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WorksheetsDRUG USE IN SPECIAL POPULATION
Total questions: 10
Worksheet time: 6mins
Examples of drugs in pregnancy category C
Methotrexate
Morphine
Metoclopramide
Memantine
Choose all teratogenic drugs
Phenytoin
Methotrexate
Carbamazepine
Warfarin
Commonly used pediatric references
Frank Shann
Blue Book
Clinical Practice Guidelines
Recommended dose of Paracetamol in pediatrics
15 mg/kg
10 mg/kg
20 mg/kg
25 mg/kg
Effects of Aging on Volume of Distribution
(Vd)
Lower Vd for hydrophilic
drugs
Lower Vd for drugs that bind
to muscle
Higher Vd for lipophilic drugs
Lower percentage of
unbound or free drug (active)
Example of drug that do not have renal adjusted dose
Metformin
Atorvastatin
Lithium
Spironolactone
The liver is the major organ of elimination and kidneys are the major organ of drug metabolism.
True
False
Examples of special population
Obese or underweight
Pediatrics
Pregnant or breastfeeding women
Blind person
Based on the picture, which group of special populations fits them the best?
(a)
Describe FDA pregnancy category A
Animal studies have failed to demonstrate
a risk to the fetus and there are no
adequate and well-controlled studies in
pregnant women.
Adequate and well-controlled studies have
failed to demonstrate a risk to the fetus in
the first trimester of pregnancy
Animal studies have shown an adverse
effect n the fetus and there are no
adequate and well-controlled studies in
humans
Studies in animals and pregnant woman
have shown evidence of fetal harm
