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Journal Club - NETT Trial

Total questions: 10

Worksheet time: 4mins

Name
Class
Date
1.

National Emphysema Treatment Trial (NETT) randomized how many patients

a)

1218

b)

1281

c)

1291

d)

1219

2.

Improvement in QOL at 24 months for LVRS Group was 9%

a)

True

b)

False

3.

Improvement in exercise capacity at 24 months

a)

19%

b)

14%

c)

17%

d)

15%

4.

Emphysema distribution (Upper Lobe Predominant) was

a)

63%

b)

37

c)

54

d)

46

5.

A post-hoc subgroup analysis demonstrated a mortality benefit for non-high-surgical risk patients with upper lobe disease and high baseline exercise tolerance.

a)

True

b)

False

6.

Non-high-surgical risk patients with non-upper lobe disease and high exercise tolerance experienced an increased mortality rate.

a)

True

b)

False

7.

Inclusion Criteria 1

a)

TLC: ≥150%

RV: ≥100%

b)

TLC: ≥100%

RV: ≥150%

c)

TLC: ≥100%

RV: ≥100%

d)

TLC: ≥150%

RV: ≥150%

8.

Inclusion criteria 2

a)

FEV1: ≤45%

Non-smoker for ≥ 4 months

b)

FEV1: ≤35%

Non-smoker for ≥ 12 months

c)

FEV1: ≤25%

Non-smoker for ≥6 months

d)

FEV1: ≤20%

Non-smoker for ≥3 months

9.

Exclusion Criteria

a)

FEV1: ≤20%

CO diffusion ≤20%

6MWT <140 meters

b)

FEV1: ≤40%

CO diffusion ≤40%

6MWT <160 meters

c)

FEV1: ≤30%

CO diffusion ≤20%

6MWT <120 meters

d)

FEV1: ≤15%

CO diffusion ≤25%

6MWT <140 meters

10.

What was Mean FU of trial patients

a)

27.4 Months

b)

29.2 Months

c)

29.4 Months

d)

29.7 Months