosomes
Chromatin condenses into chromosomes
Chromosomes align
Sister chromatids seperate
Homologous chromosomes move towards opposite poles
A medical technician analysing a blood sample in a clinical lab determines that the blood has both A and B antigens present on the surface. Therefore, the antigens are exhibiting a genetic characteristic known as:
Simple dominance
Incomplete dominance
Partial dominance
Semi-dominance
Co-dominance
In eukaryotes, _______ occurs for growth and repair while ______ occurs for sexual reproduction.
Mitosis and Meiosis; Meiosis
Mitosis; Meiosis
Meiosis; Mitosis
Binary fission; Meiosis
Mitosis; Binary fission
Binary fission is:
The combination of 2 cells to create 1 giant cell
Cell division by meiosis
Cell division in prokaryotes, creating 2 genetically identical daughter cells
Cell division in eukaryotes, creating 2 genetically identical daughter cells
In a diploid cell with 4 chromosome pairs (2n=8), how many sister chromatids will be found in the nucelus at prophase of mitosis?
4
6
8
16
32
What is the mode of inheritance of the following pedigree?
Autosomal recessive
Autosomal dominant
X linked dominant
X linked recessive
Centromeres are:
Positively charged proteins
Isolated chromatin from interphase cells
Constricted region of a chromosome that connects sister chromatids
Part of the chromosome that protects the end from DNase
What is the structural component of nucleic acids?
Phosphate
Sugar
Base
All of the structures listed are present in nucleic acids
The enzyme DNA polymerase requires:
Template RNA strand
rNTPs
Mn2+
Primer DNA with free 3'OH
The three phases of transcription are:
Initiation, synthesis, deletion
Initiation, elongation, deletion
Initiation, elongation, termination
Initiation, synthesis, termination
Which of the following is NOT part of the process of replication?
Helicase
Crossing over
Okazaki fragments
Topoisomerase
Exonuclease activity
What typically determines the sex of a human?
The presence of the X chromosome
The presence of the Y chromosome
X inactivation
Crossing over during meiosis
Which of the following is FALSE about endonucleases?
Bacteria's DNA is protected from them by methylation
Only cut DNA at specific nucleotide sequences
Cleave the phosphodiester bonds between nucleic acids
Produced by bacteria as a defence mechanism against bacteriophages
Which of the following is not an essential feature of cloning vectors?
Recessive selectable marker
Origin of replication
Unique restriction endonuclease cleave site
Ability to fit desired DNA fragment
Out of the following, which would be the most appropriate to clone a 400kb DNA fragment?
Bacteriophage
Cosmid
YAC
BAC
In gel electrophoresis, DNA is seperated based on:
Negative charge
Charge and size
Size
Positive charge
Which is false about cDNA libraries?
Created by reverse transcription
Composed of all the genes expressed in the tissue
Contains mRNA copies
Construction involves mRNA isolation
Consider the DNA molecule below. Which of the following DNA molecules is most likely to bind to the sticky end of this molecule?
What is the sequence of the DNA complementary strand based on the following Sanger sequencing data?
3’ – ATGCCAGTA – 5’
5’ – TACGGTCAT – 3’
3’ – TACGGTCAT – 5’
5’ – ATGCCAGTA – 3’
Which of the following is true of both Sanger Sequencing and Automated Sequencing?
The four reactions are added to different beakers
Each ddNTP has a tag attached
Each reaction is loaded into separate lanes for electrophoresis
DNA immobilization is an important step
Which of the following is the correct definition for restriction fragment length polymorphism (RFLP)?
Specific set of SNPs and other genetic variants observed on a single chromosome or part of a chromosome
Certain DNA motifs repeated (the same motif but at different rates) distributed throughout the genome
A site in the genome where a person differs by a single base pair is called a single nucleotide polymorphism
When the same restriction enzymes make different sized fragments in people due to genome differences.
Compare known sequences in the database with newly sequenced genomic DNA using BLAST tool. What does BLAST stand for?
Basic Local Assimilated Search Tool
Basic Local Alignment Search Tool
Brilliant Local Assimilated Search Tool
Brilliant Local Alignment Search Tool
Which of the following was NOT an aspect of what Lamarck believed about evolutionary biology?
Species change through time
Evolutionary change is imperceptible
Evolution occurs through adaptation to the environment
Species are related to each other by common descent
Discrete genes are the method through which traits are inherited
The upper forelimbs of humans and bats have similar skeletal structures, whereas the corresponding bones in whales have very different shapes and proportions. Genetic data suggest that all three diverged from a common ancestor. Which is the most likely explanation for this difference?
Whales are not mammals, bats and humans are
Humans and bats developed structures through natural selection, whales did not
Natural selection in an aquatic environment resulted in these significant changes
Whales mutate faster than other species, that is why they are so different
Forelimb evolution was adaptive in humans and bats, but not in whales
Which of the following is NOT a weakness of Darwinism?
No specific theory for the evolution of complexity
Saw heredity as a blending phenomenon
Was not able to identify a mechanism of inheritance
Believed in special creation and that strata represented catastrophic events which were responsible for the complete removal of species
Which of the following conditions would cause a population to fall out of Hardy-Weinberg equilibrium?
Natural selection
Extremely large population size
No gene flow
Random mating
No mutation
Robins typically lay four eggs. If more than four eggs are produced then the baby chick are malnourished, while smaller egg counts result in no viable baby chicks, this is an example of...
Disruptive selection
Directional selection
Stabilising selection
Artificial selection
Which of the following is not an effect of small populations?
Inbreeding depression
Loss of genetic diversity
Genetic drift
Gene flow
Which of the following correctly labels Taxa 1, 2 and 3?
1-Monophyletic; 2-Paraphyletic; 3-Polyphyletic
1-Monophyletic; 2-Polyphyletic; 3-Paraphyletic
1-Polyphyletic; 2-Paraphyletic; 3-Monophyletic
1-Polyphyletic; 2-Monophyletic; 3-Paraphyletic
Name and explain Mendel's 3 principles of inheritance.
What is dosage compensation of X-linked genes?
Explain which phase of meiosis non-disjunction is worse to occur and why?
Describe the steps of PCR.
List two differences between genomic libraries and cDNA libraries.
Explain the difference between gene flow and genetic drift, include how each occurs.
Explain the three levels of DNA packaging and size of the DNA at each stage.
