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DR. JONES Bone and Joint Physiology and Dr. MADRAS

Total questions: 63

Worksheet time: 33mins

Name
Class
Date
1.

A femur includes both compact and spongy bone tissues

a)

True

b)

False

2.

Trabeculae are structural characteristics of compact bone

a)

True

b)

False

3.

Most bones develop from hyaline cartilage

a)

True

b)

False

4.

The growth zone of the long bones of adolescents is the articular cartilage

a)

True

b)

False

5.

Osteoclasts develop from osteoblasts

a)

True

b)

False

6.

Osteocytes develop from osteoblasts

a)

True

b)

False

7.

The protein of the bone matrix is called hydroxyapatite

a)

True

b)

False

8.

Blood vessels travel through the central canals of compact bone

a)

True

b)

False

9.

Vitamin D promotes bone deposition, not resorption

a)

True

b)

False

10.

Parathyroid hormone promotes bone resorption and raises blood calcium concentration.

a)

True

b)

False

11.

Synovial joints are also known as synarthroses.

a)

True

b)

False

12.

The femur is held tightly in the acetabulum mainly by the round ligament.

a)

True

b)

False

13.

Synovial fluid is secreted by the bursae

a)

True

b)

False

c)

1. synovial fluid is secreted by the synovial membrane of the joint capsule and fills the bursae (EXPLANATION)

14.

Unlike most ligaments, the periodontal ligaments do not attach one bone to another.

a)

True

b)

False

15.

Calcium is required for all of the following except __________.

a)

nerve conduction

b)

blood clotting

c)

muscle contraction

d)

All of these require calcium

16.

Which of the following mineral gives bone it's rigid structure?

a)

Calcium

b)

Phosphate

c)

Collagen

d)

Hydroxyapatite

17.

Bones are made up of which of the following three tissue types?

a)

Spongy bone, and trabecular bone

b)

Spongy bone, fat, and bone marrow

c)

Compact bone, spongy, and bone marrow

d)

Compact bone, white marrow, and red marrow

18.

Which of the following is the term for the functional unit of compact bone?

a)

Haversian canal

b)

Trabeculae

c)

Osteon

d)

Lamellae

19.

Which of the following cells is responsible for depositing hydroxyapatite into bone matrix?

a)

Osteocytes

b)

Myelocytes

c)

Osteoclasts

d)

Osteoblasts

e)

Melanocytes

20.

In regards to bone marrow, "red marrow" is primarily made up of ___________ cells, while "yellow marrow" is primarily made up of ___________ cells. (hint: google hematopoietic)

a)

active. . . dormant

b)

erythrocytic. . . leukocytic

c)

hematopoietic. . . fat

d)

proliferating. . . calcified

21.

The length of long bones is increased via the hypertrophy and eventual apoptosis of chondrocytes which leave cavities that are then colonized by osteoprogenitor cells. This process is referred to as __________.

a)

osteoblast mineralization

b)

endochondral mineralization

c)

apoptotic ossification

d)

endochondral ossification

22.

Muscle is attached to the periosteum of bone via which of the following?

a)

Articular cartilage

b)

Ligaments

c)

Tendons

d)

Sutures

23.

Which of the following tissues is not part of a bone as an organ?

a)

dense connective

b)

cartilage

c)

muscle

d)

blood

24.

The organic matter of living bone includes

a)

calcium phosphate.

b)

collagen fibers and cells.

c)

calcium carbonate.

d)

magnesium and fluoride.

25.

The _______ is an example of a sesamoid bone.

a)

vertebra

b)

femur

c)

carpal

d)

patella

26.

The epiphyseal plate represents the

a)

ends of the epiphyses.

b)

shaft between the epiphyses.

c)

growth zone of hyaline cartilage.

d)

membrane around a bone.

27.

The central canal of a bone osteon contains

a)

blood vessels and nerves.

b)

osteocytes

c)

red bone marrow.

d)

yellow bone marrow.

28.

Internal and external rotation of the humerus are made possible by which joint?

a)

pivot

b)

condylar

c)

ball-and-socket

d)

saddle

e)

hinge

29.

Which of the following is the least movable?

a)

a diarthrosis

b)

a synostosis

c)

a symphysis

d)

a synovial joint

e)

a condylar joint

30.

Which of the following joints has anterior and posterior cruciate ligaments?

a)

the shoulder

b)

the elbow

c)

the hip

d)

the knee

e)

the ankle

31.

Which cells have a ruffled border and secrete hydrochloric acid?

a)

C cells

b)

osteocytes

c)

osteogenic cells

d)

osteoblasts

e)

osteoclasts

32.

The marrow cavity of an adult bone may contain

a)

myeloid tissue.(blood tissue)

b)

hyaline cartilage

c)

periosteum

d)

osteocytes

e)

articular cartilages

33.

The spurt of growth in puberty results from cell proliferation and hypertrophy in

a)

the epiphysis

b)

the epiphyseal line.

c)

compact bone.

d)

The epiphyseal plate.

e)

spongy bone.

34.

Osteoclasts are most closely related, by common descent, to

a)

osteoprogenitor cells

b)

osteogenic cells

c)

blood cells

d)

macrophage

e)

osteoblasts

35.

Which of these is not an effect of PTH?

a)

rise in blood phosphate level (PTH increases bone resorption which would increases Phosphate, but PTH also increases urine excretion of phosphate which tends to minimize the overall increase)

b)

reduction of calcium excretion

c)

increased intestinal calcium absorption (this is an indirect effect though the increase levels of Vitamin D)

d)

increased number of osteoclasts

e)

increased calcitriol synthesis

36.

Which of these are effects of PTH?

a)

rise in blood phosphate level (PTH increases bone resorption which would increases Phosphate, but PTH also increases urine excretion of phosphate which tends to minimize the overall increase)

b)

reduction of calcium excretion

c)

increased intestinal calcium absorption (this is an indirect effect though the increase levels of Vitamin D)

d)

increased number of osteoclasts

e)

increased calcitriol synthesis

37.

One long bone meets another at its

a)

diaphysis

b)

epiphyseal plate

c)

periosteum

d)

metaphysis

e)

epiphysis

38.

Calcitriol is made from

a)

calcitonin

b)

7-dehydrocholesterol

c)

hydroxyapatite.

d)

estrogen

e)

PTH

39.

What is the function of calcitonin?

a)

Increases calcium levels

b)

Inhibition of osteoblast

c)

Decreases calcium levels Changed the d to s on decrease, so it reads better

d)

Inhibits osteoclasts

40.

Which of the following can result from hyperparathyroidism?

a)

Increased bone deposition

b)

Fractures

c)

Convulsions

d)

All of the above

41.

The lubricant of a diarthrosis is called ___________________.

a)

synovial fluid

b)

hydroxyapetite

42.

A fluid-filled sac that eases the movement of a tendon over a bone is called a/an __________.

a)

gomphosis

b)

bursa

43.

The joint between a tooth and the mandible is called a/an __________.

a)

bursa

b)

gomphosis

44.

In a __________ suture, the articulating bones have interlocking wavy margins, somewhat like a dovetail joint in carpentry.

a)

Serrated

b)

Exacerbated

45.

In kicking a football, what type of action does the knee joint exhibit?

a)

Extension

b)

Flexion

46.

The menisci of the knee are functionally similar to the __________ of the temporomandibular joint.

a)

Articular Disc

b)

meniscus

47.

Compact bone lines the shaft and spongy bone is found of the heads and close to the marrow cavity

a)

True

b)

False

48.

Trabeculae are part of spongy bone

a)

True

b)

False

49.

Bones elongate at the epiphyseal plate, not the articular cartilage

a)

True

b)

False

50.

Osteoclast develop from macrophage

a)

True

b)

False

51.

Hydroxyapatite is the major mineral of bone; the major protein is collagen.

a)

True

b)

False

52.

Vit D directly leads to bone resorption

a)

True

b)

False

53.

Synovial joints are diarthroses and amphiarthroses, but never synarthroses.

a)

True

b)

False

54.

The hip has the acetabulum

a)

True

b)

False

55.

Synovial fluid is secreted by the synovial membrane of the joint capsule and fills the bursae

a)

True

b)

False

56.

The teeth are not considered bones

a)

True

b)

False

57.

Which medication has the potential to cause flashes?

a)

Raloxifene

b)

Ibandronate

58.

Which medication or medications should not be used in a person who has just had a clot?

a)

HRT

b)

ERT

c)

Raloxifene

d)

Conjugated Estrogens

e)

Bazedoxifene

59.

Which class of medications have the greatest increase in BMD?

a)

Bisphosphonates

b)

JAK Inhibitors

60.

Which medications decrease bone resorption (decrease bone loss) by inhibiting osteoclast activity?

a)

Calcium

b)

Vitamin D

c)

Estrogen

d)

Bisphosphonates

e)

Raloxifene

61.

Which medications decrease bone resorption (decrease bone loss) by inhibiting osteoclast activity?

a)

Calcitonin

b)

Denosumab

c)

Conjugated Estrogens and Bazedoxifene

d)

Raloxifene

e)

Estrogen

62.

Which of the following drugs increase new bone formation (Osteoblasts)?

a)

PTH

b)

Calcium

c)

Vitamin D

d)

Raloxifene

63.

Which of the following are true about the administration of Bisphosphonates?

a)

absorption and therapeutic effect will be reduced or eliminated if food, beverages, or other plain water, or medications are taken within 30 minutes (60 minutes for Ibandronate)

b)

Take in AM with full glass (8 ounces) of plain water AT LEAST ½ hour (60 mins with ibandronate) before food, beverages, or other medications

c)

Wait more than 30 minutes before eating (60 minutes for ibandronate)

d)

Do not lie down, remain upright (seated or standing) for at least 30 minutes (60 minutes for Ibandronate) after taking the med.